Targeted Proteins Research: Medicine/Pharmacology

Project ID Project Theme Principal Investigator Affiliation
MPA1 Structural analysis of molecules related to the innate immune system Shizuo Akira (2007-2009)
Ken Ishii (2010-)
Immunology Frontier Research Center, Osaka University
MPA2 Drug discovery-oriented analysis for structure and function of DOCK2 signaling molecules Yoshinori Fukui Medical Institute of Bioregulation, Kyushu University
MPA3 Study on reactive oxygen-producing systems involved in neural cell death and structure-based discovery of their inhibitors Hideki Sumimoto Medical Institute of Bioregulation, Kyushu University
MPA4 Structural analysis of γ-secretase complex for the development of the treatment for Alzheimer's disease Taisuke Tomita Graduate School of Pharmaceutical Sciences, The University of Tokyo
MPA5 Development of anti-trypanosome drugs targeting nucleotides biosynthesis and red-ox regulatory pathways >>More on this project Kiyoshi Kita Graduate School of Medical Science, The University of Tokyo
MPA6 Structure-based functional analyses and development of drug intervention in metabolic syndrome and diabetes- AdipoR/AMPK/ACC as key targets Takashi Kadowaki Graduate School of Medical Science, The University of Tokyo
MPB1 Structural and Functional Analysis of a Molecular Target FROUNT for Drug Discovery Kouji Matsushima Graduate School of Medical Science, The University of Tokyo
MPB2 Development of new compounds for fibrosis therapy Junn Yanagisawa Graduate School of Life and Environmental Sciences, University of Tsukuba
MPB3 Structure and drug development of NPP family members involved in cancer and various diseases Junken Aoki Graduate Schoo of Pharmaceutical Sciences, Tohoku University
MPB4 Structural and functional analysis of semaphorins and their receptors Atsushi Kumanogoh Research Institute for Microbial Diseases, Osaka University