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[ 2012/11/5 ] - [2012/09/06] - The Biological Magnetic Resonance Bank (BMRB) is facing the threat of having its funding discontinued. Concerned about this situation, the editors of Nature Structural & Molecular Biology have asked the community why it is important to continue to support the BMRB.

[ 2012/06/11 ] -Professor Yoshinori Ohsumi was interviewed in the April 16 issue of J. Cell Biol.

[ 2012/02/23 ] -A new distributed research infrastructure for the science of structural biology called " Instruct " has been launched in Europe.

[ 2012/02/17 ] -Structural study on channelrhodopsins by Osamu Nereki and his colleagues was featured in the cover of the February 16 issue of Nature.

[ 2011/11/07 ] -New addition to the Protein 3000 Structure Gallery; Now, the number of structures in the Protein 3000 Structure Gallery is 3783 with the addition of 106 structural data produced from the Protein 3000 Project and recently registered in the PDB.

[ 2011/04/05 ] -2011 Tohoku earthquake and tsunami
The magnitude-9.0 earthquake and its associated tsunami struck northeastern Japan on 11 March.

[ 2011/02/17 ] -The 4th Symposium on Targeted Proteins Research Program will be held on March 11th, 2011 at the University of Tokyo.

[ 2010/10/15 ] -Two new bioinformatics tools are now available; TP Atlas (Targeted Proteins Research achievements database) and PCI DB (Protein-Compound Interaction database).

[ 2010/08/02 ] -Nature News report that, referring to Targeted Proteins Research Program, Phase III of Protein Structural Initiative in USA puts emphasis on troublesome and medically relevant proteins in the name of PSI:Biology.

[ 2009/12/18 ] -Science magazine selected the research advances in abscisic acid receptors, in which Professors Tanokura, Shinozaki and their colleagues of TPRP played a crucial role (see TP Press Release on Research), as a runners-up at its "Breakthrough of the Year" section.

[ 2009/12/02 ] -Both Nature (Japan budget threat sparks backlash) and Science (Sparring Intensifies Over Japan's Science Budget) reported on cuts in scientific research funding recommend by the government-appointed working panel. List of overseas reports on this subject is here.

[ 2009/11/10 ] -Dr. Ada E.Yonath of Weizmann Institute of Science, a recipient of Nobel Prize in Chemistry this year, will be the plenary lecturer and panelist at the upcoming Symposium on TPRP (scheduled on March 5th, 2010).

[ 2009/09/10 ] -The Interim Evaluation Report on TPRP was published.

[ 2009/08/17 ] -Four information retrieval and analysis systems - Amino Acids Sequences Database (CASA db), On-demand Structural Information Database (FUJI DB), Protein Experimental Information Management System (PRIEMS), Solubility Database of All E.coli Proteins (eSOL) - are now freely available.

[ 2009/07/30 ] -NIGMS (National Institute of General Medical Sciences) of NIH plans to fund five grant programs to support a new Protein Structure Initiative program called PSI: Biology, and late last week released two grant announcements - "Centers for Membrane Protein Structure Determination" and "Consortia for High-Throughput-Enabled Structural Biology Partnerships". ......More

[ 2009/05/02 ] The National Academy of Sciences announced the election of Dr.Shizuo Akira, director of Immunology Frontier Research Center, Osaka University, as one of new foreign associates.

[ 2009/02/23 ] MetLife Foundation granted its Award for Medical Research in Alzheimer's Disease to Takeshi Iwatsubo, M.D., professor in the Department of Neuropathology in the Graduate School of Medicine at the University of Tokyo.

[ 2009/02/09 ] NIGMS (National Institute of General Medical Sciences) of NIH announced plans for the next Protein Structure Initiative (PSI).
Proposals of High-Throughput Structural Biology succeeding the current PSI-II (Protein Structure Initiative, Phase II, 2005/06 - 2010/06) were published along with recommendations from PSI Advisory Committee.

NIGMS Plans Changes to Protein Structure Initiative
The newly-named Protein Structure Initiative's PSI:Biology program will spend $37 million next year to support partnerships between biologists and high-throughput protein structure centers. February 13, 2009, GenomeWeb Daily News, copyright 2009 GenomeWeb LLC

[ 2009/01/30 ] We have refreshed the TPRP website. (2009/01/30)
If you have any inquiries or suggestions regarding this website, please contact us at

[ 2009/01/27 ] Review article on the molecular mechanism of proteasome assembly by Keiji Tanaka, et al. of the Tokyo Metropolitan Institute of Medical Science was featured at the Cover on February, 2009 issue of Nature Reviews Molecular Cell Biology

[ 2009/01/16 ] The 2nd Symposium on Targeted Proteins Research Program was held on January 15th, 2009 in Tokyo.

[ 2008/11/27 ] News release from TPRP was posted below

[ 2008/09/22 ] Progress on Targeted Proteins Research Program was presented at ICSG International Conference on Structural Genomics 2008. Posters are here

[ 2008/09/08 ] The official brochure (in Japanese) for Targeted Proteins Research Program was published

[ 2008/08/29 ] Targeted Proteins Research Program was featured in Kagaku Shinbun (Weekly Science News in Japan)

[ 2008/08/19 ] News release from TPRP was posted below

[ 2008/07/22 ] News release from TPRP was posted below

[ 2008/07/10 ] The official website (English version) was launched

[ 2008/04/22 ] Brochure (in Japanese) entitled, "The path our proteins research will carve", was published. Two National Projects funded by MEXT, Protein Structural and Functional Analysis Project (Proteins 3000, 2002-2006) and Targeted Proteins Research Program (2007-2011) are featured.

[ 2008/03/31 ] New structural and functional work by Keiji Tanaka, et al. of the Tokyo Metropolitan Institute of Medical Science reveals the role of a chaperone complex in directing assembly of the proteasome core, or 20S, particle.
The work was featured at the Cover by on Nature Structural and Molecular Biology, vol.15, issue 3. See also: News and Views

[ 2008/02/14 ] The 1st Symposium on Targeted Proteins Research Program was held on February 12th, 2008 in Tokyo. The resume of the Symposium is here (in Japanese)

[ 2007/10/01 ] The official website was launched

[ 2008/06/17 ] News release from TPRP was posted below

[ 2008/06/13 ] News release from TPRP was posted below

[ 2007/09/03 ] A trial version of the official site was opened