Targeted Proteins Research: Fundamental Biology

Project ID Project Theme Principal Investigator Affiliation
FBA1 Structural and functional studies of bacterial type Ⅲ and type Ⅳ protein export systems Katsumi Imada Graduate School of Frontier Biosciences, Osaka University
FBA2 Structural basis for dynamic formation and mechanistic actions of huge and complicated proteolytic machinery >>More on this project
Keiji Tanaka The Tokyo Metropolitan Institute of Medical Science, Tokyo Metropolitan Organization for Medical Research
FBA3 Structural basis of Atg proteins essential for autophagy Fuyuhiko Inagaki Graduate School of Pharmaceutical Sciences, Hokkaido University
FBA4 Structural biology of transcription factors and histone modification factors Yoshifumi Nishimura International Graduate School of Arts and Sciences, Yokohama City University
FBA5 Structure and function of voltage-sensor domain proteins Yasushi Okamura Graduate School of Medicine, Osaka University
FBA6 Structure-function analysis of protein complexes that regulate vesicular traffic Soichi Wakatsuki Institute of Materials Structure Science, High Energy Accelerator Research Organization(KEK)
FBA7 Structural studies of the cell-cell junctional proteins Toshiaki Sakisaka Graduate School of Medicine, Kobe University
FBA8 Mechanism underlying selective activation of NF-kB via linear polyubiquitination Kazuhiro Iwai Graduate School of Frontier Biosciences, Osaka University
FBB1 Structural Basis of Sensor System for Cytoprotective Gene Expression Responding to Carcinogens and Oxidative Stress Masayuki Yamamoto Graduate School of Medicine, Tohoku University
FBB2 Solid-state NMR investigation on functional and irregular structures of H+-ATPsynthase Fo (2007-2009)
Investigation on the structure and function of ATP-generating membrane protein systems (2010-)
Hideo Akutsu Institute for Protein Research, Osaka University
FBB3 3D structural and functional analyses for elucidation of the mechanism of mitochondrial respiration (2007-2009) Shinya Yoshikawa Graduate School of Life Science, University of Hyogo
FBB4 Towards structure-based design of novel inhibitors for V -ATPase (2007-2009)
Membrane transporters: structure and function of important drug targets (2010-)
So Iwata Graduate School of Medicine, Kyoto University
FBB5 Elucidation of the mechanism of high-order cellular functions achieved by non-coding RNAs Osamu Nureki Institute of Medical Science, The University of Tokyo