JW ID ECK number b number Gene name K-12 Locus name K-12 Synonyms of locus names K-12 Minus Sol TF Sol GroE Sol KJE Sol Minus uM TF uM GroE uM KJE uM Minus ug/ml TF ug/ml GroE ug/ml KJE ug/ml calculated MW(kDa) calculated pI Type of gene product Gene product description Cell location Structure (PDB) id SCOP assignment JW0003 ECK0004 b0004 thrC thrC 46.53 45.8 83.44 63.61 0.863 0.761 0.78 0.814 40.62 35.81 36.71 38.33 47.056 5.71 e threonine synthase Cytoplasmic 53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes JW0005 ECK0006 b0006 yaaA yaaA 14.01 26.65 52.96 17.69 1.199 1.014 1.162 1.86 35.43 29.98 34.34 54.96 29.555 8.74 o conserved protein Cytoplasmic JW0019 ECK0021 b0020 nhaR nhaR yaaB -!- antO 16.16 30.1 38.47 66.19 0.771 0.614 1.209 1.195 26.42 21.04 41.41 40.91 34.246 6.24 r DNA-binding transcriptional activator Cytoplasmic JW0035 ECK0037 b0036 caiD caiD yaaL 8.66 7.89 39.76 48.51 5.407 3.977 5.397 6.402 174.51 128.34 174.2 206.62 32.275 6.94 e crotonobetainyl CoA hydratase Cytoplasmic 52096; ClpP/crotonase JW0048 ECK0050 b0049 apaH apaH cfcB 19.64 30.13 68.57 74.12 1.434 1.126 1.633 1.592 44.81 35.2 51.04 49.76 31.258 5.9 e diadenosine tetraphosphatase Cytoplasmic 56300; Metallo-dependent phosphatases JW0061 ECK0063 b0062 araA araA 1.72 3.55 52.91 19.46 3.917 2.463 3.678 4.243 219.41 138 206.06 237.7 56.021 6.42 e L-arabinose isomerase Cytoplasmic JW0062 ECK0064 b0063 araB araB 25.2 47.28 74.11 51.15 0.692 0.322 0.533 0.879 42.25 19.66 32.51 53.66 61.016 5.63 e L-ribulokinase Cytoplasmic 53067; Actin-like ATPase domain JW0063 ECK0065 b0064 araC araC 20.22 36.57 48.95 67.92 0.688 0.946 1.188 1.149 22.94 31.57 39.63 38.33 33.355 7.09 r DNA-binding transcriptional dual regulator Cytoplasmic 46689; Homeodomain-like -!- 51215; Regulatory protein AraC JW0065 ECK0067 b0066 thiQ thiQ sfuC -!- yabJ 7.05 12.6 31.02 15.06 4.335 3.708 5.902 4.962 108.27 92.61 147.43 123.94 24.979 9.79 t thiamin transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW0068 ECK0070 b0069 sgrR sgrR yabN 2.01 4.11 23.13 40.32 1.693 1.421 1.738 1.579 108.24 90.85 111.12 100.95 63.92 6.82 r DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW0073 ECK0076 b0074 leuA leuA 7.81 9.6 46.24 55.13 1.054 1.271 1.458 3.277 60.32 72.74 83.46 187.52 57.232 5.84 e 2-isopropylmalate synthase Cytoplasmic 51366; Ribulose-phoshate binding barrel JW0075 ECK0078 b0076 leuO leuO 1.12 2.1 8.63 17.93 6.069 5.364 5.895 4.025 216.42 191.29 210.19 143.54 35.658 6.29 r DNA-binding transcriptional activator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW0076 ECK0079 b0077 ilvI ilvI 3.25 13.8 31.09 84.73 1.619 1.284 1.1 1.4 101.88 80.79 69.19 88.1 62.919 6.24 e "acetolactate synthase III, large subunit" Cytoplasmic 52467; DHS-like NAD/FAD-binding domain -!- 52518; Thiamin diphosphate-binding fold (THDP-binding) JW0077 ECK0080 b0078 ilvH ilvH brnP 5.95 6.52 8.55 6.7 6.289 6.287 6.765 6.77 112.95 112.91 121.49 121.59 17.959 9.55 e "acetolactate synthase III, thiamin-dependent, small subunit" Cytoplasmic 55021; Regulatory domain in the aminoacid metabolism JW0094 ECK0097 b0096 lpxC lpxC asmB -!- envA 26.04 25.81 96.39 109.8 1.939 1.835 2.34 1.888 65.76 62.24 79.38 64.02 33.917 6.27 e UDP-3-O-acyl N-acetylglucosamine deacetylase Cytoplasmic JW0103 ECK0106 b0107 hofB hofB hopB 26.82 36.01 85.47 88.13 1.035 1.023 0.967 1.044 52.34 51.72 48.92 52.78 50.569 6.55 d conserved protein with nucleoside triphosphate hydrolase domain Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW0109 ECK0112 b0113 pdhR pdhR yacB -!- dcuA -!- aceC -!- genA 9.56 18.01 21.15 23.61 1.628 1.471 1.342 1.603 47.86 43.25 39.46 47.14 29.396 6.65 r DNA-binding transcriptional dual regulator Cytoplasmic 46785; Winged helix JW0110 ECK0113 b0114 aceE aceE 36.68 120.33 41.3 58.01 0.095 0.083 0.249 0.226 9.43 8.22 24.82 22.54 99.553 5.62 e "pyruvate dehydrogenase, decarboxylase component E1, thiamin-binding" Cytoplasmic 1RP7 52518; Thiamin diphosphate-binding fold (THDP-binding) -!- 52922; Transketolase C-terminal domain-like JW0117 ECK0120 b0121 speE speE 58.26 63.44 98.92 79.23 1.005 1.078 1.118 1.266 32.46 34.79 36.09 40.88 32.285 5.87 e spermidine synthase (putrescine aminopropyltransferase) Cytoplasmic 53335; S-adenosyl-L-methionine-dependent methyltransferases JW0123 ECK0126 b0127 yadG yadG 23.59 41.47 85.2 120.37 1.163 1.23 1.282 1.123 40.27 42.58 44.38 38.85 34.612 9.16 pt predicted transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW0125 ECK0128 b0129 yadI yadI agaX 19.31 57.47 101.07 64.62 0.802 0.669 0.857 0.819 13.25 11.05 14.17 13.54 16.524 6.74 pt predicted PTS Enzyme IIA Cytoplasmic "53062; IIA domain of mannose transporter, IIA-Man" JW0142 ECK0145 b0146 sfsA sfsA sfs1 -!- sfs 27.05 28.25 80.98 107.3 1.573 1.61 1.892 1.208 41.21 42.2 49.57 31.64 26.203 7.62 pr predicted DNA-binding transcriptional regulator Cytoplasmic JW0144 ECK0147 b0148 hrpB hrpB yadO 23.12 35.38 49.03 67.88 0.19 0.127 0.213 0.185 16.93 11.34 19 16.44 89.05 6.56 pe predicted ATP-dependent helicase Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW0156 ECK0159 b0160 dgt dgt optA 11.84 33.69 70.78 51.93 0.346 0.34 0.578 0.505 20.55 20.19 34.31 29.96 59.333 7.6 e deoxyguanosine triphosphate triphosphohydrolase Cytoplasmic JW0175 ECK0179 b0180 fabZ fabZ sefA -!- yaeA -!- sabA -!- sfhC 24.21 29.07 36.81 31.95 1.877 1.882 1.757 1.977 31.93 32.02 29.89 33.64 17.016 8.2 e (3R)-hydroxymyristol acyl carrier protein dehydratase Cytoplasmic 54637; Thioesterase/thiol ester dehydrase-isomerase JW0176 ECK0180 b0181 lpxA lpxA 33.31 44.02 88.21 102.53 2.191 1.567 2.894 1.991 61.49 43.96 81.19 55.87 28.058 7.34 e UDP-N-acetylglucosamine acetyltransferase Cytoplasmic 1LXA 51161; Trimeric LpxA-like enzymes JW0180 ECK0184 b0185 accA accA 65.02 76.2 109.13 93.16 1.179 1.047 1.772 0.985 41.52 36.86 62.37 34.66 35.201 6.65 e "acetylCoA carboxylase, carboxytransferase, alpha subunit" Cytoplasmic 52096; ClpP/crotonase JW0181 ECK0185 b0186 ldcC ldcC ldc -!- ldcH 4.44 23.22 48.52 74.08 0.34 0.205 0.315 0.398 27.4 16.51 25.36 32.02 80.495 5.58 e "lysine decarboxylase 2, constitutive" Cytoplasmic 53383; PLP-dependent transferases -!- 55904; Ornithine decarboxylase C-terminal domain JW0190 ECK0194 b0194 proS proS drp -!- drpA 20.81 55.96 42.41 77.49 0.494 0.479 0.709 0.729 31.43 30.49 45.07 46.35 63.61 5.28 e prolyl-tRNA synthetase Cytoplasmic 52954; Anticodon-binding domain of Class II aaRS -!- 55681; Class II aaRS and biotin synthetases -!- 55826; Hypothetical protein HI1434 (YbaK homologue) JW0195 ECK0199 b0199 metN metN abc -!- metD 15.23 20.44 26.57 55.57 4.74 3.654 4.976 5.033 178.95 137.95 187.83 190 37.749 6.52 t DL-methionine transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW0198 ECK0208 b0208 yafC yafC 10.69 16.47 36.54 44.08 4.605 4.413 5.388 5.497 155.39 148.89 181.8 185.47 33.741 8.02 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW0205 ECK0215 b0215 dnaQ dnaQ mutD 5.99 5.85 41.25 60.26 8.043 9.291 8.351 6.365 217.72 251.49 226.05 172.3 27.068 6.27 e DNA polymerase III epsilon subunit Cytoplasmic 53098; Ribonuclease H-like JW0221 ECK0232 b0231 dinB dinB dinB -!- dinP 13.97 8.65 44.9 47.51 2.81 2.151 3.335 2.345 110.96 84.93 131.68 92.59 39.488 9.69 e DNA polymerase IV Cytoplasmic 56672; DNA/RNA polymerases JW0223 ECK0234 b0233 yafO yafO 21.81 50.09 95.16 118.99 1.068 0.97 0.842 1.098 16.52 15 13.03 16.99 15.475 8.46 pf predicted toxin of the YafO-YafN toxin-antitoxin system Cytoplasmic JW0225 ECK0236 b0235 ykfJ ykfJ 12.89 42.13 39.58 50.95 4.371 3.082 3.619 3.989 42.9 30.25 35.52 39.15 9.814 10.61 o conserved protein Cytoplasmic JW0229 ECK0240 b0239 frsA frsA yafA 7.78 22.58 45.02 64.36 2.554 2.165 2.429 1.759 119.97 101.67 114.05 82.6 46.964 7.07 r "hydrolase, binds to enzyme IIA(Glc)" Cytoplasmic 53474; alpha/beta-Hydrolases JW0234 ECK0246 b0245 ykfI ykfI 37.66 68.26 62.2 101.97 2.177 2.191 2.509 2.893 28.07 28.25 32.36 37.31 12.896 10.04 h CP4-6 prophage; toxin of the YkfI-YafW toxin-antitoxin system Cytoplasmic JW0235 ECK0247 b0246 yafW yafW 5.13 7.31 18.37 31.01 12.506 11.645 14.164 14.798 149.19 138.93 168.97 176.54 11.93 7.28 h CP4-6 prophage; antitoxin of the YkfI-YafW toxin-antitoxin system Cytoplasmic JW0236 ECK0249 b0247 ykfG ykfG 29.03 39.35 62.82 59.31 1.709 1.615 1.892 1.751 30.91 29.21 34.22 31.68 18.09 9.91 h CP4-6 prophage; predicted DNA repair protein Cytoplasmic JW0240 ECK0253 b0251 yafY yafY 6.68 22.79 9.16 56.29 2.689 2.914 2.705 2.679 88.67 96.08 89.19 88.35 32.975 8.19 h CP4-6 prophage; predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix JW0242 ECK0254 b0252 yafZ yafZ 5.2 8.87 25.08 28.15 2.345 2.291 2.71 2.492 72.76 71.07 84.1 77.33 31.029 9.91 h CP4-6 prophage; conserved protein Cytoplasmic JW0244 ECK0256 b0254 perR perR katC 6.31 14.27 31.85 50.25 1.286 1.509 1.919 1.56 43.21 50.7 64.48 52.43 33.605 6.82 h CP4-6 prophage; predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW0247 ECK0259 b0257 insO insO-1 6.99 21.97 27.48 49.95 2.326 1.721 2.145 2.162 36.86 27.28 34 34.26 15.849 10.08 h "CP4-6 prophage; partial transposase of insertion element IS911A, interrupted by insertion of IS30 element." Cytoplasmic 53098; Ribonuclease H-like JW0258 ECK0266 b4505 ykgN ykgN 11.3 25.07 16.22 95.21 3.223 2.697 3.553 3.847 41.41 34.65 45.64 49.42 12.846 8.77 ph predicted IS protein Cytoplasmic 46689; Homeodomain-like JW0259 ECK0267 b0266 yagB yagB 7.83 12.91 53.14 66.51 4.121 3.557 4.205 4.308 54.3 46.87 55.41 56.77 13.177 8.05 h CP4-6 prophage; conserved protein Cytoplasmic JW0260 ECK0268 b0267 yagA yagA 4.13 9.8 48.21 34.97 0.641 0.655 0.976 0.652 28.04 28.64 42.68 28.52 43.745 9.79 h CP4-6 prophage; predicted DNA-binding transcriptional regulator Cytoplasmic 46689; Homeodomain-like -!- 53098; Ribonuclease H-like JW0266 ECK0274 b0273 argF argF Arg5 -!- argD 13.73 17.42 49.83 90.06 2.533 2.645 2.9 2.266 93.18 97.32 106.68 83.36 36.786 6.18 h "CP4-6 prophage; ornithine carbamoyltransferase 2, chain F" Cytoplasmic 53671; Aspartate/ornithine carbamoyltransferase JW0272 ECK0277 b0278 yagL yagL 13.58 26.16 11.97 51.29 1.312 1.546 1.367 1.11 35.76 42.14 37.27 30.26 27.264 9.87 h CP4-6 prophage; DNA-binding protein Cytoplasmic 46689; Homeodomain-like -!- 53041; Resolvase-like JW0273 ECK0278 b0279 yagM yagM 12.78 27.54 25.64 99.38 0.474 0.559 0.438 0.417 15.46 18.24 14.29 13.61 32.652 8.69 h CP4-6 prophage; predicted protein Cytoplasmic JW0276 ECK0281 b0282 yagP yagP 9.82 20.84 53.05 28.52 2.206 1.922 2.308 2.217 33.96 29.59 35.53 34.14 15.396 9.16 pr predicted transcriptional regulator Cytoplasmic 53850; Periplasmic binding protein-like II JW0277 ECK0282 b0283 yagQ yagQ 8.39 17.63 65.08 73.46 0.861 0.743 0.873 0.611 30.06 25.95 30.49 21.35 34.921 7.02 o conserved protein Cytoplasmic JW0298 ECK0304 b0305 ykgD ykgD 7.71 6.72 42.15 23.94 5.593 5.395 6.779 5.133 175.89 169.65 213.17 161.42 31.447 7.55 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46689; Homeodomain-like -!- 51182; RmlC-like JW0303 ECK0309 b0311 betA betA 6.99 20.78 61.62 75.02 0.974 1.097 1.226 1.156 60.18 67.81 75.78 71.44 61.807 5.78 e "choline dehydrogenase, a flavoprotein" Cytoplasmic "51905; FAD/NAD(P)-binding domain -!- 54373; FAD-linked reductases, C-terminal domain" JW0305 ECK0311 b0313 betI betI 17.63 32.1 65.71 95.59 3.693 3.504 3.735 3.354 80.52 76.4 81.43 73.12 21.802 10.86 r DNA-binding transcriptional repressor Cytoplasmic 46689; Homeodomain-like JW0307 ECK0313 b0315 yahA yahA 23.94 39.96 45.8 67.16 1.179 1.186 1.62 1.325 47.97 48.26 65.92 53.93 40.684 6.42 pr predicted DNA-binding transcriptional regulator Cytoplasmic "46894; C-terminal, effector domain of the bipartite response regulators" JW0311 ECK0317 b0319 yahE yahE 2.46 4.15 25.11 10.53 5.032 3.794 5.055 4.498 162.22 122.3 162.96 144.99 32.237 6.73 o predicted protein Cytoplasmic JW0322 ECK0328 b0330 prpR prpR yahP 18.77 30.41 28.27 64.11 0.462 0.474 0.528 0.39 27.09 27.75 30.92 22.85 58.595 8.62 r DNA-binding transcriptional regulator Cytoplasmic 48283; FIS-like -!- 52540; P-loop containing nucleotide triphosphate hydrolases JW0325 ECK0331 b0334 prpD prpD acnC -!- yahT 9.13 16.23 59.46 76.95 0.746 0.887 0.809 0.763 40.19 47.81 43.57 41.09 53.891 6.19 e 2-methylcitrate dehydratase Cytoplasmic 1SZQ JW0326 ECK0332 b0335 prpE prpE yahU 12.64 30.66 71.91 91.65 0.24 0.403 0.396 0.347 16.62 27.91 27.4 24.05 69.274 5.99 pe predicted propionyl-CoA synthetase with ATPase domain Cytoplasmic 56801; Firefly luciferase-like JW0328 ECK0334 b0337 codA codA 18.34 22.86 104.84 123.17 1.533 1.509 1.226 1.707 72.9 71.73 58.28 81.13 47.542 6.1 e cytosine deaminase Cytoplasmic 1K70 51338; Composite domain of metallo-dependent hydrolases -!- 51556; Metallo-dependent hydrolases JW0337 ECK0343 b0346 mhpR mhpR 3.82 19.64 12.9 27.19 2.385 1.365 2.451 2.638 84.78 48.51 87.11 93.79 35.549 9.09 r "DNA-binding transcriptional activator, 3HPP-binding" Cytoplasmic 46785; Winged helix JW0338 ECK0344 b0347 mhpA mhpA 4.32 10.33 48.05 78.63 0.575 0.575 0.479 0.447 35.75 35.75 29.77 27.77 62.129 8 e 3-(3-hydroxyphenyl)propionate hydroxylase Cytoplasmic 51735; NAD(P)-binding Rossmann-fold domains -!- 51905; FAD/NAD(P)-binding domain JW0339 ECK0345 b0348 mhpB mhpB 12.33 25.7 53.62 81.81 2.061 2.316 2.699 2.811 70.4 79.1 92.19 96.01 34.156 5.98 e "2,3-dihydroxyphenylpropionate 1,2-dioxygenase" Cytoplasmic 53213; LigB subunit of an aromatic-ring-opening dioxygenase LigAB JW0340 ECK0346 b0349 mhpC mhpC 17.9 33.22 86.84 58.3 2.355 1.907 1.921 2.297 76.68 62.09 62.53 74.77 32.553 7.03 e "2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase" Cytoplasmic 53474; alpha/beta-Hydrolases JW0343 ECK0349 b0352 mhpE mhpE 7.82 11.67 71.72 64.44 2.38 2.075 2.513 2.437 86.7 75.6 91.56 88.8 36.432 6.15 e "4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase, class I" Cytoplasmic 51366; Ribulose-phoshate binding barrel JW0346 ECK0352 b0355 frmB frmB yaiM 7.31 16.87 34.27 35.59 1.455 1.417 1.433 1.454 45.67 44.5 44.99 45.64 31.393 6.35 pe predicted esterase Cytoplasmic 53474; alpha/beta-Hydrolases JW0358 ECK0363 b0366 tauB tauB ssiB -!- yaiQ 18.2 23.95 51.29 24.25 1.879 1.985 2.523 1.642 53.11 56.12 71.32 46.41 28.267 7.95 t taurine transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW0361 ECK0366 b0369 hemB hemB ncf 7.08 15.62 81.82 20.03 2.272 2.048 2.733 2.858 80.83 72.87 97.23 101.68 35.58 5.85 e porphobilinogen synthase Cytoplasmic 51569; Aldolase JW0385 ECK0389 b0394 mak mak yajF 8.38 17.63 26 35.59 2.127 1.285 2.401 1.301 69.04 41.71 77.95 42.23 32.462 6.21 e manno(fructo)kinase Cytoplasmic 53067; Actin-like ATPase domain JW0387 ECK0391 b0397 sbcC sbcC rmuA 22.9 74.8 37.43 103.82 0.125 0.033 0.136 0.109 14.82 3.89 16.15 12.98 118.585 5.59 e "exonuclease, dsDNA, ATP-dependent" Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW0393 ECK0397 b0403 malZ malZ 5.65 12.96 73.62 57.68 0.325 0.276 0.365 0.248 22.49 19.08 25.25 17.12 69.103 6.25 e maltodextrin glucosidase Cytoplasmic "51011; alpha-Amylases, C-terminal beta-sheet domain -!- 51445; (Trans)glycosidases" JW0394 ECK0398 b0404 yajB yajB 3.31 3.14 8.91 5.21 7.788 7.65 8.129 8.796 178.64 175.47 186.45 201.77 22.938 6.61 o conserved protein Cytoplasmic JW0396 ECK0400 b0406 tgt tgt 13.65 40.03 96.66 94.47 0.76 0.421 0.696 0.767 32.32 17.93 29.64 32.62 42.549 6.52 e tRNA-guanine transglycosylase Cytoplasmic 51713; tRNA-guanine transglycosylase JW0409 ECK0413 b0419 yajO yajO 2.32 5.59 34.68 9.16 4.986 4.073 4.765 4.925 181.37 148.14 173.33 179.12 36.374 5.7 pe "predicted oxidoreductase, NAD(P)-binding" Cytoplasmic 51430; NAD(P)-linked oxidoreductase JW0410 ECK0414 b0420 dxs dxs yajP 21.32 51.9 81.27 78.66 0.725 0.514 0.638 0.791 48.96 34.74 43.08 53.45 67.549 6.53 e "1-deoxyxylulose-5-phosphate synthase, thiamine-requiring, FAD-requiring" Cytoplasmic 52518; Thiamin diphosphate-binding fold (THDP-binding) -!- 52922; Transketolase C-terminal domain-like JW0435 ECK0439 b0445 ybaE ybaE 9.16 20.01 41.67 56.64 0.428 0.363 0.477 0.473 27.79 23.58 30.99 30.73 64.941 7.24 pt predicted transporter subunit -!- periplasmic-binding component of ABC superfamily Cytoplasmic 53850; Periplasmic binding protein-like II JW0437 ECK0441 b0447 ybaO ybaO 23.33 30.2 44.72 41.81 2.861 3.023 3.176 2.997 49.82 52.66 55.32 52.2 17.417 7.23 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 69732; Lrp/AsnC-like transcriptional regulator C-terminal domain JW0442 ECK0446 b0452 tesB tesB 33.34 42.21 69.45 82.52 1.807 1.548 2.244 2.162 57.71 49.43 71.66 69.05 31.937 6.74 e acyl-CoA thioesterase II Cytoplasmic 1C8U 54637; Thioesterase/thiol ester dehydrase-isomerase JW0448 ECK0453 b0459 maa maa mac -!- macC -!- ylaD 18 68.51 80.97 76.16 1.312 0.864 1.404 1.637 26.34 17.35 28.19 32.86 20.076 7.26 e maltose O-acetyltransferase Cytoplasmic 51161; Trimeric LpxA-like enzymes JW0464 ECK0469 b0475 hemH hemH popA -!- visA 16.07 29.21 69.53 99.86 1.154 1.236 2.104 1.971 41.36 44.3 75.43 70.65 35.847 6.99 e ferrochelatase Cytoplasmic 53800; Chelatase JW0488 ECK0493 b0499 ylbH ylbH 27.53 82.8 92.13 106.81 1.02 0.842 0.957 0.893 27.46 22.67 25.77 24.04 26.931 6.31 h "conserved protein, rhs-like" Cytoplasmic JW0491 ECK0496 b0503 ybbB ybbB 1.4 4.53 22.11 6.17 6.628 4.004 4.791 3.914 272.22 164.43 196.75 160.76 41.069 6.39 e "tRNA 2-selenouridine synthase, selenophosphate-dependent" Cytoplasmic 52821; Rhodanese/Cell cycle control phosphatase JW0492 ECK0497 b0504 ybbS ybbS glxA1 -!- allS 11.49 19.79 34.07 36.82 1.028 0.865 1.246 1.438 35.43 29.84 42.96 49.59 34.475 7.8 pr transcriptional activator of the allD operon Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW0494 ECK0499 b0506 allR allR gclR -!- glxA3 -!- ybbU 25.19 75.63 52.87 60.9 1.696 1.435 2.343 2.574 49.6 41.97 68.52 75.24 29.237 6.68 r DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix JW0495 ECK0500 b0507 gcl gcl 8.22 25.93 23.79 55.35 1.257 1 1.415 1.539 81.3 64.67 91.48 99.5 64.66 6.08 e glyoxylate carboligase Cytoplasmic 52467; DHS-like NAD/FAD-binding domain -!- 52518; Thiamin diphosphate-binding fold (THDP-binding) JW0496 ECK0501 b0508 hyi hyi gip -!- ybbG 28.85 31.71 70.24 69.99 1.431 1.8 1.312 1.443 42 52.81 38.51 42.34 29.343 6.02 e hydroxypyruvate isomerase Cytoplasmic 51658; Xylose isomerase-like JW0504 ECK0509 b0516 allC allC ylbB -!- glxB7 15.84 47.33 35.08 76.22 0.685 0.67 0.821 0.671 31.28 30.57 37.47 30.6 45.638 5.73 e allantoate amidohydrolase Cytoplasmic "53187; Zn-dependent exopeptidases -!- 55031; Carboxypeptidase G2, dimerisation domain" JW0505 ECK0510 b0517 allD allD glxB8 -!- yibC -!- ylbC 14.46 35.32 71.06 80.85 0.606 0.654 0.516 0.693 23 24.79 19.58 26.27 37.927 6.32 e ureidoglycolate dehydrogenase Cytoplasmic JW0509 ECK0513 b0520 ylbF ylbF 6 21.59 38.6 25.35 2.195 1.926 2.048 2.316 64.95 56.97 60.58 68.52 29.582 10.19 o conserved protein Cytoplasmic JW0510 ECK0514 b0521 ybcF ybcF arcC 8.54 15.06 49.98 74 2.076 1.759 1.976 2.126 65.6 55.59 62.44 67.17 31.601 5.52 pe predicted carbamate kinase Cytoplasmic 53633; Carbamate kinase-like JW0513 ECK0517 b0524 lpxH lpxH ybbF 17.56 23.7 54.73 109.93 1.711 1.587 1.735 1.477 45.99 42.66 46.64 39.7 26.875 8.06 e "UDP-2,3-diacylglucosamine pyrophosphatase" Cytoplasmic 56300; Metallo-dependent phosphatases JW0525 ECK0530 b0537 intD intD int 20.49 34.6 22.28 62.67 1.05 1.123 0.909 0.884 47.34 50.62 40.97 39.85 45.073 10.31 h DLP12 prophage; predicted integrase Cytoplasmic 56349; DNA breaking-rejoining enzymes JW0526 ECK0531 b0539 ybcC ybcC 11.31 13.86 14.53 143.84 6.283 5.488 6.204 6.591 65.95 57.61 65.12 69.18 10.496 7.41 h DLP12 prophage; predicted exonuclease Cytoplasmic 52980; Restriction endonuclease-like JW0532 ECK0535 b0544 ybcK ybcK 4.73 16.39 37.32 51.51 0.608 0.505 0.571 0.561 34.93 29.04 32.81 32.23 57.483 9.5 h DLP12 prophage; predicted recombinase Cytoplasmic 53041; Resolvase-like JW0539 ECK0543 b0551 ybcQ ybcQ 28.02 25.8 37.79 77.4 4.051 3.745 4.513 4.32 57.37 53.03 63.91 61.18 14.161 7.15 h DLP12 prophage; predicted antitermination protein Cytoplasmic JW0551 ECK0554 b0562 ybcY ybcY 37.65 57.29 108.02 79.72 0.753 0.855 0.81 0.817 15.9 18.05 17.11 17.25 21.107 7.42 h DLP12 prophage; predicted SAM-dependent methyltransferase Cytoplasmic 53335; S-adenosyl-L-methionine-dependent methyltransferases JW0555 ECK0558 b0566 envY envY 24.35 51.79 53.24 125.79 0.279 0.279 0.363 0.265 8.09 8.08 10.53 7.69 29.003 9.73 r DNA-binding transcriptional activator Cytoplasmic 46689; Homeodomain-like JW0570 ECK0573 b0581 ybdK ybdK 9.45 21.91 61.11 114.37 1.304 1.014 1.671 0.905 54.32 42.25 69.57 37.67 41.646 6.14 e gamma-glutamyl:cysteine ligase Cytoplasmic 1R8G JW0576 ECK0577 b0585 fes fes 18.99 29.8 60.7 79.67 0.743 0.774 0.849 0.825 31.61 32.92 36.11 35.1 42.527 6.69 e enterobactin/ferric enterobactin esterase Cytoplasmic 53474; alpha/beta-Hydrolases JW0578 ECK0579 b0586 entF entF 59.18 41.34 51.61 76.08 0.043 0.049 0.05 0.031 6.11 6.95 7.13 4.36 141.81 4.99 e "enterobactin synthase multienzyme complex component, ATP-dependent" Cytoplasmic 53474; alpha/beta-Hydrolases -!- 56801; Firefly luciferase-like JW0580 ECK0581 b0588 fepC fepC 20.98 28.65 97.4 80.59 2.334 1.913 1.965 1.967 69.44 56.93 58.47 58.52 29.755 6.67 t iron-enterobactin transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW0592 ECK0593 b0599 ybdH ybdH 5.79 23.12 69.86 69.27 0.915 0.68 0.897 0.653 35.74 26.57 35.03 25.52 39.05 6.2 pe predicted oxidoreductase Cytoplasmic 56796; Dehydroquinate synthase-like JW0593 ECK0594 b0600 ybdL ybdL 23.28 40.45 71.8 99.82 0.612 0.563 0.853 0.641 26.26 24.16 36.6 27.51 42.918 6.23 e "methionine aminotransferase, PLP-dependent" Cytoplasmic 1U08 53383; PLP-dependent transferases JW0595 ECK0596 b0602 ybdN ybdN 15.24 25.81 66.23 75.67 0.083 0.095 0.126 0.091 3.96 4.54 6 4.33 47.785 7.86 d conserved protein Cytoplasmic 52402; Adenine nucleotide alpha hydrolases JW0596 ECK0597 b0603 ybdO ybdO 8.18 16.99 53.47 67.04 0.534 0.481 0.518 0.385 18.37 16.54 17.8 13.25 34.366 7.78 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW0601 ECK0602 b0608 ybdR ybdR 40.31 42.66 82.44 89.7 0.586 0.708 0.911 0.81 25.86 31.22 40.2 35.76 44.133 6.54 pe "predicted oxidoreductase, Zn-dependent and NAD(P)-binding" Cytoplasmic 50129; GroES-like -!- 51735; NAD(P)-binding Rossmann-fold domains JW0605 ECK0606 b0613 citG citG ybdT 8.56 20.87 45.75 38.23 3.558 1.982 2.952 1.781 112.46 62.66 93.31 56.28 31.61 6.69 e triphosphoribosyl-dephospho-CoA transferase Cytoplasmic JW0608 ECK0609 b0616 citE citE ybdW 28.54 34.54 80.97 77.7 0.979 0.977 1.589 1.003 32.37 32.32 52.55 33.16 33.071 6.23 e "citrate lyase, citryl-ACP lyase (beta) subunit" Cytoplasmic 51621; Phosphoenolpyruvate/pyruvate domain JW0621 ECK0619 b0626 ybeM ybeM 13.8 25.9 61.01 70.88 2.714 2.59 3.015 2.009 55.54 53 61.7 41.11 20.463 8.36 pe "predicted C-N hydrolase superfamily, NAD(P)-binding amidase/nitrilase" Cytoplasmic 56317; Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase JW0623 ECK0621 b0628 lipA lipA lip 25.67 40.48 73.89 128.77 1 1.124 1.205 0.623 36.05 40.52 43.44 22.44 36.043 8.03 e lipoate synthase Cytoplasmic JW0624 ECK0622 b0629 ybeF ybeF cde 30.16 34.93 72.07 107.23 0.583 0.712 0.819 0.532 20.96 25.56 29.42 19.13 35.922 6.48 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW0631 ECK0629 b0636 ybeA ybeA 17 28.07 53.02 40.39 3.131 2.716 2.967 3.103 54.24 47.05 51.4 53.77 17.326 9.47 o conserved protein Cytoplasmic 1NS5 JW0640 ECK0638 b0645 ybeR ybeR 10.03 22.71 51.28 19.49 0.8 1.035 1.054 1.284 22.16 28.67 29.19 35.56 27.7 5.69 o predicted protein Cytoplasmic JW0643 ECK0641 b0648 ybeU ybeU 20.27 25.57 31.4 61.73 0.58 1.697 1.71 1.96 15.65 45.79 46.15 52.91 26.99 6.01 pe predicted tRNA ligase Cytoplasmic JW0659 ECK0654 b0662 ubiF ubiF yleB 11.61 27.6 30.87 49.53 0.876 1.032 0.844 1.077 37.6 44.28 36.21 46.22 42.914 7.42 e "2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol oxygenase" Cytoplasmic 51905; FAD/NAD(P)-binding domain JW0661 ECK0663 b0675 nagD nagD 12.69 14.58 101.8 28.05 2.519 2.813 2.593 2.677 68.33 76.31 70.35 72.63 27.13 6.07 e UMP phosphatase Cytoplasmic 56784; HAD-like JW0664 ECK0666 b0678 nagB nagB glmD 38.67 66.21 97.34 91.86 2.169 1.619 1.507 1.797 64.53 48.15 44.82 53.46 29.748 7.09 e glucosamine-6-phosphate deaminase Cytoplasmic 52512; Glucosamine 6-phosphate deaminase/isomerase JW0666 ECK0668 b0680 glnS glnS 53.23 91.52 71.14 65.82 0.294 0.742 0.513 0.499 18.65 47.05 32.51 31.66 63.411 6.23 e glutamyl-tRNA synthetase Cytoplasmic 1O0C 50715; Ribosomal protein L25-like -!- 52374; Nucleotidylyl transferase JW0674 ECK0675 b0687 seqA seqA 29.12 31.7 38.27 30.13 2.462 2.908 1.871 3.077 49.97 59.03 37.98 62.47 20.3 9.35 cp regulatory protein for replication initiation Cytoplasmic JW0680 ECK0681 b0693 speF speF 24.79 50.71 62.82 86.62 0.297 0.347 0.366 0.403 24.49 28.53 30.11 33.17 82.324 5.83 e "ornithine decarboxylase isozyme, inducible" Cytoplasmic 53383; PLP-dependent transferases -!- 55904; Ornithine decarboxylase C-terminal domain JW0692 ECK0691 b0703 ybfO ybfO 6.31 18.54 83.94 56.96 0.275 0.269 0.257 0.311 15.2 14.86 14.18 17.18 55.182 7.78 h "conserved protein, rhs-like" Cytoplasmic JW0695 ECK0694 b0705 ybfL ybfL 21.64 53.22 69.24 85.61 1.348 1.157 0.482 1.456 53.99 46.34 19.29 58.28 40.041 7.74 su predicted transposase (pseudogene) Cytoplasmic JW0696 ECK0695 b0706 ybfD ybfD 35.69 84.51 74.99 109.14 1.713 1.304 1.254 0.985 49.39 37.59 36.15 28.39 28.836 6.29 d conserved protein Cytoplasmic JW0697 ECK0696 b0707 ybgA ybgA tkp 20.3 25.71 42.52 76.12 1.94 1.964 2.03 1.414 39.2 39.67 41.02 28.56 20.205 10.17 o conserved protein Cytoplasmic JW0698 ECK0697 b0708 phr phr phrB 4.47 17.33 64.95 46.75 0.674 0.581 0.727 0.639 36.12 31.16 38.99 34.24 53.619 7.32 e "deoxyribodipyrimidine photolyase, FAD-binding" Cytoplasmic 1DNP 48173; FAD-binding (C-terminal) domain of DNA photolyase -!- 52425; N-terminal domain of DNA photolyase JW0700 ECK0699 b0710 ybgI ybgI 12.77 56.1 72.56 86.87 2.952 1.805 2.262 1.986 79.3 48.49 60.76 53.34 26.858 5.73 d conserved metal-binding protein Cytoplasmic JW0701 ECK0700 b0711 ybgJ ybgJ 51.88 98.91 121.23 125.38 0.402 0.447 0.436 0.302 9.62 10.69 10.43 7.23 23.916 6.08 pe predicted enzyme subunit Cytoplasmic JW0702 ECK0701 b0712 ybgK ybgK 2.21 2.4 44 3.93 3.165 3.08 2.856 2.947 108.74 105.82 98.14 101.26 34.359 8.54 pe predicted enzyme subunit Cytoplasmic "55239; RuBisCO, small subunit" JW0703 ECK0702 b0713 ybgL ybgL 1.67 3.68 51.75 10.63 4.718 4.401 4.277 5.549 121.59 113.43 110.23 143 25.773 6.55 pe predicted lactam utilization protein Cytoplasmic JW0710 ECK0709 b0720 gltA gltA glut -!- icdB -!- gluT 4.69 5.45 84.6 56.88 1.828 1.442 0.815 1.348 87.67 69.15 39.09 64.68 47.969 6.65 e citrate synthase Cytoplasmic 1K3P 48256; Citrate synthase JW0713 ECK0712 b0723 sdhA sdhA dhsA 17.15 12.19 70.23 44.03 1.547 1.302 1.233 1.887 99.54 83.79 79.35 121.42 64.355 6.18 c "succinate dehydrogenase, flavoprotein subunit" Cytoplasmic 1NEN 46977; Succinate dehydrogenase/fumarate reductase C-terminal domain -!- 51905; FAD/NAD(P)-binding domain -!- 56425; Succinate dehydrogenase/fumarate reductase catalytic domain JW0715 ECK0714 b0726 sucA sucA lys -!- met -!- lys+met 7.45 6.14 23.79 108.2 0.841 0.727 0.217 0.398 88.22 76.28 22.81 41.77 104.959 6.25 e "2-oxoglutarate decarboxylase, thiamin-requiring" Cytoplasmic 52518; Thiamin diphosphate-binding fold (THDP-binding) JW0721 ECK0720 b0732 mngB mngB ybgG 7.16 11.27 9.57 89.17 0.229 0.216 0.215 0.393 22.9 21.55 21.48 39.3 99.897 5.62 e alpha-mannosidase Cytoplasmic 69898; Golgi alpha-mannosidase II JW0742 ECK0748 b0759 galE galE galD 8.11 14.86 92.69 18.54 1.679 1.866 1.572 1.593 62.51 69.45 58.52 59.3 37.228 6.39 e UDP-galactose-4-epimerase Cytoplasmic 2UDP 51735; NAD(P)-binding Rossmann-fold domains JW0749 ECK0755 b0766 ybhA ybhA modD 2.33 4.74 62.47 21.06 6.204 5.885 5.236 5.502 187.18 177.56 157.98 166 30.169 6.03 pe predicted hydrolase Cytoplasmic 56784; HAD-like JW0757 ECK0763 b0774 bioA bioA 16.34 24.07 66.9 78.15 1.049 0.943 1.102 0.678 49.62 44.59 52.12 32.07 47.282 5.99 e "7,8-diaminopelargonic acid synthase, PLP-dependent" Cytoplasmic 1QJ5 53383; PLP-dependent transferases JW0759 ECK0765 b0776 bioF bioF 9.69 14.91 75.56 35.52 1.13 1.048 0.891 0.669 46.96 43.57 37.04 27.82 41.557 7.34 e 8-amino-7-oxononanoate synthase Cytoplasmic 53383; PLP-dependent transferases JW0760 ECK0766 b0777 bioC bioC 6.68 14.74 34.11 19.13 1.602 1.423 1.344 1.484 45.26 40.21 37.99 41.92 28.259 8.61 pe "predicted methltransferase, enzyme of biotin synthesis" Cytoplasmic 53335; S-adenosyl-L-methionine-dependent methyltransferases JW0761 ECK0767 b0778 bioD bioD 26.48 45.54 66.8 80.19 1.769 1.676 1.816 1.547 42.65 40.41 43.79 37.31 24.112 6.63 e dethiobiotin synthetase Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW0762 ECK0768 b0779 uvrB uvrB dar-1 -!- dar-6 10.1 43.86 32.65 79.58 0.28 0.127 0.244 0.233 21.34 9.69 18.54 17.75 76.126 5.18 cp "excinulease of nucleotide excision repair, DNA damage recognition component" Cytoplasmic "46600; C-terminal, UvrC-binding domain of UvrB -!- 52540; P-loop containing nucleotide triphosphate hydrolases" JW0763 ECK0769 b0780 ybhK ybhK 27.06 39.04 91.54 102.18 1.048 1.155 1.138 0.892 34.34 37.84 37.27 29.22 32.754 6.65 pe predicted transferase with NAD(P)-binding Rossmann-fold domain Cytoplasmic 51735; NAD(P)-binding Rossmann-fold domains JW0764 ECK0770 b0781 moaA moaA bisA -!- chlA -!- chlA1 -!- narA 8.43 24.7 77.61 56.4 1.18 0.983 1.239 1.08 44.03 36.69 46.24 40.31 37.317 8.1 e molybdopterin biosynthesis protein A Cytoplasmic JW0772 ECK0778 b0789 ybhO ybhO 14.17 21.61 38.92 65.88 1.298 1.214 1.095 0.676 61.79 57.76 52.13 32.19 47.596 8.88 e cardiolipin synthase 2 Cytoplasmic 56024; Phospholipase D/nuclease JW0773 ECK0779 b0790 ybhP ybhP 6.69 14.29 41.03 28.44 2.229 2.079 1.919 2.107 64.12 59.81 55.22 60.6 28.77 7.2 pe predicted DNase Cytoplasmic 56219; DNase I-like JW0784 ECK0788 b0799 dinG dinG rarB 4.28 3.14 6.19 48.79 0.328 0.562 0.455 0.691 26.67 45.72 37 56.21 81.366 7.74 e ATP-dependent DNA helicase Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW0785 ECK0789 b0800 ybiB ybiB 7.64 20.24 73.35 65.35 1.314 1.173 1.633 1.488 46.03 41.07 57.19 52.09 35.015 7.05 pe predicted transferase/phosphorylase Cytoplasmic 47648; Pyrimidine nucleoside phosphorylase N-terminal domain -!- 52418; Pyrimidine nucleoside phosphorylase central domain JW0786 ECK0790 b0801 ybiC ybiC 11.9 32.9 43.97 92.5 2.976 2.007 2.643 2.649 115.65 78 102.72 102.96 38.862 6.32 pe predicted dehydrogenase Cytoplasmic JW0805 ECK0811 b0821 ybiU ybiU 33.62 36.58 72.44 88.73 0.777 1.013 1.222 0.824 36.74 47.89 57.76 38.98 47.277 6.04 o predicted protein Cytoplasmic JW0822 ECK0828 b0838 yliJ yliJ 7.81 9.31 28.02 31.9 3.313 3.285 3.318 3.193 78.47 77.79 78.57 75.61 23.682 6.09 pe predicted glutathione S-transferase Cytoplasmic "47616; Glutathione S-transferases, C-terminal domain -!- 52833; Thioredoxin-like" JW0824 ECK0830 b0840 deoR deoR nucR 6.03 11.42 66.57 26.6 1.496 1.252 1.516 1.846 42.66 35.72 43.25 52.65 28.525 7.86 r DNA-binding transcriptional repressor Cytoplasmic 47413; lambda repressor-like DNA-binding domains JW0836 ECK0843 b0852 rimK rimK nek 2.72 4.02 61.36 16.57 2.679 3.17 2.979 2.62 86.82 102.75 96.52 84.91 32.407 8.08 s ribosomal protein S6 modification protein Cytoplasmic 56059; Glutathione synthetase ATP-binding domain-like JW0843 ECK0850 b0859 rumB rumB ybjF 3.02 4.97 42.07 48.34 2.568 2.392 1.818 1.333 107.64 100.27 76.22 55.88 41.913 7.34 e 23S rRNA m(5)U747 methyltransferase Cytoplasmic 53335; S-adenosyl-L-methionine-dependent methyltransferases JW0848 ECK0855 b0864 artP artP 23.38 36.73 95.07 63.94 2.849 2.45 3.124 2.419 76.91 66.14 84.34 65.31 26.995 6.99 t arginine transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW0854 ECK0861 b0870 ltaE ltaE ybjU -!- ltaA 4.04 5.59 61.95 71.14 5.153 4.31 4.903 2.282 187.86 157.14 178.76 83.18 36.455 6.45 e "L-allo-threonine aldolase, PLP-dependent" Cytoplasmic 53383; PLP-dependent transferases JW0855 ECK0862 b0871 poxB poxB 6.62 18.13 42.23 79.5 1.982 1.377 1.617 2.59 122.76 85.3 100.15 160.45 61.946 6.21 e "pyruvate dehydrogenase (pyruvate oxidase), thiamin-dependent, FAD-binding" Cytoplasmic 52467; DHS-like NAD/FAD-binding domain -!- 52518; Thiamin diphosphate-binding fold (THDP-binding) JW0860 ECK0867 b0876 ybjD ybjD 1.79 4.41 15.01 13.02 0.475 0.433 0.463 0.4 30.18 27.54 29.43 25.44 63.546 9.81 d conserved protein with nucleoside triphosphate hydrolase domain Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW0861 ECK0868 b0877 ybjX ybjX 4.41 10.54 19.55 28.47 7.092 6.377 6.212 7.59 271.87 244.45 238.14 290.94 38.334 9.88 o conserved protein Cytoplasmic JW0868 ECK0876 b0885 aat aat ycaA 6.14 12.51 84.29 25.23 4.37 3.451 3.57 3.777 116.23 91.79 94.96 100.44 26.596 7.54 e leucyl/phenylalanyl-tRNA-protein transferase Cytoplasmic JW0876 ECK0884 b0893 serS serS 21.32 24.96 67.27 66.09 1.983 1.523 3.058 4.335 95.87 73.62 147.88 209.61 48.355 5.73 e "seryl-tRNA synthetase, also charges selenocysteinyl-tRNA with serine" Cytoplasmic 46589; A class II aminoacyl-tRNA synthetase N-domain -!- 55681; Class II aaRS and biotin synthetases JW0878 ECK0886 b0895 dmsB dmsB 13.53 34.64 48.9 109.79 4.08 3.703 3.754 3.077 93.22 84.6 85.77 70.3 22.847 6.85 e "dimethyl sulfoxide reductase, anaerobic, subunit B" Cytoplasmic 54862; 4Fe-4S ferredoxins JW0883 ECK0891 b0900 ycaN ycaN 6.45 4.48 24.39 26.39 1.322 3.602 4.572 2.853 45.29 123.4 156.64 97.73 34.258 6.93 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW0890 ECK0898 b0907 serC serC pdxC -!- pdxF 3.05 4.21 59.49 14.92 5.315 4.748 6.06 5.017 211.19 188.67 240.78 199.37 39.736 6.09 e 3-phosphoserine/phosphohydroxythreonine aminotransferase Cytoplasmic 1BJO 53383; PLP-dependent transferases JW0895 ECK0903 b0912 ihfB ihfB himD -!- hip 11.43 21.06 10.97 117.27 10.797 10.657 11.916 12.464 114.95 113.45 126.86 132.69 10.646 10.09 r "integration host factor (IHF), DNA-binding protein, beta subunit" Cytoplasmic 1OWG 47729; IHF-like DNA-binding proteins JW0899 ECK0907 b0916 ycaQ ycaQ 2.03 3.59 44.19 14.36 2.04 2.118 2.29 2.64 97.13 100.84 109.03 125.74 47.621 8.77 o conserved protein Cytoplasmic JW0902 ECK0910 b0919 ycbJ ycbJ 3.44 4.09 57.69 14.13 4.779 5.315 5.549 4.451 164.67 183.12 191.17 153.36 34.453 7.56 d conserved protein Cytoplasmic 56112; Protein kinase-like (PK-like) JW0916 ECK0924 b0933 ssuB ssuB ycbE 28.55 41.25 68.76 63.06 2.123 1.765 2.455 1.753 58.82 48.92 68.04 48.57 27.71 8.22 t alkanesulfonate transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW0928 ECK0936 b0945 pyrD pyrD 9.73 11.16 69.85 64.45 1.138 1.292 1.131 0.929 41.8 47.45 41.54 34.11 36.739 8.17 e "dihydro-orotate oxidase, FMN-linked" Cytoplasmic 51395; FMN-linked oxidoreductases JW0931 ECK0939 b0948 ycbY ycbY 12.09 22.5 52.02 84.63 0.139 0.15 0.112 0.127 10.96 11.78 8.83 9.97 78.79 9.21 pe predicted methyltransferase Cytoplasmic 53335; S-adenosyl-L-methionine-dependent methyltransferases JW0993 ECK0999 b1008 ycdI ycdI 13.04 20.44 47.06 26.74 2.711 2.342 2.254 2.355 58.42 50.45 48.57 50.74 21.547 7.26 pe predicted oxidoreductase Cytoplasmic 55469; NADH oxidase/flavin reductase JW0994 ECK1000 b1009 rarA rarA ycdJ 21.38 28.14 77.26 80.69 1.095 1.131 1.104 0.892 31.61 32.66 31.86 25.76 28.869 6.42 pe predicted hydrolase Cytoplasmic 53474; alpha/beta-Hydrolases JW0997 ECK1003 b1012 ycdM ycdM 10.96 17.28 45.63 107.81 0.747 0.6 0.582 0.465 31.49 25.3 24.55 19.62 42.166 5.72 pe predicted monooxygenase Cytoplasmic 51679; Bacterial luciferase-like JW1005 ECK1010 b1020 phoH phoH psiH 67.12 27.51 113.09 93.96 0.105 0.405 0.182 0.193 4.12 15.89 7.13 7.57 39.235 8.57 d conserved protein with nucleoside triphosphate hydrolase domain Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW1023 ECK1026 b1040 csgD csgD 25.11 35.78 91.22 126.24 1.983 1.603 1.024 1.723 49.43 39.95 25.52 42.93 24.922 9.84 r DNA-binding transcriptional activator in two-component regulatory system Cytoplasmic "46894; C-terminal, effector domain of the bipartite response regulators" JW1049 ECK1047 b1062 pyrC pyrC 11.2 20.54 85.49 56.57 1.5 1.485 1.772 1.188 58.19 57.61 68.75 46.08 38.787 6.24 e dihydro-orotase Cytoplasmic 51556; Metallo-dependent hydrolases JW1081 ECK1081 b1095 fabF fabF cvc -!- fabJ -!- vtr -!- vtrB 9.27 30.34 46.47 78.27 1.453 0.808 1.256 1.416 62.48 34.75 54 60.87 42.999 6.28 e 3-oxoacyl-[acyl-carrier-protein] synthase II Cytoplasmic 53901; Thiolase-like JW1082 ECK1082 b1096 pabC pabC 15.83 24.56 79.77 65.34 1.07 1.206 1.487 1.361 31.76 35.8 44.15 40.41 29.684 6.88 e 4-amino-4-deoxychorismate lyase component of para-aminobenzoate synthase multienzyme complex Cytoplasmic 1I2L 56752; D-amino acid aminotransferase-like PLP-dependent enzymes JW1092 ECK1092 b1106 ycfN ycfN 24.07 112.02 76.15 76.64 1.108 1.044 1.193 1.103 35.88 33.8 38.63 35.72 32.379 10.39 e thiamin kinase Cytoplasmic 56112; Protein kinase-like (PK-like) JW1093 ECK1093 b1107 nagZ nagZ ycfO 21.4 29.66 92.56 51.46 1.037 1.059 1.155 1.667 38.93 39.78 43.38 62.6 37.556 6.36 e beta N-acetyl-glucosaminidase Cytoplasmic 51445; (Trans)glycosidases JW1105 ECK1105 b1119 ycfX ycfX 27.78 37.98 91.38 89.03 1.333 1.204 1.447 1.572 43.99 39.75 47.76 51.87 33.003 5.96 pr predicted DNA-binding transcriptional regulator Cytoplasmic 53067; Actin-like ATPase domain JW1123 ECK1123 b1137 ymfD ymfD 15.64 25.31 63.99 127.3 0.691 0.66 0.792 0.597 17.37 16.59 19.91 15.01 25.13 9.19 h e14 prophage; predicted SAM-dependent methyltransferase Cytoplasmic 53335; S-adenosyl-L-methionine-dependent methyltransferases JW1126 ECK1126 b1140 intE intE int(Lambda) -!- ycfI 14.04 32.06 20.31 34.95 1.25 1.13 1.206 1.32 53.49 48.37 51.6 56.49 42.784 10.6 h e14 prophage; predicted integrase Cytoplasmic 56349; DNA breaking-rejoining enzymes JW1133 ECK1133 b1147 ymfL ymfL 14.52 25.88 28.04 22.93 3.011 2.577 2.525 3.069 62.21 53.25 52.18 63.43 20.665 5.72 h e14 prophage; predicted DNA-binding transcriptional regulator Cytoplasmic JW1135 ECK1135 b1149 ymfN ymfN 7.33 17.07 22.59 62.41 1.418 1.515 2.085 1.212 72.02 76.95 105.93 61.56 50.805 5.29 h e14 prophage; predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix JW1137 ECK1137 b1151 ymfO ymfO 9.03 15.23 52.14 32.86 2.756 2.379 2.341 2.7 48.5 41.87 41.19 47.51 17.596 8.47 h e14 prophage; conserved protein Cytoplasmic JW1139 ECK1139 b1153 ymfQ ymfQ 12.19 19.27 37.67 39.77 2.992 2.312 3.773 2.577 64.67 49.97 81.56 55.7 21.616 6.27 h e14 prophage; conserved protein Cytoplasmic JW1140 ECK1140 b1154 ycfK ycfK 26.08 38.07 39.68 94.52 3.518 2.545 3.475 3.415 77.38 55.96 76.42 75.11 21.994 6.81 h e14 prophage; predicted protein Cytoplasmic JW1144 ECK1144 b1158 pin pin 27.19 34.56 30.09 61.18 2.062 2.079 1.797 1.95 42.39 42.75 36.96 40.1 20.56 10.56 h e14 prophage; site-specific DNA recombinase Cytoplasmic 46689; Homeodomain-like -!- 53041; Resolvase-like JW1150 ECK1150 b1163 ycgF ycgF 14.09 25.21 56.37 104.13 0.836 0.833 0.775 0.676 37.81 37.66 35.04 30.59 45.235 5.35 pe predicted FAD-binding phosphodiesterase Cytoplasmic 51395; FMN-linked oxidoreductases JW1169 ECK1168 b1180 ycgM ycgM 25.53 31.57 71.2 92.2 3.227 3.199 4.329 3.54 76.43 75.76 102.55 83.85 23.687 6.6 pe predicted isomerase/hydrolase Cytoplasmic 1NR9 56529; FAH JW1173 ECK1172 b1184 umuC umuC uvm 5.2 20.87 67.02 70.78 0.686 0.698 0.697 0.496 32.7 33.27 33.22 23.65 47.641 9.13 e "DNA polymerase V, subunit C" Cytoplasmic 56672; DNA/RNA polymerases JW1177 ECK1176 b1188 ycgB ycgB 4.79 23.6 35.56 54.02 0.844 0.703 0.954 0.763 51.28 42.71 57.92 46.37 60.747 6.02 o conserved protein Cytoplasmic JW1178 ECK1177 b1189 dadA dadA dadR 8.7 29.5 93.45 87.34 0.417 0.404 0.435 0.443 19.84 19.19 20.66 21.06 47.558 6.8 e D-amino acid dehydrogenase Cytoplasmic "51971; Nucleotide-binding domain -!- 54373; FAD-linked reductases, C-terminal domain" JW1179 ECK1178 b1190 dadX dadX alnA -!- alnB -!- dadB 1.85 11.18 36.14 24.81 2.097 1.753 1.884 1.278 81.38 68.04 73.12 49.6 38.808 7.35 e "alanine racemase 2, PLP-binding" Cytoplasmic "50621; Alanine racemase-like, C-terminal domain -!- 51419; PLP-binding barrel" JW1181 ECK1180 b1192 ldcA ldcA ycgQ 7.25 16.54 58.22 46.78 2.369 2.264 3.58 3.157 79.43 75.93 120.06 105.88 33.536 6.61 e "L,D-carboxypeptidase A" Cytoplasmic JW1193 ECK1190 b1202 ycgV ycgV 12.78 20.88 10.7 142.18 0.066 0.069 0.037 0.043 6.54 6.87 3.73 4.32 99.566 5.24 pf predicted adhesin Cytoplasmic 51126; Pectin lyase-like JW1198 ECK1195 b1207 prsA prsA dnaR -!- prs 16.68 22.9 74.03 53.91 1.761 1.453 1.363 1.303 60.18 49.66 46.58 44.52 34.176 6.09 e phosphoribosylpyrophosphate synthase Cytoplasmic 53271; PRTase-like JW1201 ECK1198 b1210 hemA hemA gtrA 24.93 40.73 51.99 113.19 1.455 1.764 1.691 1.477 67.3 81.57 78.23 68.33 46.252 5.95 e glutamyl tRNA reductase Cytoplasmic "51735; NAD(P)-binding Rossmann-fold domains -!- 69075; Glutamyl tRNA-reductase dimerization domain -!- 69742; Glutamyl tRNA-reductase catalytic, N-terminal domain" JW1206 ECK1203 b1215 kdsA kdsA 10.67 23.59 80.37 76.68 0.686 0.531 0.897 0.727 21.11 16.34 27.63 22.4 30.801 7.28 e 3-deoxy-D-manno-octulosonate 8-phosphate synthase Cytoplasmic 1PL9 51569; Aldolase JW1209 ECK1212 b1218 chaC chaC 26.76 49.19 72.51 64.31 0.546 0.598 0.54 0.647 14.43 15.78 14.25 17.09 26.408 6.17 r regulatory protein for cation transport Cytoplasmic JW1211 ECK1214 b1220 ychP ychP ychO 7.57 24.77 30.27 61.58 0.781 0.97 1.143 0.889 36.7 45.56 53.68 41.74 46.967 5.73 pf predicted invasin Cytoplasmic JW1215 ECK1218 b1224 narG narG chlC -!- narC 11.07 39.58 27.72 116.09 0.086 0.102 0.107 0.087 12.08 14.34 15.06 12.25 140.348 6.24 e "nitrate reductase 1, alpha subunit" Cytoplasmic 1Q16 "50692; ADC-like -!- 53706; Formate dehydrogenase/DMSO reductase, domains 1-3" JW1216 ECK1219 b1225 narH narH chlC 10.46 16.51 46.44 50.4 1.418 1.416 1.563 1.705 82.26 82.16 90.68 98.92 58.006 6.9 c "nitrate reductase 1, beta (Fe-S) subunit" Cytoplasmic 1SIW 54862; 4Fe-4S ferredoxins JW1222 ECK1229 b1234 rssA rssA ychK 2.63 12.46 69.18 42.1 0.565 0.572 0.634 0.545 19.4 19.62 21.75 18.71 34.321 7 o conserved protein Cytoplasmic JW1227 ECK1234 b1239 ychG ychG_2 21.43 42.15 52 86.23 0.909 0.913 1.001 0.988 20.17 20.27 22.22 21.92 22.195 10.46 su "predicted protein, C-ter fragment (pseudogene)" Cytoplasmic JW1238 ECK1240 b1246 oppD oppD 13.94 18.02 83.02 93.22 1.254 1.154 1.422 1.286 46.6 42.88 52.83 47.79 37.146 6.51 t oligopeptide transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW1239 ECK1241 b1247 oppF oppF 17.87 40.24 65.11 78.67 1.162 1.052 1.382 1.246 43.2 39.11 51.36 46.3 37.165 7.92 t oligopeptide transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW1254 ECK1256 b1262 trpC trpC 21.7 31.31 78.78 75.98 1.531 1.325 1.41 1.541 75.49 65.31 69.5 75.99 49.305 6.04 e fused indole-3-glycerolphosphate synthetase -!- N-(5-phosphoribosyl)anthranilate isomerase Cytoplasmic 1PII 51366; Ribulose-phoshate binding barrel -!- 51366; Ribulose-phoshate binding barrel JW1255 ECK1257 b1263 trpD trpD trpGD 14.83 29.66 87.47 91.73 0.21 0.245 0.239 0.246 11.91 13.89 13.59 13.99 56.816 6.38 e fused glutamine amidotransferase (component II) of anthranilate synthase -!- anthranilate phosphoribosyl transferase Cytoplasmic 52317; Class I glutamine amidotransferase-like -!- 47648; Pyrimidine nucleoside phosphorylase N-terminal domain -!- 52418; Pyrimidine nucleoside phosphorylase central domain JW1267 ECK1269 b1275 cysB cysB 8.85 15.63 49.83 53.22 1.863 2.257 1.339 1.944 67.3 81.51 48.37 70.21 36.12 7.97 r "DNA-binding transcriptional dual regulator, O-acetyl-L-serine-binding" Cytoplasmic 1AL3 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW1283 ECK1285 b1290 sapF sapF 18.22 23.62 36.23 46.21 0.961 1.014 1.161 1.14 29.36 30.96 35.46 34.83 30.548 10 pt predicted antimicrobial peptide transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW1284 ECK1286 b1291 sapD sapD trkE 20.74 24.63 47.6 58.05 1.43 1.247 1.268 1.619 53.81 46.94 47.73 60.93 37.635 9.4 pt predicted antimicrobial peptide transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW1293 ECK1295 b1300 puuC puuC aldH 7.16 23.53 60.85 90.18 1.249 1.03 1.552 1.479 66.65 54.96 82.82 78.92 53.36 6.18 e "gamma-Glu-gamma-aminobutyraldehyde dehydrogenase, NAD(P)H-dependent" Cytoplasmic 53720; ALDH-like JW1294 ECK1296 b1301 puuB puuB ycjA -!- ordL 12.06 19.38 81.29 71 0.714 0.728 0.932 0.852 33.62 34.31 43.9 40.15 47.122 7 e "gamma-Glu-putrescine oxidase, FAD/NAD(P)-binding" Cytoplasmic 51905; FAD/NAD(P)-binding domain JW1302 ECK1304 b1309 ycjM ycjM sucP 6.95 19.46 48.29 75.66 0.474 0.427 0.486 0.335 30.37 27.41 31.18 21.48 64.123 6.17 pe predicted glucosyltransferase Cytoplasmic 51445; (Trans)glycosidases JW1306 ECK1308 b1313 ycjQ ycjQ 13.71 8.92 62.42 31.13 1.744 1.967 2.057 1.898 66.57 75.09 78.53 72.46 38.172 6.3 pe "predicted oxidoreductase, Zn-dependent and NAD(P)-binding" Cytoplasmic 50129; GroES-like -!- 51735; NAD(P)-binding Rossmann-fold domains JW1311 ECK1313 b1318 ycjV ycjV 9.68 21.04 70.24 60.64 1.602 1.781 1.751 1.978 57.23 63.64 62.56 70.68 35.733 8.82 pt predicted sugar transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 50331; MOP-like -!- 52540; P-loop containing nucleotide triphosphate hydrolases JW1314 ECK1317 b1321 ycjX ycjX 8.66 19.88 59.23 82.2 1.018 1.051 1.004 0.904 53.51 55.27 52.76 47.51 52.563 8.43 d conserved protein with nucleoside triphosphate hydrolase domain Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW1318 ECK1321 b1325 ycjG ycjG ycjH 19.85 27.03 82.98 73.75 2.49 2.6 2.257 2.463 86.21 90.03 78.17 85.29 34.627 5.48 e L-Ala-D/L-Glu epimerase Cytoplasmic 51604; Enolase C-terminal domain-like -!- 54826; Enolase N-terminal domain-like JW1329 ECK1331 b1335 ogt ogt 4.16 10.57 44.57 19.14 3.394 2.725 3.829 3.109 65.04 52.22 73.37 59.57 19.163 8.7 e O-6-alkylguanine-DNA:cysteine-protein methyltransferase Cytoplasmic "46767; Methylated DNA-protein cysteine methyltransferase, C-terminal domain" JW1333 ECK1335 b1339 abgR abgR ydaK 3.66 16.69 20.41 18.42 2.87 2.149 2.533 2.171 97.64 73.11 86.21 73.86 34.028 8.08 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW1337 ECK1340 b1343 dbpA dbpA rhlC 15.71 22.15 50.94 102.95 1.043 0.981 0.882 0.831 51.23 48.2 43.35 40.86 49.142 7.81 e ATP-dependent RNA helicase specific for 23S rRNA Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW1347 ECK1350 b1352 kil kil ydaD 22.03 57.97 32.28 92.1 5.748 5.242 5.045 5.914 48.47 44.2 42.54 49.87 8.432 10.41 h "Rac prophage; inhibitor of ftsZ, killing protein" Cytoplasmic JW1354 ECK1357 b1359 ydaU ydaU 41.41 54.97 43.79 46.22 0.626 0.712 0.739 0.73 20.34 23.12 23.99 23.7 32.481 9.49 h Rac prophage; conserved protein Cytoplasmic JW1372 ECK1374 b1378 ydbK ydbK nifJ 22.78 43.48 9.93 61.21 0.09 0.09 0.127 0.134 11.64 11.63 16.33 17.24 128.677 5.67 pc fused predicted Fe-S subunit of pyruvate-flavodoxin oxidoreductase Cytoplasmic "52518; Thiamin diphosphate-binding fold (THDP-binding) -!- 52922; Transketolase C-terminal domain-like -!- 53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III -!- 54862; 4Fe-4S ferredoxins -!- 52518; Thiamin diphosphate-binding fold" JW1380 ECK1382 b1385 feaB feaB padA -!- ydbG 6.62 12.4 56.35 80.11 0.909 0.754 0.953 1.043 48.77 40.46 51.11 55.93 53.635 5.88 e phenylacetaldehyde dehydrogenase Cytoplasmic 53720; ALDH-like JW1382 ECK1384 b1387 maoC maoC paaZ -!- ydbN 22.58 6.83 22.29 78.64 0.33 0.62 0.499 0.802 24.04 45.2 36.41 58.5 72.927 6.36 e fused aldehyde dehydrogenase -!- enoyl-CoA hydratase Cytoplasmic 53720; ALDH-like JW1387 ECK1389 b1392 paaE paaE ydbR 23.41 31.4 71.54 96.48 2.212 2.027 1.717 1.749 86.89 79.61 67.44 68.69 39.277 6.68 pe predicted multicomponent oxygenase/reductase subunit for phenylacetic acid degradation Cytoplasmic "52343; Ferredoxin reductase-like, C-terminal NADP-linked domain -!- 54292; 2Fe-2S ferredoxin-like -!- 63380; Riboflavin synthase domain-like" JW1390 ECK1392 b1395 paaH paaH ydbU -!- hbdH 3.24 13.45 24.42 65.71 1.536 1.266 1.235 1.218 79.37 65.42 63.81 62.93 51.673 6.21 e 3-hydroxybutyryl-CoA dehydrogenase Cytoplasmic 48179; 6-phosphogluconate dehydrogenase C-terminal domain-like -!- 51735; NAD(P)-binding Rossmann-fold domains JW1392 ECK1394 b1397 paaJ paaJ ydbW 10.34 15.23 85.14 56.67 0.639 0.634 0.783 0.607 26.98 26.78 33.07 25.64 42.231 6.74 pe predicted beta-ketoadipyl CoA thiolase Cytoplasmic 53901; Thiolase-like JW1394 ECK1396 b1399 paaX paaX ydbY 22.52 23.76 66.49 55.78 0.51 0.489 0.398 0.49 17.97 17.24 14.04 17.28 35.262 7.93 r "DNA-binding transcriptional regulator, aryl-CoA responsive" Cytoplasmic 46785; Winged helix JW1402 ECK1398 b1405 ydbA ydbA_2 19.11 91.38 74.21 55.69 0.242 0.089 0.12 0.233 27.78 10.18 13.7 26.67 114.589 4.45 su "predicted outer membrane protein, C-ter fragment (pseudogene)" Cytoplasmic JW1407 ECK1403 b1410 ynbC ynbC 9.73 43.75 54.2 101.16 0.33 0.254 0.326 0.214 21.61 16.61 21.3 13.97 65.407 9.42 pe predicted hydrolase Cytoplasmic 53335; S-adenosyl-L-methionine-dependent methyltransferases -!- 53474; alpha/beta-Hydrolases JW1411 ECK1407 b1414 ydcF ydcF 46.99 66.3 100.86 104.61 0.542 0.592 0.683 0.54 16.08 17.55 20.26 16.02 29.673 6.17 o conserved protein Cytoplasmic JW1419 ECK1417 b1423 ydcJ ydcJ 11.56 21.07 69.99 81.33 0.992 0.843 1.185 0.982 50.59 42.98 60.39 50.08 50.982 5.71 o conserved protein Cytoplasmic JW1424 ECK1421 b1428 ydcK ydcK 9.05 31.21 23.8 78.88 0.658 0.621 0.781 0.608 23.56 22.24 27.96 21.77 35.804 5.49 pe predicted enzyme Cytoplasmic 51161; Trimeric LpxA-like enzymes JW1431 ECK1429 b1435 ydcP ydcP 11.57 38.03 61.56 90.84 0.13 0.14 0.158 0.118 9.42 10.19 11.47 8.57 72.64 7.06 pe predicted peptidase Cytoplasmic JW1434 ECK1433 b1439 ydcR ydcR 5.08 6.58 10.99 21.62 0.683 0.618 1.019 0.767 36 32.61 53.75 40.45 52.746 9.17 pr fused predicted DNA-binding transcriptional regulator -!- predicted amino transferase Cytoplasmic 46785; Winged helix -!- 53383; PLP-dependent transferases JW1436 ECK1435 b1441 ydcT ydcT 27.83 76.13 116.33 97.93 0.317 0.328 0.455 0.358 11.72 12.15 16.83 13.26 37.002 7.8 pt predicted spermidine/putrescine transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW1439 ECK1438 b1444 ydcW ydcW 9.96 24.77 43.99 66.3 1.146 0.883 1.621 1.148 58.17 44.84 82.29 58.3 50.774 6.08 e medium chain aldehyde dehydrogenase Cytoplasmic 53720; ALDH-like JW1449 ECK1448 b1454 yncG yncG 16.74 22.86 47.24 74.8 1.751 1.747 1.933 1.851 40.77 40.68 45.02 43.12 23.287 5.51 pe predicted enzyme Cytoplasmic "47616; Glutathione S-transferases, C-terminal domain -!- 52833; Thioredoxin-like" JW1451 ECK1450 b1456 rhsE rhsE 3.72 9.14 16.59 31.27 0.158 0.336 0.129 0.506 12.14 25.9 9.92 39.02 77.065 6.06 h rhsE element core protein RshE Cytoplasmic JW1455 ECK1454 b1460 ydcC ydcC 16.99 44.29 26.01 67.17 1.017 0.383 0.841 1.17 43.76 16.5 36.18 50.34 43.044 7.5 d conserved protein Cytoplasmic JW1462 ECK1461 b1467 narY narY chlZ 5.95 18.71 36.44 36.59 0.654 0.375 0.712 1.052 38.22 21.91 41.62 61.52 58.491 6.09 c "nitrate reductase 2 (NRZ), beta subunit" Cytoplasmic 54862; 4Fe-4S ferredoxins JW1467 ECK1465 b1471 yddK yddK 2.94 9.75 31.82 30.42 1.419 1.177 1.108 0.91 51.36 42.63 40.13 32.94 36.205 6.39 o predicted protein Cytoplasmic 52058; L domain-like JW1478 ECK1477 b1483 ddpF ddpF yddO 14.24 25.41 70.5 62.43 0.413 0.467 0.483 0.442 14.27 16.14 16.72 15.28 34.592 8.09 t D-Ala-D-Ala transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW1479 ECK1478 b1484 ddpD ddpD yddP 10.12 37.9 61.61 68.23 0.489 0.338 0.607 0.711 17.64 12.2 21.9 25.65 36.068 7.21 t D-Ala-D-Ala transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW1484 ECK1483 b1489 dos dos yddU 17.77 19.08 90.13 106.29 0.127 0.203 0.074 0.227 11.46 18.27 6.67 20.45 90.152 5.5 e "cAMP phosphodiesterase, heme-regulated" Cytoplasmic 55785; PYP-like sensor domain JW1488 ECK1487 b1493 gadB gadB 11.5 38.07 46.68 93.53 0.655 0.246 0.637 0.74 34.44 12.92 33.51 38.94 52.604 5.75 e "glutamate decarboxylase B, PLP-dependent" Cytoplasmic 1PMO 53383; PLP-dependent transferases JW1492 ECK1491 b1497 ydeM ydeM 12.06 28.51 37.04 100.68 0.35 0.183 0.332 0.424 15.57 8.14 14.79 18.87 44.483 7.95 pr conserved protein Cytoplasmic JW1495 ECK1494 b1501 ydeP ydeP 7.77 24.22 33.85 78.44 0.162 0.069 0.103 0.211 13.49 5.75 8.6 17.57 83.413 6.64 pe predicted oxidoreductase Cytoplasmic "50692; ADC-like -!- 53706; Formate dehydrogenase/DMSO reductase, domains 1-3" JW1499 ECK1498 b1505 ydeT ydeT 11.89 28.77 17.97 39.25 0.74 0.403 0.902 1.094 30.75 16.73 37.48 45.47 41.574 7.02 o predicted protein Cytoplasmic JW1502 ECK1502 b1509 ydeU ydeU 6.68 64.77 16.03 72.18 0.851 0.341 0.803 1.145 42.94 17.2 40.53 57.83 50.485 6.19 su "conserved protein, predicted pseudogene" Cytoplasmic 51126; Pectin lyase-like JW1504 ECK1504 b1511 ydeV ydeV 3.67 10.9 49.3 71.78 0.711 0.633 0.995 0.713 40.84 36.4 57.19 41 57.475 5.68 pe predicted sugar kinase Cytoplasmic 53067; Actin-like ATPase domain JW1505 ECK1505 b1512 ydeW ydeW 9.32 36.02 70.78 76 0.613 0.667 0.63 0.617 20.69 22.53 21.26 20.84 33.761 7.26 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix JW1506 ECK1506 b1513 ego ego lsrA -!- ydeX 15.98 25.29 63.69 56.82 0.907 0.765 0.942 0.74 50.58 42.67 52.55 41.26 55.766 7.59 t fused AI2 transporter subunits -!- ATP-binding components of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases -!- 52540; P-loop containing nucleotide triphosphate hydrolases JW1519 ECK1519 b1526 yneJ yneJ 34.72 55.48 80.51 109.74 0.569 0.515 0.531 0.411 18.48 16.7 17.22 13.35 32.452 7.08 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW1520 ECK1520 b1527 yneK yneK 20.16 19.79 53.67 73.2 0.314 0.297 0.335 0.309 13.42 12.72 14.34 13.23 42.802 6.94 o predicted protein Cytoplasmic JW1532 ECK1532 b1539 ydfG ydfG 72.86 96.73 85.27 92.86 2.845 2.791 3.009 2.691 77.43 75.96 81.9 73.24 27.219 6.41 e "L-allo-threonine dehydrogenase, NAD(P)-binding" Cytoplasmic 51735; NAD(P)-binding Rossmann-fold domains JW1535 ECK1535 b1542 ydfI ydfI 20.03 54.41 45.28 110.22 0.264 0.208 0.24 0.22 14.15 11.14 12.88 11.79 53.623 5.79 pe predicted mannonate dehydrogenase Cytoplasmic JW1538 ECK1538 b1545 pinQ pinQ ydfL 40.18 57.36 66.92 95.25 1.821 1.549 1.789 1.697 39.76 33.82 39.07 37.07 21.839 10.32 h Qin prophage; predicted site-specific recombinase Cytoplasmic 46689; Homeodomain-like -!- 53041; Resolvase-like JW1540 ECK1540 b1547 stfQ stfQ 18.32 42.57 37.77 104.3 0.757 0.741 0.943 0.888 24.91 24.37 31 29.19 32.882 8.23 h Qin prophage; predicted side tail fibre assembly protein Cytoplasmic JW1550 ECK1552 b1558 cspF cspF 15.96 17.59 16.19 104.52 4.1 3.768 4.228 4.685 30.98 28.48 31.95 35.41 7.558 10.34 h Qin prophage; cold shock protein Cytoplasmic 50249; Nucleic acid-binding proteins JW1571 ECK1573 b1579 intQ intQ 22.51 29.52 56.76 66.6 0.226 0.273 0.238 0.254 10.23 12.34 10.77 11.48 45.201 10.04 h Qin prophage; predicted defective integrase Cytoplasmic "47823; lambda integrase-like, N-terminal domain -!- 56349; DNA breaking-rejoining enzymes" JW1573 ECK1576 b1581 rspA rspA 4.32 15.99 47.3 22.06 1.223 1.274 1.508 1.666 56.15 58.51 69.27 76.52 45.919 6.11 pe predicted dehydratase Cytoplasmic 51604; Enolase C-terminal domain-like -!- 54826; Enolase N-terminal domain-like JW1586 ECK1589 b1594 dgsA dgsA mlc 25.17 30.63 60.97 75.34 0.917 0.977 1.069 1.087 40.59 43.24 47.3 48.13 44.27 6.22 r DNA-binding transcriptional repressor Cytoplasmic 46785; Winged helix JW1598 ECK1601 b1606 folM folM ydgB 21.51 38.87 116.61 72.7 2.18 2.03 1.98 2.231 57.4 53.46 52.14 58.76 26.331 8.35 e dihydrofolate reductase isozyme Cytoplasmic 51735; NAD(P)-binding Rossmann-fold domains JW1602 ECK1605 b1610 tus tus tau 6.27 18.16 66 37.27 1.324 1.223 1.294 1.38 47.36 43.76 46.27 49.35 35.769 10.14 f "inhibitor of replication at Ter, DNA-binding protein" Cytoplasmic 1ECR 56596; Replication terminator protein (Tus) JW1612 ECK1615 b1620 malI malI 11.17 21.87 37.84 52.24 1.598 1.342 2.11 2.036 58.48 49.12 77.2 74.48 36.589 7.36 r DNA-binding transcriptional repressor Cytoplasmic 47413; lambda repressor-like DNA-binding domains -!- 53822; Periplasmic binding protein-like I JW1614 ECK1617 b1622 malY malY 30.04 49.91 105.45 115.07 0.368 0.462 0.444 0.368 16.02 20.15 19.35 16.04 43.589 5.82 e "bifunctional beta-cystathionase, PLP-dependent -!- regulator of maltose regulon" Cytoplasmic 1D2F 53383; PLP-dependent transferases JW1615 ECK1618 b1623 add add 17.39 26.44 88.55 80.95 0.873 1.099 0.906 0.888 31.73 39.95 32.94 32.28 36.355 5.84 e adenosine deaminase Cytoplasmic 51556; Metallo-dependent hydrolases JW1639 ECK1643 b1647 ydhF ydhF 5.32 12.96 48.22 20.71 2.054 2.038 2.197 2.12 69.1 68.56 73.9 71.33 33.64 6.32 pe predicted oxidoreductase Cytoplasmic 51430; NAD(P)-linked oxidoreductase JW1651 ECK1655 b1659 ydhB ydhB 3.92 15.51 27.51 46.87 1.865 1.658 1.359 1.75 65.65 58.35 47.84 61.61 35.205 5.71 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW1653 ECK1657 b1661 cfa cfa cdfA 32.27 45.59 86.16 70.67 0.369 0.351 0.24 0.364 16.17 15.41 10.53 15.95 43.86 6.31 e cyclopropane fatty acyl phospholipid synthase (unsaturated-phospholipid methyltransferase) Cytoplasmic 53335; S-adenosyl-L-methionine-dependent methyltransferases JW1659 ECK1665 b1669 ydhT ydhT 26.76 40.9 69.17 105.37 0.966 0.961 1.089 1.096 28.33 28.16 31.91 32.12 29.314 6.82 d conserved protein Cytoplasmic 47986; DEATH domain JW1670 ECK1676 b1680 sufS sufS csdB -!- f406 -!- ynhB 6.66 10.5 67.79 53.41 0.936 0.878 0.794 0.803 41.56 38.98 35.26 35.65 44.39 6.28 e "selenocysteine lyase, PLP-dependent" Cytoplasmic 1I29 53383; PLP-dependent transferases JW1677 ECK1684 b1687 ydiJ ydiJ 27.3 13.06 42.46 92.1 0.035 0.204 0.05 0.135 3.91 23.03 5.69 15.23 113.138 6.98 pe predicted FAD-linked oxidoreductase Cytoplasmic "55103; FAD-linked oxidases, C-terminal domain -!- 56176; FAD-binding domain" JW1688 ECK1696 b1698 ydiR ydiR 16.74 39.07 32.04 114.54 0.585 0.484 0.715 0.567 19.74 16.33 24.12 19.12 33.737 7.52 pc "predicted electron transfer flavoprotein, FAD-binding" Cytoplasmic 52431; ETFP adenine nucleotide-binding domain-like -!- 52467; DHS-like NAD/FAD-binding domain JW1693 ECK1701 b1703 ydiA ydiA 22.47 21.98 65.31 64.03 0.609 1.314 1.475 1.248 18.99 40.96 46 38.9 31.178 6.75 d conserved protein Cytoplasmic 53850; Periplasmic binding protein-like II JW1694 ECK1702 b1704 aroH aroH 13.91 27.73 66.53 64.34 1.227 0.983 1.081 0.836 47.49 38.04 41.83 32.35 38.699 7.04 e "3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, tryptophan repressible" Cytoplasmic 51569; Aldolase JW1696 ECK1704 b1706 ydiU ydiU 1.16 14.72 44.59 43.27 1.066 1.097 0.977 0.917 57.92 59.58 53.08 49.81 54.322 5.94 o conserved protein Cytoplasmic JW1697 ECK1705 b1707 ydiV ydiV 31.56 47.67 83.55 80.26 0.383 0.788 0.765 0.754 10.34 21.29 20.66 20.36 27.016 6.3 o conserved protein Cytoplasmic JW1699 ECK1707 b1709 btuD btuD 17.65 18.15 68.99 40.76 1.298 2.698 3.193 2.93 35.12 73.02 86.42 79.28 27.063 9.87 t vitamin B12 transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 1L7V 52540; P-loop containing nucleotide triphosphate hydrolases JW1709 ECK1717 b1719 thrS thrS 40.54 64.89 87.81 77.25 0.28 0.312 0.342 0.286 20.68 23.05 25.27 21.12 73.936 6.06 e threonyl-tRNA synthetase Cytoplasmic 1QF6 "52954; Anticodon-binding domain of Class II aaRS -!- 55174; Alpha-L RNA-binding motif -!- 55186; Threonyl-tRNA synthetase (ThrRS), second 'additional' domain -!- 55681; Class II aaRS and biotin synthetases" JW1710 ECK1718 b1721 arpB arpB_2 23.39 34.56 91.59 128.09 0.159 0.17 0.137 0.146 8.3 8.89 7.16 7.64 52.262 9.11 su "predicted protein, C-ter fragment (pseudogene)" Cytoplasmic JW1719 ECK1728 b1730 ydjO ydjO 26.7 26.26 33.56 102.13 0.234 0.478 0.476 0.388 7.18 14.66 14.6 11.92 30.698 6.89 o predicted protein Cytoplasmic JW1722 ECK1731 b1733 chbG chbG ydjC -!- celG 27.22 23.81 75.17 58.41 0.846 1.731 2.059 1.825 23.48 48.03 57.12 50.64 27.743 6.24 o conserved protein Cytoplasmic JW1723 ECK1732 b1734 chbF chbF celF -!- ydjD 33.01 38.6 95.67 93.64 1.494 1.325 1.032 1.16 75.41 66.86 52.08 58.53 50.459 6.39 e "cryptic phospho-beta-glucosidase, NAD(P)-binding" Cytoplasmic 51735; NAD(P)-binding Rossmann-fold domains JW1730 ECK1739 b1741 ydjQ ydjQ cho -!- sosD 50.61 55.14 94.01 109.88 0.316 0.427 0.531 0.425 10.66 14.4 17.9 14.34 33.716 8.97 e endonuclease of nucleotide excision repair Cytoplasmic JW1731 ECK1740 b1742 ydjR ydjR ves 25.8 27.14 55.37 77.79 0.716 1.285 1.698 1.655 15.44 27.71 36.6 35.68 21.557 8.71 o conserved protein Cytoplasmic JW1734 ECK1743 b1745 astB astB ydjT 7.4 15.22 21.21 21.49 0.905 0.932 0.838 0.732 44.57 45.87 41.28 36.04 49.246 6.21 e succinylarginine dihydrolase Cytoplasmic JW1736 ECK1745 b1747 astA astA ydjV 13.16 28.56 65.06 73.83 1.01 1.081 1.046 1.061 38.79 41.52 40.17 40.74 38.416 6.62 e arginine succinyltransferase Cytoplasmic 55729; Acyl-CoA N-acyltransferases (Nat) JW1737 ECK1746 b1748 astC astC argM -!- cstC -!- ydjW 23.91 32.16 63.14 80.28 0.344 0.355 0.396 0.407 15.02 15.5 17.25 17.76 43.621 6.39 e "succinylornithine transaminase, PLP-dependent" Cytoplasmic 53383; PLP-dependent transferases JW1738 ECK1747 b1749 xthA xthA xth 80.03 67.83 90.97 102.44 0.332 0.564 0.553 0.499 10.26 17.46 17.11 15.43 30.936 6.45 e exonuclease III Cytoplasmic 1AKO 56219; DNase I-like JW1750 ECK1759 b1761 gdhA gdhA 14.36 34.9 40.13 73.89 0.898 0.928 1.15 1.046 43.56 45.04 55.83 50.75 48.53 6.53 e "glutamate dehydrogenase, NADP-specific" Cytoplasmic "51735; NAD(P)-binding Rossmann-fold domains -!- 53223; Aminoacid dehydrogenase-like, N-terminal domain" JW1759 ECK1768 b1770 ydjF ydjF 3.29 15.76 14.39 49.31 2.373 2.54 2.203 1.917 67 71.71 62.19 54.13 28.233 7.8 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix JW1762 ECK1771 b1773 ydjI ydjI 16.91 55.94 71.29 79.88 0.785 0.984 0.823 0.915 24.15 30.27 25.33 28.17 30.771 5.58 pe predicted aldolase Cytoplasmic 51569; Aldolase JW1770 ECK1779 b1781 yeaE yeaE 16.92 18.63 91.18 88.32 0.49 0.663 0.643 0.44 15.17 20.54 19.89 13.61 30.952 6.52 pe predicted oxidoreductase Cytoplasmic 51430; NAD(P)-linked oxidoreductase JW1779 ECK1788 b1790 yeaM yeaM 10.88 19.22 38.93 55.05 1.005 1.217 1.029 0.909 30.69 37.17 31.41 27.75 30.535 9.22 pr predicted DNA-binding transcriptional regulator Cytoplasmic 51182; RmlC-like JW1788 ECK1797 b1799 yeaT yeaT 7.64 13.97 40.36 37.94 1.744 1.958 1.473 1.443 60.32 67.75 50.95 49.93 34.597 6.85 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW1789 ECK1798 b1800 yeaU yeaU ttuC 9.21 12.87 49.04 54.56 1.01 1.261 1.199 1.3 40.68 50.76 48.27 52.34 40.266 5.83 pe predicted dehydrogenase Cytoplasmic 53659; Isocitrate & isopropylmalate dehydrogenases JW1793 ECK1802 b1804 rnd rnd 27.72 56.67 68.24 65.99 0.533 0.619 0.65 0.778 22.74 26.41 27.72 33.21 42.68 5.7 e ribonuclease D Cytoplasmic 53098; Ribonuclease H-like JW1797 ECK1806 b1808 yoaA yoaA 2.7 5.39 15.57 78.18 1.511 1.684 1.162 1.121 106.22 118.42 81.72 78.84 70.303 7.29 d conserved protein with nucleoside triphosphate hydrolase domain Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW1802 ECK1811 b1813 yeaB yeaB 18.86 40.65 50.54 57.2 2.013 2.24 1.499 1.909 43.11 47.96 32.1 40.87 21.413 6.74 pe predicted NUDIX hydrolase Cytoplasmic 55811; Nudix JW1827 ECK1837 b1838 pphA pphA prpA -!- yebX 14.94 19.25 60.2 69.59 1.588 1.781 1.532 1.167 40.11 44.97 38.69 29.48 25.259 7.63 e serine/threonine-specific protein phosphatase 1 Cytoplasmic 56300; Metallo-dependent phosphatases JW1832 ECK1844 b1843 yobB yobB 6.78 18 69.01 72.27 0.658 0.649 0.606 0.56 16.03 15.81 14.76 13.64 24.377 8.92 d conserved protein Cytoplasmic 56317; Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase JW1833 ECK1845 b1844 exoX exoX yobC 18.29 30.95 100.16 78.4 0.912 1.111 0.915 0.88 22.89 27.91 22.98 22.09 25.112 8.04 e DNA exonuclease X Cytoplasmic 53098; Ribonuclease H-like JW1834 ECK1846 b1845 ptrB ptrB tlp 7.45 14.15 18.17 53.79 0.487 0.609 0.473 0.583 38.7 48.39 37.57 46.26 79.405 5.93 e protease II Cytoplasmic "50993; Prolyl oligopeptidase, N-terminal domain -!- 53474; alpha/beta-Hydrolases" JW1842 ECK1854 b1853 yebK yebK hexR 43.65 96.42 109.84 124.34 0.882 0.977 0.665 0.876 28.17 31.19 21.25 27.97 31.943 7.01 pr predicted DNA-binding transcriptional regulator Cytoplasmic 53697; SIS domain JW1847 ECK1859 b1858 znuC znuC yebM 44.34 68.51 80.14 109.64 1.525 1.501 1.542 1.341 42.47 41.8 42.95 37.34 27.854 9.96 t zinc transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW1852 ECK1864 b1863 ruvC ruvC 12.55 27.17 25.77 49.16 4.059 3.525 4.607 3.845 76.04 66.04 86.3 72.02 18.734 10.2 cp "component of RuvABC resolvasome, endonuclease" Cytoplasmic 53098; Ribonuclease H-like JW1857 ECK1869 b1868 yecE yecE 7.08 17.1 76.15 31.65 1.041 0.987 0.809 0.867 32.74 31.06 25.44 27.27 31.457 8.36 o conserved protein Cytoplasmic JW1860 ECK1872 b1871 yecP yecP 8.38 28.7 78.59 56.09 1.304 0.931 1.241 1.253 48.21 34.41 45.89 46.33 36.97 6.7 pe predicted methyltransferase Cytoplasmic 53335; S-adenosyl-L-methionine-dependent methyltransferases JW1863 ECK1875 b1874 cutC cutC 18.44 42.74 91.74 59.29 1.209 1.032 1.281 0.964 32.33 27.59 34.25 25.78 26.732 6.31 t copper homeostasis protein Cytoplasmic 51391; Thiamin phosphate synthase JW1865 ECK1877 b1876 argS argS lov 21.09 27.98 18.51 113.91 1.183 1.119 0.715 0.636 76.43 72.31 46.17 41.12 64.604 5.59 e arginyl-tRNA synthetase Cytoplasmic "47323; Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases -!- 52374; Nucleotidylyl transferase -!- 55190; Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain" JW1872 ECK1884 b1883 cheB cheB 19.35 26.97 81.21 20.1 1.387 1.672 2.279 8.313 51.92 62.58 85.31 311.18 37.435 8.68 r "fused chemotaxis regulator -!- protein-glutamate methylesterase, in two-component regulatory system with CheA" Cytoplasmic "52172; CheY-like -!- 52738; Methylesterase CheB, C-terminal domain" JW1873 ECK1885 b1884 cheR cheR cheX 10.88 23.25 76.01 50.91 1.834 1.562 1.394 1.597 60.2 51.29 45.76 52.42 32.828 9.8 r chemotaxis regulator Cytoplasmic "47757; Chemotaxis receptor methyltransferase CheR, N-terminal domain -!- 53335; S-adenosyl-L-methionine-dependent methyltransferases" JW1880 ECK1892 b1891 flhC flhC flaI 9.31 23.94 24.18 31.18 2.091 1.793 1.896 1.578 45.05 38.64 40.86 34 21.547 8.19 r DNA-binding transcriptional regulator with FlhD Cytoplasmic JW1898 ECK1912 b1913 uvrC uvrC 13.85 24.73 14.79 31.07 0.435 0.512 0.718 0.717 29.66 34.85 48.92 48.89 68.137 9.5 e "excinuclease UvrABC, endonuclease subunit" Cytoplasmic "46600; C-terminal, UvrC-binding domain of UvrB -!- 47781; RuvA domain 2-like" JW1906 ECK1920 b1921 fliZ fliZ yedH 13.77 27.03 60.26 60.35 1.293 1.171 1.146 1.066 28 25.35 24.82 23.08 21.648 9.46 pr predicted regulator of FliA activity Cytoplasmic "47823; lambda integrase-like, N-terminal domain" JW1916 ECK1930 b1931 yedK yedK yedG 24.36 40.39 125.23 79.83 0.675 0.681 0.72 0.804 16.84 16.99 17.97 20.06 24.948 6.01 o predicted protein Cytoplasmic JW1917 ECK1931 b1932 yedL yedL 13.26 17.7 51.24 50.13 2.649 2.245 2.038 1.988 47.35 40.14 36.43 35.54 17.878 7.33 pe predicted acyltransferase Cytoplasmic 55729; Acyl-CoA N-acyltransferases (Nat) JW1920 ECK1933 b1935 yedM yedM 9.36 18.63 40.1 113.59 5.402 4.791 4.981 6.516 72.26 64.09 66.63 87.16 13.377 5.98 o conserved protein Cytoplasmic JW1925 ECK1939 b1941 fliI fliI flaC -!- fla AIII 21.1 35.27 69.25 91.31 0.579 0.599 0.609 0.468 28.55 29.51 30.02 23.07 49.263 7.45 e flagellum-specific ATP synthase Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW1961 ECK1975 b1980 yeeL yeeL_1 21.33 35.76 71.15 102.49 0.852 0.925 0.89 0.872 22.74 24.7 23.76 23.29 26.7 8.65 su "predicted protein, N-ter fragment (pseudogene)" Cytoplasmic JW1966 ECK1982 b1987 cbl cbl 23.48 51.57 38.6 104.96 0.979 0.99 1.042 0.948 35.05 35.44 37.31 33.93 35.812 5.92 r DNA-binding transcriptional activator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW1985 ECK1996 b2003 yeeT yeeT 14.7 42.81 21.3 81.63 10.921 9.975 8.512 9.474 91.84 83.88 71.58 79.67 8.409 10.75 h CP4-44 prophage; predicted protein Cytoplasmic JW1989 ECK2001 b2007 yeeX yeeX 8.61 16.04 11.97 13.93 3.503 3.407 3.392 3.476 52.97 51.51 51.28 52.56 15.12 9.81 o conserved protein Cytoplasmic JW1993 ECK2005 b2011 sbcB sbcB xonA -!- cpeA 19.09 24.5 75.41 96.26 0.864 0.873 1.059 1.037 47.04 47.51 57.66 56.45 54.438 5.86 e exonuclease I Cytoplasmic 1FXX 53098; Ribonuclease H-like JW2005 ECK2018 b2023 hisH hisH 14.57 30.9 97.35 50.1 1.266 1.353 1.908 1.462 27.38 29.26 41.26 31.63 21.627 6.41 e "imidazole glycerol phosphate synthase, glutamine amidotransferase subunit" Cytoplasmic 52317; Class I glutamine amidotransferase-like JW2010 ECK2023 b2028 ugd ugd UDG8 -!- yefA -!- udg 15.72 30.92 54.99 77.12 0.779 0.843 1.02 0.74 33.98 36.78 44.47 32.26 43.609 6.96 e UDP-glucose 6-dehydrogenase Cytoplasmic "48179; 6-phosphogluconate dehydrogenase C-terminal domain-like -!- 51735; NAD(P)-binding Rossmann-fold domains -!- 52413; UDP-glucose dehydrogenase (UDPGDH), C-terminal (UDP-binding) domain" JW2019 ECK2028 b2034 wbbI wbbI yefG 11.75 27.7 68.65 84.2 0.505 0.45 0.519 0.43 19.04 16.95 19.56 16.23 37.716 6.56 o conserved protein Cytoplasmic JW2021 ECK2030 b2036 glf glf yefE 5.9 16.43 46.85 63.19 0.51 0.506 0.502 0.416 21.91 21.74 21.55 17.84 42.926 7.45 e "UDP-galactopyranose mutase, FAD/NAD(P)-binding" Cytoplasmic "51971; Nucleotide-binding domain -!- 54373; FAD-linked reductases, C-terminal domain" JW2026 ECK2035 b2041 rfbB rfbB som -!- rmlB 24.67 64.74 80.31 91.02 0.623 0.539 0.689 0.566 25.26 21.84 27.91 22.93 40.513 5.96 e "dTDP-glucose 4,6 dehydratase, NAD(P)-binding" Cytoplasmic 51735; NAD(P)-binding Rossmann-fold domains JW2029 ECK2038 b2044 wcaL wcaL yefL 21.61 35.76 91.54 87.42 0.428 0.456 0.48 0.44 19.38 20.66 21.75 19.94 45.325 9.64 pe predicted glycosyl transferase Cytoplasmic 53756; UDP-Glycosyltransferase/glycogen phosphorylase JW2030 ECK2039 b2045 wcaK wcaK 3.05 11.93 38.4 43.81 1.278 1.093 1.313 1.409 60.47 51.71 62.13 66.66 47.302 7.16 pe predicted pyruvyl transferase Cytoplasmic JW2035 ECK2044 b2050 wcaI wcaI yefD 9.63 21.99 56.12 67.95 0.38 0.386 0.493 0.447 17.07 17.3 22.11 20.04 44.874 8.98 pe predicted glycosyl transferase Cytoplasmic 53756; UDP-Glycosyltransferase/glycogen phosphorylase JW2038 ECK2047 b2053 gmd gmd yefA -!- yefN 6.34 17.54 41.65 83.39 1.437 1.404 1.724 1.652 60.35 58.98 72.39 69.41 42.002 6.26 e "GDP-D-mannose dehydratase, NAD(P)-binding" Cytoplasmic 1DB3 51735; NAD(P)-binding Rossmann-fold domains JW2039 ECK2048 b2054 wcaF wcaF 7.96 26.8 43.33 43.47 3.423 2.346 2.441 2.697 68.28 46.79 48.69 53.79 19.949 9.96 pe predicted acyl transferase Cytoplasmic 51161; Trimeric LpxA-like enzymes JW2040 ECK2049 b2055 wcaE wcaE 10.9 28 38.92 74.42 1.974 1.703 1.719 1.666 55.02 47.47 47.91 46.46 27.877 9.9 pe predicted glycosyl transferase Cytoplasmic 53448; Nucleotide-diphospho-sugar transferases JW2042 ECK2051 b2057 wcaC wcaC 13.99 32.02 62.34 67.34 1.122 1.031 1.257 1.126 50.76 46.63 56.86 50.94 45.231 8.87 pe predicted glycosyl transferase Cytoplasmic 53756; UDP-Glycosyltransferase/glycogen phosphorylase JW2046 ECK2055 b2061 wzb wzb 20.33 21.43 69.56 65.82 3.694 4.192 4.037 3.772 61.68 69.99 67.41 62.98 16.696 7.99 e protein-tyrosine phosphatase Cytoplasmic 52788; Phosphotyrosine protein phosphatases I JW2053 ECK2062 b2068 alkA alkA aidA 30.41 22.87 82.12 61.97 1.261 1.341 1.442 1.317 39.56 42.04 45.23 41.31 31.363 8.45 e 3-methyl-adenine DNA glycosylase II Cytoplasmic 48150; DNA-glycosylase -!- 55945; TATA-box binding protein-like JW2054 ECK2063 b2069 yegD yegD 8.98 21.8 81.74 94.01 0.72 0.695 0.962 0.772 35.52 34.26 47.44 38.08 49.308 5.54 pf predicted chaperone Cytoplasmic 53067; Actin-like ATPase domain JW2081 ECK2087 b2094 gatA gatA 15.1 54.32 62.95 50.02 2.457 2.411 2.616 2.479 28.52 27.98 30.35 28.77 11.605 7.45 t galactitol-specific enzyme IIA component of PTS Cytoplasmic JW2082 ECK2088 b2095 gatZ gatZ 6.36 14.4 17.89 69.07 0.721 0.79 1.042 0.865 33.91 37.18 49.05 40.7 47.055 5.92 e "D-tagatose 1,6-bisphosphate aldolase 2, subunit" Cytoplasmic JW2088 ECK2094 b2101 yegW yegW 16.52 18.8 20.79 23.64 1.617 1.756 1.99 1.822 45.69 49.6 56.22 51.47 28.249 7.01 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix JW2090 ECK2096 b2103 thiD thiD thiA -!- thiJ -!- thiN 9.62 12.32 55.19 20.06 2.436 2.466 3.209 2.4 69.68 70.54 91.79 68.63 28.603 6.44 e bifunctional hydroxy-methylpyrimidine kinase -!- hydroxy-phosphomethylpyrimidine kinase Cytoplasmic 53613; Ribokinase-like JW2105 ECK2109 b2118 yehI yehI 1.11 2.99 13.2 66.11 0.024 0.038 0.03 0.027 3.34 5.29 4.09 3.66 137.926 6.44 o conserved protein Cytoplasmic JW2108 ECK2112 b2120 yehM yehM yehN -!- yehO 14.68 64.23 72.13 101.42 0.039 0.048 0.056 0.073 3.26 3.99 4.69 6.08 83.299 5.82 o predicted protein Cytoplasmic JW2110 ECK2114 b2122 yehQ yehQ 13.38 34.29 46.32 141.31 0.419 0.37 0.387 0.488 28.35 25 26.17 32.99 67.657 6.24 d predicted protein Cytoplasmic JW2117 ECK2122 b2129 yehX yehX 3.87 6.9 32.36 12.93 0.98 1.096 1.104 0.927 33.69 37.68 37.98 31.87 34.388 6.49 pt predicted transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases -!- 54631; CBS-domain JW2128 ECK2133 b2140 dusC dusC yohI 12.92 22.56 126.25 70.68 0.478 0.55 0.48 0.475 16.82 19.34 16.89 16.69 35.162 6.93 e tRNA-dihydrouridine synthase C Cytoplasmic 51395; FMN-linked oxidoreductases JW2133 ECK2139 b2146 yeiT yeiT 22.24 39.18 35.56 69.99 0.957 1.224 1.464 1.232 42.35 54.21 64.82 54.56 44.275 5.81 pe predicted oxidoreductase Cytoplasmic 46548; alpha-helical ferredoxin JW2136 ECK2142 b2149 mglA mglA mglP -!- PMG -!- mgl 22.78 29.68 69.73 84.12 0.299 0.392 0.441 0.483 16.85 22.12 24.85 27.2 56.362 8.03 t fused methyl-galactoside transporter subunitsl -!- ATP-binding components of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases -!- 52540; P-loop containing nucleotide triphosphate hydrolases JW2138 ECK2144 b2151 galS galS mglD 15.04 32.4 73.28 68.08 0.867 0.699 0.807 0.819 32.35 26.07 30.12 30.56 37.32 6.84 r DNA-binding transcriptional repressor Cytoplasmic 47413; lambda repressor-like DNA-binding domains -!- 53822; Periplasmic binding protein-like I JW2144 ECK2150 b2157 yeiE yeiE 11.76 30.9 44.51 49.45 1.156 1.014 1.167 1.026 37.78 33.16 38.15 33.53 32.691 6.67 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW2147 ECK2153 b2160 yeiI yeiI 19.67 36.83 64.17 75.95 0.524 0.518 0.749 0.687 20.8 20.56 29.72 27.25 39.666 6.03 pe predicted kinase Cytoplasmic 46785; Winged helix -!- 53613; Ribokinase-like JW2150 ECK2156 b2163 yeiL yeiL 12.51 30.16 66.12 102.41 1.255 0.891 0.952 0.83 31.71 22.52 24.07 20.98 25.275 8.3 r DNA-binding transcriptional activator Cytoplasmic 51206; cAMP-binding domain-like JW2153 ECK2159 b2166 yeiC yeiC 43.52 58.18 92.05 88.37 1.175 1.182 1.442 1.387 39.39 39.63 48.35 46.51 33.527 5.29 pe predicted kinase Cytoplasmic 53613; Ribokinase-like JW2172 ECK2178 b2184 yejH yejH yejI -!- yejJ 44.98 58.2 80.51 109.4 0.596 0.634 0.563 0.531 39.53 42.08 37.38 35.22 66.36 7.71 pe predicted ATP-dependet helicase Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW2196 ECK2200 b2208 napF napF yojG 11.79 29.13 107.23 20.65 1.248 1.069 1.385 1.445 22.5 19.28 24.97 26.06 18.034 7.68 c "ferredoxin-type protein, predicted role in electron transfer to periplasmic nitrate reductase (NapA)" Cytoplasmic 54862; 4Fe-4S ferredoxins JW2200 ECK2204 b2212 alkB alkB aidD 34.61 37.29 91.32 100.65 0.732 0.709 0.707 0.74 17.6 17.07 17.01 17.81 24.056 8.19 e oxidative demethylase of N1-methyladenine or N3-methylcytosine DNA lesions Cytoplasmic JW2216 ECK2215 b2222 atoA atoA 21.62 51.04 107.03 89.7 1.049 0.913 0.979 0.997 24.05 20.94 22.44 22.86 22.934 6.51 c "acetyl-CoA:acetoacetyl-CoA transferase, beta subunit" Cytoplasmic 53316; Glutaconate-CoA transferase subunits JW2218 ECK2217 b2224 atoB atoB 8.45 20.11 73.24 97.22 0.758 0.681 0.977 0.847 30.55 27.47 39.4 34.15 40.311 7.56 c acetyl-CoA acetyltransferase Cytoplasmic 53901; Thiolase-like JW2231 ECK2229 b2237 inaA inaA yfaG 11.53 25.03 41.11 43.07 0.687 0.507 0.551 0.548 17.37 12.81 13.94 13.84 25.282 9.61 d conserved protein Cytoplasmic 56112; Protein kinase-like (PK-like) JW2235 ECK2233 b2241 glpA glpA 4.01 10.49 47.01 74.89 1.149 1.026 1.009 0.893 67.67 60.43 59.41 52.62 58.899 6.61 e "sn-glycerol-3-phosphate dehydrogenase (anaerobic), large subunit, FAD/NAD(P)-binding" Cytoplasmic "51905; FAD/NAD(P)-binding domain -!- 54373; FAD-linked reductases, C-terminal domain" JW2237 ECK2235 b2243 glpC glpC 21.96 61.27 82.46 101.1 0.45 0.42 0.559 0.605 19.83 18.52 24.66 26.65 44.075 8.34 e "sn-glycerol-3-phosphate dehydrogenase (anaerobic), small subunit" Cytoplasmic 46548; alpha-helical ferredoxin JW2239 ECK2238 b2245 yfaU yfaU 37.11 55.02 67.44 84.7 1.461 1.192 1.243 0.986 42.2 34.44 35.9 28.49 28.881 6.36 pe "predicted 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase" Cytoplasmic 51621; Phosphoenolpyruvate/pyruvate domain JW2241 ECK2240 b2247 yfaW yfaW 10.03 31.47 68.75 80.34 0.725 0.729 0.797 0.747 32.39 32.56 35.62 33.36 44.667 6.19 pe predicted enolase Cytoplasmic 51604; Enolase C-terminal domain-like -!- 54826; Enolase N-terminal domain-like JW2249 ECK2248 b2255 yfbG yfbG arnA -!- pmrI -!- SAF 6.49 17.84 65.44 114.24 0.176 0.223 0.192 0.18 13.07 16.52 14.25 13.37 74.223 6.68 e fused UDP-L-Ara4N formyltransferase -!- UDP-GlcA C-4'-decarboxylase Cytoplasmic 50486; FMT C-terminal domain-like -!- 53328; Formyltransferase -!- 51735; NAD(P)-binding Rossmann-fold domains JW2250 ECK2249 b2256 yfbH yfbH 12.31 25.23 66.7 43.49 0.661 0.548 0.676 0.54 21.88 18.13 22.35 17.86 33.085 7.86 o conserved protein Cytoplasmic JW2263 ECK2262 b2268 elaC elaC ecoZ -!- rnz -!- zipD 21.43 41.3 71 77.48 0.877 0.696 0.827 0.722 28.86 22.89 27.21 23.74 32.895 6.25 e binuclear zinc phosphodiesterase Cytoplasmic 56281; Metallo-hydrolase/oxidoreductase JW2278 ECK2277 b2283 nuoG nuoG 6.22 19.46 26.64 64.71 0.323 0.415 0.568 0.617 32.43 41.64 57.07 61.97 100.438 6.09 c "NADH:ubiquinone oxidoreductase, chain G" Cytoplasmic "50692; ADC-like -!- 53706; Formate dehydrogenase/DMSO reductase, domains 1-3 -!- 54292; 2Fe-2S ferredoxin-like -!- 54862; 4Fe-4S ferredoxins" JW2279 ECK2278 b2284 nuoF nuoF ygfQ -!- nuoB 10.47 20.43 60.76 67.97 0.797 0.655 1.126 0.856 39.23 32.27 55.46 42.14 49.241 7.16 c "NADH:ubiquinone oxidoreductase, chain F" Cytoplasmic JW2284 ECK2283 b2289 lrhA lrhA genR 10.81 23.76 83.69 65.31 1.493 1.434 1.695 1.76 51.57 49.55 58.57 60.82 34.551 6.02 r DNA-binding transcriptional repressor Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW2287 ECK2284 b2290 yfbQ yfbQ 11.9 23.24 58.93 72.21 0.667 0.758 0.958 0.795 30.34 34.48 43.55 36.14 45.468 6.4 pe predicted aminotransferase Cytoplasmic 53383; PLP-dependent transferases JW2296 ECK2293 b2299 yfcD yfcD 84.84 100.16 100.98 93.58 0.875 0.778 0.7 0.735 17.8 15.83 14.24 14.96 20.342 4.96 pe predicted NUDIX hydrolase Cytoplasmic 55811; Nudix JW2301 ECK2298 b2304 yfcH yfcH 18.24 14.36 69.7 71.73 0.712 0.828 0.9 0.639 23.24 27.06 29.41 20.89 32.669 7.65 pe conserved protein with NAD(P)-binding Rossmann-fold domain Cytoplasmic 51735; NAD(P)-binding Rossmann-fold domains JW2308 ECK2305 b2311 ubiX ubiX dedF 15.04 32.21 44.49 49.18 1.441 1.196 1.223 1.046 29.78 24.73 25.29 21.62 20.675 7.38 e 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Cytoplasmic 52507; DFP DNA/pantothenate metabolism flavoprotein JW2309 ECK2306 b2312 purF purF adeub -!- purC -!- ade(ub) 31.77 49.51 75.45 83.81 0.582 0.719 0.861 0.777 32.81 40.56 48.59 43.85 56.42 5.73 e amidophosphoribosyltransferase Cytoplasmic 1ECG 53271; PRTase-like -!- 56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases) JW2317 ECK2314 b2320 pdxB pdxB 25.87 43.67 83.45 109.23 0.495 0.571 0.627 0.599 20.46 23.58 25.9 24.75 41.326 6.83 e erythronate-4-phosphate dehydrogenase Cytoplasmic 51735; NAD(P)-binding Rossmann-fold domains -!- 52283; Formate/glycerate dehydrogenase catalytic domain-like JW2320 ECK2317 b2323 fabB fabB fabC 14.67 26.16 75.24 93.59 1.92 1.171 1.909 2.02 81.7 49.84 81.27 85.98 42.563 5.89 e 3-oxoacyl-[acyl-carrier-protein] synthase I Cytoplasmic 1OG9 53901; Thiolase-like JW2338 ECK2335 b2341 yfcX yfcX fadJ 8.4 16.83 35.26 54.42 0.67 0.675 0.853 0.679 51.6 52.01 65.7 52.29 77.006 9.14 e "fused enoyl-CoA hydratase-!-epimerase-!-isomerase -!- 3-hydroxyacyl-CoA dehydrogenase, subunit of anaerobic fatty acid oxidation complex" Cytoplasmic 52096; ClpP/crotonase -!- 48179; 6-phosphogluconate dehydrogenase C-terminal domain-like -!- 51735; NAD(P)-binding Rossmann-fold domains -!- 52096; ClpP/crotonase JW2339 ECK2336 b2342 yfcY yfcY fadI 5.39 14.58 86.91 43.87 0.751 0.835 0.983 1.072 34.89 38.82 45.7 49.82 46.488 8.97 e "beta-ketoacyl-CoA thiolase, anaerobic, subunit" Cytoplasmic 53901; Thiolase-like JW2358 ECK2355 b2361 yfdR yfdR 7.16 16.23 68.67 23.71 2.927 2.226 2.956 2.246 59.21 45.03 59.8 45.45 20.232 6.35 h CPS-53 (KpLE1) prophage; conserved protein Cytoplasmic JW2361 ECK2360 b2364 dsdC dsdC 12.02 26.6 52.71 36.89 1.344 1.212 1.238 1.262 47.45 42.8 43.71 44.57 35.304 7.14 r DNA-binding transcriptional dual regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW2370 ECK2369 b2373 oxc oxc yfdU 25.36 43.83 61.85 90.9 0.96 0.979 0.991 1.131 58.09 59.27 59.97 68.45 60.513 6.13 pe predicted oxalyl-CoA decarboxylase Cytoplasmic 52467; DHS-like NAD/FAD-binding domain -!- 52518; Thiamin diphosphate-binding fold (THDP-binding) JW2379 ECK2378 b2382 ypdC ypdC 14.88 31.6 46.71 56.8 0.635 0.549 0.659 0.466 20.53 17.75 21.3 15.07 32.333 9.76 pr predicted DNA-binding protein Cytoplasmic 46689; Homeodomain-like JW2393 ECK2392 b2398 yfeC yfeC 7.77 10.61 9.76 14.36 5.541 5.163 5.165 5.104 70.42 65.61 65.65 64.86 12.709 10.21 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix JW2394 ECK2393 b2399 yfeD yfeD 12.56 13.16 94 15.51 4.205 3.943 3.653 3.381 62.63 58.73 54.41 50.36 14.895 8.61 pr predicted DNA-binding transcriptional regulator Cytoplasmic 47413; lambda repressor-like DNA-binding domains JW2398 ECK2401 b2407 xapA xapA pndA 26.35 37.07 89.02 77.93 0.305 0.264 0.344 0.235 9.1 7.85 10.26 7.01 29.804 6.76 e purine nucleoside phosphorylase II Cytoplasmic 53167; Purine and uridine phosphorylases JW2400 ECK2403 b2409 yfeR yfeR 10.97 21.38 42.24 37.04 1.225 1.182 1.557 1.576 41.49 40.03 52.72 53.38 33.869 7.35 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW2411 ECK2413 b2418 pdxK pdxK pdxL -!- thiJ -!- yfeI 65.51 65.98 86.85 89.95 1.311 1.338 1.424 1.143 40.39 41.21 43.86 35.21 30.809 6.01 e pyridoxal-pyridoxamine kinase/hydroxymethylpyrimidine kinase Cytoplasmic 53613; Ribokinase-like JW2413 ECK2415 b2420 yfeS yfeS 18.98 28.13 66.23 101.87 1.158 1.086 1.298 0.936 32.65 30.64 36.6 26.4 28.205 5.55 o conserved protein Cytoplasmic JW2415 ECK2417 b2422 cysA cysA 5.56 10.84 38.6 32.73 2.675 2.278 2.764 2.158 109.76 93.45 113.39 88.55 41.025 8.23 t sulfate/thiosulfate transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW2420 ECK2422 b2427 yfeT yfeT 36.93 46.64 67.2 76.91 1.327 1.236 1.526 1.227 41.34 38.52 47.55 38.24 31.164 9.3 pr predicted DNA-binding transcriptional regulator Cytoplasmic 53697; SIS domain JW2424 ECK2426 b2431 yfeX yfeX 62.27 89.85 74.6 85.57 1.822 1.803 1.82 1.715 60.15 59.52 60.09 56.62 33.013 5.89 d conserved protein Cytoplasmic JW2430 ECK2432 b2437 yfeG yfeG eutR 9.38 21.85 59.48 50.59 1.08 1.178 1.251 1.334 43.32 47.25 50.19 53.52 40.125 6.82 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46689; Homeodomain-like JW2432 ECK2434 b2439 eutL eutL yffJ 18.46 33.04 85.44 80.83 1.064 1.013 1.312 1.003 24.22 23.05 29.87 22.82 22.757 5.75 ps predicted carboxysome structural protein with predicted role in ethanolamine utilization Cytoplasmic JW2433 ECK2435 b2440 eutC eutC 62.84 77.26 84.66 88.79 0.869 0.849 1.039 0.978 27.59 26.94 32.98 31.04 31.747 7.39 e "ethanolamine ammonia-lyase, small subunit (light chain)" Cytoplasmic JW2434 ECK2436 b2441 eutB eutB 11.12 20.4 58.12 61.96 1.494 1.3 1.657 1.633 73.69 64.15 81.76 80.56 49.334 4.95 e "ethanolamine ammonia-lyase, large subunit, heavy chain" Cytoplasmic JW2437 ECK2448 b2453 eutG eutG yffV 4.82 11.65 48.01 53.12 1.151 1.291 1.391 0.87 47.17 52.93 57 35.67 40.989 6.53 pe predicted alcohol dehydrogenase in ethanolamine utilization Cytoplasmic 56796; Dehydroquinate synthase-like JW2448 ECK2459 b2464 talA talA 18.72 29.76 76.99 80.12 0.789 0.812 0.68 0.659 28.12 28.91 24.21 23.47 35.62 6.57 e transaldolase A Cytoplasmic 51569; Aldolase JW2449 ECK2460 b2465 tktB tktB 14.21 32.92 19.93 68.69 0.51 0.607 0.663 0.736 37.23 44.27 48.39 53.69 72.969 6.13 e "transketolase 2, thiamin-binding" Cytoplasmic 52518; Thiamin diphosphate-binding fold (THDP-binding) -!- 52922; Transketolase C-terminal domain-like JW2452 ECK2463 b2468 aegA aegA yffG 33.85 41.94 41.78 74.32 0.588 0.819 0.801 0.838 42.18 58.78 57.53 60.19 71.78 6.58 pe fused predicted FeS binding subunit -!- predicted NAD/FAD-binding subunit of oxidoreductase Cytoplasmic 54862; 4Fe-4S ferredoxins -!- 51905; FAD/NAD(P)-binding domain -!- 51971; Nucleotide-binding domain -!- 54862; 4Fe-4S ferredoxins JW2456 ECK2467 b2472 dapE dapE dapB -!- msgB 16.3 26.62 50.88 68.56 1.035 0.916 1.121 1.192 42.65 37.76 46.22 49.15 41.22 5.85 e N-succinyl-diaminopimelate deacylase Cytoplasmic "53187; Zn-dependent exopeptidases -!- 55031; Carboxypeptidase G2, dimerisation domain" JW2459 ECK2470 b2474 ypfI ypfI 7.1 9.5 50.39 69.42 0.406 0.402 0.45 0.497 30.38 30.07 33.65 37.17 74.827 7.67 pe predicted hydrolase Cytoplasmic 52540; P-loop containing nucleoside triphosphate hydrolases -!- 55729; Acyl-CoA N-acyltransferases (Nat) JW2473 ECK2484 b2488 hyfH hyfH 10.94 24.25 56.96 39.28 2.092 1.585 1.87 1.684 42.13 31.93 37.66 33.92 20.141 8.01 c "hydrogenase 4, Fe-S subunit" Cytoplasmic 54862; 4Fe-4S ferredoxins JW2476 ECK2487 b2491 hyfR hyfR 11.78 8.77 27.46 58 0.255 0.538 0.397 0.463 19.21 40.46 29.86 34.83 75.227 6.13 r "DNA-binding transcriptional activator, formate sensing" Cytoplasmic 48283; FIS-like -!- 52540; P-loop containing nucleotide triphosphate hydrolases -!- 55781; GAF domain JW2486 ECK2497 b2501 ppk ppk 7.17 14.73 60.17 61.88 0.273 0.264 0.251 0.308 21.94 21.2 20.18 24.77 80.363 9.47 e "polyphosphate kinase, component of RNA degradosome" Cytoplasmic 56024; Phospholipase D/nuclease JW2521 ECK2534 b2537 hcaR hcaR yfhT -!- phdR 7.12 12.72 43.99 38.36 2.161 2.181 2.63 2.183 70.9 71.54 86.26 71.6 32.802 6.96 r DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW2522 ECK2535 b2538 hcaE hcaE hcaA1 -!- digA -!- hcaA -!- hcaa1 -!- phdC1 -!- yfhU 13.15 22.77 60.73 75.55 0.673 0.752 0.704 0.591 34.37 38.39 35.92 30.15 51.048 5.72 e "3-phenylpropionate dioxygenase, large (alpha) subunit" Cytoplasmic 50022; ISP domain -!- 55961; Bet v1-like JW2523 ECK2536 b2539 hcaF hcaF hcaA2 -!- digB -!- hcaa2 -!- phdC2 -!- hcaA -!- hcaB -!- yfhV 6.84 10.65 20.83 46.74 1.857 2.163 2.249 2.137 38.17 44.48 46.24 43.93 20.559 7.43 e "3-phenylpropionate dioxygenase, small (beta) subunit" Cytoplasmic 54427; NTF2-like JW2525 ECK2538 b2541 hcaB hcaB dig -!- phd -!- hcaa2 -!- phdD -!- yfhX 5.62 14.72 67.84 27.2 0.789 0.88 0.911 0.809 22.47 25.05 25.93 23.03 28.469 6.71 e "2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase" Cytoplasmic 51735; NAD(P)-binding Rossmann-fold domains JW2531 ECK2544 b2547 yphE yphE 8.86 22.21 18.32 93.71 0.988 0.98 1.113 1.029 54.3 53.86 61.17 56.52 54.951 6 pt fused predicted sugar transporter subunits -!- ATP-binding components of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases -!- 52540; P-loop containing nucleotide triphosphate hydrolases JW2543 ECK2557 b2559 tadA tadA yfhC 8.97 21.36 33.98 31.01 3.546 2.737 3.942 3.275 70.96 54.79 78.89 65.54 20.014 8.74 e tRNA-specific adenosine deaminase Cytoplasmic 53927; Cytidine deaminase JW2558 ECK2572 b2574 nadB nadB nic -!- nicB 29.32 43.73 81.63 97.49 0.294 0.369 0.369 0.356 17.73 22.24 22.23 21.49 60.279 6.17 e "quinolinate synthase, L-aspartate oxidase (B protein) subunit" Cytoplasmic 1CHU 46977; Succinate dehydrogenase/fumarate reductase C-terminal domain -!- 51905; FAD/NAD(P)-binding domain -!- 56425; Succinate dehydrogenase/fumarate reductase catalytic domain JW2561 ECK2575 b2577 yfiE yfiE 5.38 14.96 28.78 56.72 1.475 1.531 1.41 1.186 48.99 50.85 46.81 39.39 33.209 7.12 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW2564 ECK2578 b2580 ung ung 12.32 22.22 67.1 53.09 1.313 1.367 1.312 1.189 33.72 35.11 33.69 30.53 25.675 7.55 e uracil-DNA-glycosylase Cytoplasmic 1LQM 52141; DNA glycosylase JW2568 ECK2582 b2584 yfiQ yfiQ 4.94 9.98 21.18 91.93 0.238 0.379 0.317 0.279 23.3 37.11 31.03 27.35 97.884 6.26 pe fused predicted acyl-CoA synthetase NAD(P)-binding subunit -!- ATP-binding subunit Cytoplasmic 51735; NAD(P)-binding Rossmann-fold domains -!- 52210; Succinyl-CoA synthetase domains -!- 55729; Acyl-CoA N-acyltransferases (Nat) -!- 56059; Glutathione synthetase ATP-binding domain-like JW2570 ECK2584 b2586 yfiM yfiM 13.34 26.96 18.09 128.98 4.603 3.997 4.781 4.7 45.66 39.66 47.43 46.63 9.921 7.48 o predicted protein Cytoplasmic JW2575 ECK2591 b2593 yfiH yfiH 30.01 19.19 83.65 33.57 1.527 1.326 1.332 1.55 40.17 34.89 35.04 40.78 26.312 7.14 o conserved protein Cytoplasmic 1U05 JW2602 ECK2618 b2622 intA intA slpA -!- intX 4.37 11.63 11.44 60.72 0.976 1.258 1.126 1.169 45.48 58.66 52.47 54.51 46.619 10.17 h CP4-57 prophage; integrase Cytoplasmic 56349; DNA breaking-rejoining enzymes JW2603 ECK2619 b2623 yfjH yfjH 20.15 28.6 37.5 86.86 0.298 0.404 0.346 0.361 11.06 15 12.86 13.38 37.104 7.71 h CP4-57 prophage; predicted protein Cytoplasmic JW2609 ECK2624 b2628 yfjL yfjL 11.82 36.6 35.1 113.72 0.328 0.283 0.274 0.129 20.34 17.52 16.95 7.97 61.937 5.9 h CP4-57 prophage; predicted protein Cytoplasmic JW2611 ECK2626 b2630 yfjN yfjN std 4.31 11.03 28.81 40.43 1.185 1.717 1.681 1.324 47.41 68.7 67.27 52.98 40.022 7.08 h CP4-57 prophage; predicted protein Cytoplasmic JW2614 ECK2629 b2633 yfjQ yfjQ 8.56 14.12 49.51 33.16 0.995 0.979 1.313 1.218 31.08 30.59 41.01 38.03 31.233 10.06 h CP4-57 prophage; predicted protein Cytoplasmic JW2631 ECK2650 b4462 ygaR ygaR 15.7 28.07 53.67 85.36 1.519 1.419 1.893 1.478 39.09 36.52 48.74 38.06 25.743 6.02 o predicted protein Cytoplasmic JW2635 ECK2654 b2660 ygaF ygaF 8.89 18.86 90.04 58.42 0.735 1.026 0.966 0.721 33.83 47.23 44.46 33.21 46.045 8.41 pe predicted enzyme Cytoplasmic JW2639 ECK2658 b2664 csiR csiR gabC -!- ygaE 7.64 12.62 34.42 14.56 2.636 2.808 2.884 3.086 65.8 70.11 72 77.04 24.966 7.03 r DNA-binding transcriptional dual regulator Cytoplasmic 46785; Winged helix JW2644 ECK2663 b2669 stpA stpA hnsB -!- rsv 20.21 34.06 19.48 19.59 2.881 2.749 3.55 3.378 44.17 42.14 54.42 51.79 15.331 9.53 r "DNA binding protein, nucleoid-associated" Cytoplasmic 47729; IHF-like DNA-binding proteins JW2650 ECK2669 b2675 nrdE nrdE 4.51 5.57 19.12 78.14 1.103 1.383 0.636 0.748 88.66 111.19 51.14 60.15 80.397 6.44 e "ribonucleoside-diphosphate reductase 2, alpha subunit" Cytoplasmic "48168; R1 subunit of ribonucleotide reductase, N-terminal domain -!- 51998; PFL-like glycyl radical enzymes" JW2663 ECK2683 b2688 gshA gshA gsh-I -!- gshI 27.86 70.42 68.21 99.74 0.326 0.274 0.332 0.231 18.99 15.97 19.34 13.46 58.197 5.64 e gamma-glutamate-cysteine ligase Cytoplasmic JW2665 ECK2685 b2690 yqaB yqaB 16.62 32.22 68.75 44.02 2.022 1.62 2.229 1.533 41.96 33.62 46.26 31.81 20.757 6.23 pe predicted hydrolase Cytoplasmic 56784; HAD-like JW2686 ECK2711 b2716 ascB ascB sac 28.34 42.35 54.34 82.36 0.522 0.846 0.815 0.641 28.15 45.6 43.91 34.52 53.873 5.96 e cryptic 6-phospho-beta-glucosidase Cytoplasmic 51445; (Trans)glycosidases JW2691 ECK2716 b2721 hycE hycE hevE 13.49 38.01 121.33 105.3 0.336 0.402 0.394 0.362 21.78 26.08 25.6 23.5 64.914 6.55 e "hydrogenase 3, large subunit" Cytoplasmic "56762; Nickel-iron hydrogenase, large subunit" JW2699 ECK2724 b2729 hypD hypD hydF 20.61 24.5 69.15 70.33 0.614 0.955 1.049 0.994 25.35 39.47 43.36 41.09 41.32 6.28 f protein required for maturation of hydrogenases Cytoplasmic JW2700 ECK2725 b2730 hypE hypE hydB 27.97 88.36 104.94 84.8 0.496 0.557 0.632 0.628 16.71 18.76 21.27 21.14 33.668 5.57 e "carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein" Cytoplasmic 55326; Aminoimidazole ribonucleotide synthetase (PurM) N-terminal domain JW2701 ECK2726 b2731 fhlA fhlA fhl 3.26 6.42 19.93 75.93 0.349 0.318 0.344 0.303 27.33 24.91 26.92 23.72 78.374 5.68 r DNA-binding transcriptional activator Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases -!- 55781; GAF domain JW2704 ECK2729 b2734 pphB pphB prpB -!- ygbH 38.03 92.62 102.47 78.73 0.304 0.329 0.377 0.384 7.62 8.24 9.45 9.62 25.068 5.83 e serine/threonine-specific protein phosphatase 2 Cytoplasmic 56300; Metallo-dependent phosphatases JW2705 ECK2730 b2735 ygbI ygbI 13.5 23.02 26.18 124.09 0.948 0.885 1.55 1.214 27.06 25.26 44.23 34.64 28.534 7.84 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix JW2707 ECK2732 b2737 ygbK ygbK 27.36 33.57 88.16 101.02 0.394 0.507 0.559 0.575 16.26 20.92 23.1 23.76 41.295 6.59 o conserved protein Cytoplasmic JW2709 ECK2734 b2739 ygbM ygbM 12.57 20.64 85.64 72.54 0.35 0.392 0.411 0.338 10.22 11.45 12 9.85 29.18 5.67 d conserved protein Cytoplasmic 1K77 51658; Xylose isomerase-like JW2713 ECK2738 b2743 pcm pcm 19.82 19.77 80.9 52.46 0.928 1.204 1.353 1.068 21.55 27.97 31.43 24.83 23.235 7.96 e L-isoaspartate protein carboxylmethyltransferase type II Cytoplasmic 53335; S-adenosyl-L-methionine-dependent methyltransferases JW2722 ECK2747 b2752 cysD cysD 10.28 13.39 82.51 28.84 0.925 0.822 1.454 1.176 32.52 28.89 51.11 41.33 35.158 8.54 e "sulfate adenylyltransferase, subunit 2" Cytoplasmic 52402; Adenine nucleotide alpha hydrolases JW2726 ECK2751 b2756 ygcH ygcH 17.5 48.89 58.85 68.26 0.953 0.821 1.135 0.841 21.22 18.29 25.3 18.74 22.281 10.14 o predicted protein Cytoplasmic JW2728 ECK2753 b2758 ygcJ ygcJ 19.25 25.49 55.04 85.09 0.78 0.96 1.086 0.939 31.18 38.38 43.44 37.56 39.983 6.61 o predicted protein Cytoplasmic JW2730 ECK2755 b2760 ygcL ygcL ygcL 15.48 33.58 83.89 93.24 0.189 0.174 0.199 0.195 10.58 9.71 11.1 10.91 55.856 8.25 o predicted protein Cytoplasmic JW2732 ECK2757 b2762 cysH cysH 15.38 47.99 89.22 46.74 0.995 1.132 1.477 1.297 27.81 31.63 41.28 36.24 27.943 6.31 e 3'-phosphoadenosine 5'-phosphosulfate reductase Cytoplasmic 1SUR 52402; Adenine nucleotide alpha hydrolases JW2734 ECK2759 b2764 cysJ cysJ cysP 22.09 45.05 27.41 55.82 0.739 0.577 0.644 0.746 48.88 38.18 42.63 49.34 66.179 4.94 e "sulfite reductase, alpha subunit, flavoprotein" Cytoplasmic "52218; Flavoproteins -!- 52343; Ferredoxin reductase-like, C-terminal NADP-linked domain -!- 63380; Riboflavin synthase domain-like" JW2736 ECK2761 b2766 ygcN ygcN 10.61 13.99 57.91 70.93 0.245 0.311 0.345 0.317 11.35 14.42 15.99 14.68 46.347 6.38 pe "predicted oxidoreductase, FAD/NAD(P)-binding domain" Cytoplasmic 51905; FAD/NAD(P)-binding domain JW2758 ECK2781 b2787 gudD gudD ygcX 7.95 25.75 78.34 72.81 0.342 0.323 0.376 0.315 16.8 15.87 18.44 15.45 49.088 6.12 e (D)-glucarate dehydratase 1 Cytoplasmic 1EC7 51604; Enolase C-terminal domain-like -!- 54826; Enolase N-terminal domain-like JW2759 ECK2782 b2788 gudX gudX ygcY 19.27 27.79 85.27 91.02 0.308 0.418 0.447 0.403 15.04 20.38 21.83 19.66 48.797 6.16 pe predicted glucarate dehydratase Cytoplasmic 51604; Enolase C-terminal domain-like -!- 54826; Enolase N-terminal domain-like JW2762 ECK2785 b2791 yqcB yqcB truC 16.17 33.21 75.03 48.46 1.969 1.595 2.358 2.104 58.38 47.28 69.89 62.37 29.644 7.26 e tRNA pseudouridine synthase Cytoplasmic 50044; SH3-domain JW2766 ECK2790 b2795 ygdH ygdH 7.6 19.98 74.33 55.95 0.788 0.845 0.813 0.844 40.1 43.03 41.37 42.99 50.918 6.55 o conserved protein Cytoplasmic JW2774 ECK2798 b2803 fucK fucK 5.92 22.67 57.25 65.82 0.702 0.515 0.743 0.747 37.32 27.4 39.5 39.72 53.173 5.93 e L-fuculokinase Cytoplasmic 53067; Actin-like ATPase domain JW2779 ECK2803 b2808 gcvA gcvA 5.07 17.99 38.06 23.46 0.917 0.716 0.69 0.851 31.51 24.62 23.73 29.25 34.376 9.54 r DNA-binding transcriptional dual regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW2781 ECK2806 b2810 csdA csdA ygdJ 7.44 13.04 35.63 55.82 0.698 0.644 0.744 0.586 30.13 27.81 32.14 25.32 43.183 5.88 e cysteine sulfinate desulfinase Cytoplasmic 53383; PLP-dependent transferases JW2787 ECK2815 b2819 recD recD hopE 16.91 26.92 73 74.01 0.8 0.664 0.682 0.68 53.46 44.39 45.59 45.46 66.84 6.97 e "exonuclease V (RecBCD complex), alpha chain" Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW2790 ECK2818 b2822 recC recC 24.43 59.35 43.34 91.05 0.047 0.04 0.055 0.076 6.01 5.13 7.07 9.72 128.67 4.75 e "exonuclease V (RecBCD complex), gamma chain" Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW2795 ECK2823 b2827 thyA thyA 10.77 22.96 49.55 45.77 0.553 0.474 0.676 0.53 16.84 14.44 20.59 16.13 30.447 6.21 e thymidylate synthetase Cytoplasmic 2KCE 55831; Thymidylate synthase/dCMP hydroxymethylase JW2797 ECK2825 b2829 ptsP ptsP ygdF -!- ygdO 25.65 40.32 54.7 101.51 0.234 0.357 0.32 0.266 19.61 29.86 26.74 22.24 83.617 5.88 t fused PEP-protein phosphotransferase (enzyme I) of PTS system Cytoplasmic "55781; GAF domain -!- 47831; Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain -!- 51621; Phosphoenolpyruvate/pyruvate domain -!- 52009; Histidine-containing phosphotransfer domain, HPT domain" JW2802 ECK2830 b2834 tas tas ygdS 7.94 21.56 69.16 30.95 1.245 1.147 1.451 1.258 47.9 44.11 55.82 48.37 38.463 6.89 pe "predicted oxidoreductase, NADP(H)-dependent aldo-keto reductase" Cytoplasmic 1LQA 51430; NAD(P)-linked oxidoreductase JW2807 ECK2837 b2839 lysR lysR 3.69 9.47 52.77 20.32 1.242 0.958 1.08 0.873 42.65 32.9 37.08 29.97 34.336 7.75 r DNA-binding transcriptional dual regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW2808 ECK2838 b2840 ygeA ygeA 12.35 17.25 55.19 35.88 2.075 1.613 2.131 2.164 52.31 40.66 53.74 54.56 25.215 5.82 pe predicted racemase Cytoplasmic 53681; Glutamate racemase JW2815 ECK2845 b2847 yqeI yqeI 16.47 7.37 35.59 38.57 2.463 2.77 3.314 3.188 75.94 85.4 102.16 98.3 30.832 9.03 pr predicted transcriptional regulator Cytoplasmic "46894; C-terminal, effector domain of the bipartite response regulators" JW2817 ECK2847 b2849 yqeK yqeK 9.53 16.25 12.64 44.68 2.936 2.857 3.539 3.398 47.74 46.44 57.54 55.24 16.259 9.48 o predicted protein Cytoplasmic JW2818 ECK2848 b2850 ygeF ygeF 14.66 37.58 65.66 81.35 1.501 1.318 1.598 1.226 25.32 22.22 26.95 20.68 16.866 9.63 o predicted protein Cytoplasmic JW2820 ECK2850 b2852 ygeH ygeH 11.69 29.86 45.72 75.38 0.211 0.138 0.216 0.18 11.13 7.25 11.41 9.48 52.7 6.62 pr predictedtranscriptional regulator Cytoplasmic "46894; C-terminal, effector domain of the bipartite response regulators -!- 48452; TPR-like" JW2835 ECK2863 b2867 xdhB xdhB ygeT 9.11 12.94 62.91 39.92 0.702 0.67 0.736 0.611 22.15 21.12 23.21 19.27 31.534 7.16 e "xanthine dehydrogenase, FAD-binding subunit" Cytoplasmic 55447; CO dehydrogenase flavoprotein C-terminal domain-like -!- 56176; FAD-binding domain JW2837 ECK2865 b2869 ygeV ygeV 13.07 24.45 38.34 73.1 0.575 0.474 0.602 0.741 37.94 31.28 39.75 48.91 66.029 6.44 pr predicted DNA-binding transcriptional regulator Cytoplasmic 48283; FIS-like -!- 52540; P-loop containing nucleotide triphosphate hydrolases -!- 55781; GAF domain -!- 55785; PYP-like sensor domain JW2841 ECK2869 b2873 hyuA hyuA ygeZ 8.22 13.3 50.04 45.57 0.433 0.266 0.406 0.418 22.07 13.56 20.67 21.3 50.977 6.58 e D-stereospecific phenylhydantoinase Cytoplasmic 51338; Composite domain of metallo-dependent hydrolases -!- 51556; Metallo-dependent hydrolases JW2843 ECK2871 b2875 yqeB yqeB 18.1 38.01 34.52 50.28 0.888 0.569 0.773 0.914 51.19 32.77 44.53 52.67 57.625 6.78 d conserved protein with NAD(P)-binding Rossman fold Cytoplasmic 51230; Single hybrid motif -!- 51735; NAD(P)-binding Rossmann-fold domains JW2845 ECK2873 b2877 ygfJ ygfJ 20.07 26.94 88.53 58.79 2.247 2.446 2.76 2.376 48.29 52.57 59.33 51.05 21.491 6.55 d conserved protein Cytoplasmic 53448; Nucleotide-diphospho-sugar transferases JW2847 ECK2875 b2879 ssnA ssnA ygfL 6.78 22.14 39.14 69.01 0.978 0.785 1.185 1.001 47.72 38.32 57.82 48.83 48.793 6.2 pe predicted chlorohydrolase/aminohydrolase Cytoplasmic 51338; Composite domain of metallo-dependent hydrolases JW2870 ECK2897 b2902 ygfF ygfF yqfD 14.37 22.9 49 64.64 1.419 1.102 1.284 1.439 36.77 28.54 33.26 37.29 25.909 6.85 pe predicted NAD(P)-binding oxidoreductase with NAD(P)-binding Rossmann-fold domain Cytoplasmic 51735; NAD(P)-binding Rossmann-fold domains JW2871 ECK2898 b2903 gcvP gcvP 29.4 61.78 61.39 109.15 0.194 0.195 0.174 0.181 20.19 20.36 18.18 18.91 104.262 5.83 e "glycine decarboxylase, PLP-dependent, subunit (protein P) of glycine cleavage complex" Cytoplasmic 53383; PLP-dependent transferases JW2875 ECK2902 b2907 ubiH ubiH visB -!- acd 21.97 30.32 48.1 43.9 1.271 0.902 1.334 1.183 53.69 38.11 56.38 49.98 42.256 7.33 e "2-octaprenyl-6-methoxyphenol hydroxylase, FAD/NAD(P)-binding" Cytoplasmic 51905; FAD/NAD(P)-binding domain JW2879 ECK2907 b2912 ygfA ygfA 10.62 13.79 44.21 15.89 0.876 0.826 0.988 0.871 18.47 17.42 20.83 18.37 21.085 7.44 pe predicted ligase Cytoplasmic JW2883 ECK2912 b2916 argP argP iciA 8.13 15.11 77.03 31.82 0.839 0.78 0.902 0.789 28.04 26.09 30.16 26.37 33.438 7.27 r "DNA-binding transcriptional activator, replication initiation inhibitor" Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW2884 ECK2913 b2917 yliK yliK sbm 21.76 58.37 45.58 96.79 0.366 0.289 0.332 0.372 28.43 22.44 25.83 28.95 77.771 5.14 e methylmalonyl-CoA mutase Cytoplasmic 51703; Cobalamin (vitamin B12)-dependent enzymes -!- 52242; Cobalamin (vitamin B12)-binding domain JW2885 ECK2914 b2918 argK argK ygfD 36.43 25.58 71.17 75.35 1.378 1.381 1.537 1.673 50.52 50.64 56.35 61.33 36.666 6.78 t membrane ATPase/protein kinase Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW2887 ECK2916 b2920 ygfH ygfH 6.42 16.38 48.45 49.33 1.077 1.049 1.13 1.03 57.92 56.39 60.75 55.41 53.773 6.41 e propionyl-CoA:succinate-CoA transferase Cytoplasmic 53316; Glutaconate-CoA transferase subunits JW2895 ECK2924 b2928 yggC yggC 22.53 27.64 69.89 87.26 1.329 1.248 1.481 1.376 36 33.83 40.14 37.29 27.101 6.13 d conserved protein with nucleoside triphosphate hydrolase domain Cytoplasmic 52540; P-loop containing nucleoside triphosphate hydrolases JW2913 ECK2941 b2946 yggJ yggJ 17.89 32.08 81.18 88.46 1.614 1.464 1.698 1.56 43.5 39.45 45.76 42.05 26.951 6.97 o predicted protein Cytoplasmic JW2917 ECK2945 b2950 yggR yggR 13.24 24.37 68.07 88.88 0.7 0.774 0.916 0.805 25.18 27.83 32.93 28.94 35.956 6.26 pt predicted transporter Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW2922 ECK2950 b2955 yggW yggW 21.36 26.44 87.49 78.46 1.361 1.417 1.685 1.788 57.89 60.29 71.66 76.05 42.535 5.91 pe predicted oxidoreductase Cytoplasmic JW2947 ECK2975 b2980 glcC glcC yghN 12.01 19.03 81.27 47.29 0.524 0.471 0.442 0.504 15.11 13.56 12.72 14.52 28.81 9.54 r "DNA-binding transcriptional dual regulator, glycolate-binding" Cytoplasmic 46785; Winged helix JW2970 ECK2995 b3001 yghZ yghZ mgrA 8.08 14.48 93.54 25.58 0.911 0.911 1.115 1.193 35.36 35.35 43.27 46.28 38.795 7.81 e aldo-keto reductase Cytoplasmic 51430; NAD(P)-linked oxidoreductase JW2975 ECK3000 b3008 metC metC ecfA 21.88 42.74 83.73 87.05 0.259 0.254 0.319 0.25 11.19 10.96 13.79 10.79 43.169 6.49 e "cystathionine beta-lyase, PLP-dependent" Cytoplasmic 1CL2 53383; PLP-dependent transferases JW2987 ECK3010 b3019 parC parC 27.29 67.93 30.65 74.17 0.144 0.189 0.161 0.193 12.09 15.87 13.45 16.15 83.743 6.66 e "DNA topoisomerase IV, subunit A" Cytoplasmic 56719; Type II DNA topoisomerase JW2999 ECK3022 b3031 yqiA yqiA yzzI 15.82 23.89 71.29 61.29 1.463 1.352 1.436 1.235 31.62 29.21 31.04 26.69 21.61 5.3 pe predicted esterase Cytoplasmic 53474; alpha/beta-Hydrolases JW3001 ECK3024 b3033 yqiB yqiB yzzH 21.87 41.9 50.85 59.53 1.452 2.06 2.158 1.857 24.01 34.06 35.69 30.71 16.537 9.45 pe predicted dehydrogenase Cytoplasmic JW3032 ECK3050 b3060 ygiP ygiP 18.96 32.9 36.46 49.42 1.107 1.124 1.227 1.069 39.05 39.64 43.3 37.7 35.278 6.77 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW3036 ECK3054 b3064 ygjD ygjD gcp 13.93 23 71.03 65.27 1.484 1.197 1.558 1.333 53.36 43.06 56.05 47.94 35.969 6.72 pe predicted peptidase Cytoplasmic 53067; Actin-like ATPase domain JW3040 ECK3058 b3068 ygjF ygjF mug -!- tdg -!- dug 33.62 45.98 83.84 89.43 4.261 3.296 4.426 4.274 79.51 61.5 82.59 79.75 18.659 9.76 e G/U mismatch-specific DNA glycosylase Cytoplasmic 1MWJ 52141; DNA glycosylase JW3041 ECK3060 b3070 yqjH yqjH 14.46 18.01 68.05 53.96 1.189 1.171 1.331 1.38 34.28 33.78 38.38 39.79 28.839 6.27 pc predicted siderophore interacting protein Cytoplasmic "52343; Ferredoxin reductase-like, C-terminal NADP-linked domain -!- 63380; Riboflavin synthase domain-like" JW3048 ECK3067 b3077 ebgC ebgC 21.67 22.05 52.45 113.02 3.089 2.814 3.043 2.964 53.86 49.08 53.07 51.69 17.437 6.35 e "cryptic beta-D-galactosidase, beta subunit" Cytoplasmic JW3052 ECK3071 b3081 fadH fadH ygjL 12.39 34.62 49.81 86.85 0.295 0.33 0.256 0.262 21.45 23.92 18.57 19.05 72.605 6.46 e "2,4-dienoyl-CoA reductase, NADH and FMN-linked" Cytoplasmic 51395; FMN-linked oxidoreductases JW3054 ECK3073 b3083 ygjN ygjN 17.75 37.21 30.64 126.63 3.09 2.924 3.741 3.782 37.4 35.39 45.26 45.77 12.101 10.12 o conserved protein Cytoplasmic JW3063 ECK3083 b3092 uxaC uxaC homH -!- homh -!- ygjX -!- ygjY -!- ygjZ 7.61 12.78 65.49 67.87 1.22 1.186 1.643 1.473 65.81 63.97 88.59 79.45 53.925 5.83 e uronate isomerase Cytoplasmic JW3065 ECK3085 b3094 exuR exuR 20.32 21.02 23.79 43.11 1.882 2.043 2.152 1.711 56.1 60.88 64.13 51 29.801 5.98 r DNA-binding transcriptional repressor Cytoplasmic 46785; Winged helix JW3073 ECK3093 b3102 yqjG yqjG 15.29 26.2 88.25 66.69 0.794 0.822 0.858 0.76 29.65 30.7 32.06 28.4 37.35 6.5 pe predicted S-transferase Cytoplasmic "47616; Glutathione S-transferases, C-terminal domain" JW3076 ECK3096 b3105 yhaJ yhaJ 21.45 28.55 63.04 58.87 2.368 2.947 2.788 2.423 78.68 97.91 92.62 80.5 33.22 6.98 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW3091 ECK3109 b3120 yhaB yhaB 13 14.24 40.89 26.53 0.869 1.186 1.166 1.103 17.86 24.38 23.97 22.67 20.559 7.28 o predicted protein Cytoplasmic JW3106 ECK3125 b3137 kbaY kbaY kba -!- agaY -!- csdA -!- yraC 17.93 23.09 86.86 66.17 1.241 1.381 1.612 2.124 38.81 43.15 50.38 66.38 31.257 5.98 e "tagatose 6-phosphate aldolase 1, kbaY subunit" Cytoplasmic 1GVF 51569; Aldolase JW3127 ECK3146 b3158 yhbU yhbU 10.51 24.24 90.44 83.97 0.377 0.348 0.391 0.28 13.96 12.9 14.46 10.36 37.015 7.31 pe predicted peptidase (collagenase-like) Cytoplasmic JW3129 ECK3148 b3160 yhbW yhbW 10.41 20.13 72.39 51.52 0.403 0.535 0.525 0.381 14.95 19.83 19.47 14.12 37.093 6.5 pe predicted enzyme Cytoplasmic 51679; Bacterial luciferase-like JW3140 ECK3161 b3172 argG argG Arg6 -!- argE 17.44 37.91 72.63 76.17 0.857 1.022 1.024 1.003 42.72 50.95 51.05 49.98 49.837 5.63 e argininosuccinate synthetase Cytoplasmic 1KP3 "52402; Adenine nucleotide alpha hydrolases -!- 69864; Argininosuccinate synthetase, C-terminal domain" JW3144 ECK3166 b3177 folP folP dhpS 47.7 55.48 104.56 89.43 1.058 1.183 1.515 1.725 32.36 36.18 46.32 52.75 30.582 6.22 e "7,8-dihydropteroate synthase" Cytoplasmic 1AJZ 51717; Dihydropteroate synthetase-like JW3146 ECK3168 b3179 rrmJ rrmJ ftsJ -!- mrsF 13.88 17.64 43.49 49.11 3.293 3.902 3.899 3.731 76.78 90.97 90.92 86.99 23.316 10.02 e 23S rRNA methyltransferase Cytoplasmic 1EJ0 53335; S-adenosyl-L-methionine-dependent methyltransferases JW3162 ECK3184 b3195 yrbF yrbF 14.57 48.97 93.15 76.3 0.854 0.735 1.015 1.008 24.84 21.35 29.51 29.29 29.067 7.02 pt predicted toluene transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW3168 ECK3190 b3201 yhbG yhbG 17.14 26.65 97.56 79.94 2.832 2.631 2.935 3.054 75.81 70.43 78.57 81.76 26.771 6.32 pt predicted transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW3178 ECK3201 b3211 yhcC yhcC 10.98 19.42 76.86 40.03 1.255 1.471 1.777 1.354 43.42 50.88 61.46 46.83 34.582 7.92 pe predicted Fe-S oxidoreductase Cytoplasmic JW3180 ECK3203 b3213 gltD gltD aspB -!- ossB -!- psiQ 18.06 35.57 43.44 92.62 2.372 1.681 2.087 2.285 123.22 87.35 108.45 118.72 51.954 6.05 c "glutamate synthase, 4Fe-4S protein, small subunit" Cytoplasmic 46548; alpha-helical ferredoxin JW3189 ECK3209 b3220 yhcG yhcG 15.51 28.12 57.96 104.06 0.672 0.622 0.828 0.837 29.08 26.91 35.81 36.2 43.252 7.09 o conserved protein Cytoplasmic JW3194 ECK3214 b3225 nanA nanA npl 12.27 18.14 88.57 65.76 0.961 1.081 1.25 1.125 31.28 35.18 40.68 36.62 32.556 6.47 e N-acetylneuraminate lyase Cytoplasmic 1HL2 51569; Aldolase JW3224 ECK3243 b3256 accC accC fabG 36.9 67.02 102.6 107.46 1.825 1.747 1.689 1.476 89.92 86.09 83.21 72.71 49.274 7.26 e "acetyl-CoA carboxylase, biotin carboxylase subunit" Cytoplasmic 1DV1 52440; Biotin carboxylase N-terminal domain-like -!- 56059; Glutathione synthetase ATP-binding domain-like JW3228 ECK3247 b3260 dusB dusB yhdG 9.92 15.57 38.3 22.04 3.994 3.591 4.137 4.096 143.1 128.68 148.23 146.77 35.83 6.99 e tRNA-dihydrouridine synthase B Cytoplasmic 51395; FMN-linked oxidoreductases JW3239 ECK3258 b3271 yhdZ yhdZ 10.47 14.21 81.1 47.4 2.289 2.136 2.457 1.989 65.34 60.99 70.14 56.8 28.55 7.33 pt predicted amino-acid transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW3288 ECK3313 b3326 gspE gspE yheG 8.06 13.17 21.57 80.27 1.163 1.333 1.394 1.48 63.44 72.7 76.04 80.72 54.552 6.36 pt "general secretory pathway component, cryptic" Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW3316 ECK3341 b3353 yheT yheT 14.67 28.77 75.81 44.32 2.525 2.482 2.803 2.885 97.14 95.48 107.82 110.99 38.466 7.8 pe predicted hydrolase Cytoplasmic 53474; alpha/beta-Hydrolases JW3322 ECK3347 b3359 argD argD Arg1 -!- argG -!- dapC -!- dtu 31.07 50.04 79.8 72.74 2.518 2.511 2.804 2.739 110.09 109.8 122.59 119.77 43.722 6.22 e bifunctional acetylornithine aminotransferase -!- succinyldiaminopimelate aminotransferase Cytoplasmic 53383; PLP-dependent transferases JW3324 ECK3349 b3361 fic fic 9.9 12.12 32.23 61.5 1.972 2.587 3.082 2.239 45.22 59.33 70.66 51.34 22.931 5.95 cp "stationary-phase protein, cell division" Cytoplasmic JW3328 ECK3353 b3365 nirB nirB 17.45 29.49 38.15 82.06 0.122 0.157 0.145 0.143 11.35 14.62 13.48 13.27 93.02 6.04 e "nitrite reductase, large subunit, NAD(P)H-binding" Cytoplasmic "51905; FAD/NAD(P)-binding domain -!- 55124; Sulfite reductase, domains 1 and 3 -!- 55424; FAD/NAD-linked reductases, dimerisation (C-terminal) domain -!- 56014; Sulfite reductase hemoprotein (SiRHP), domains 2 and 4" JW3339 ECK3363 b3376 yhfS yhfS 9.56 24.91 53.13 69.25 1.624 1.28 2.016 1.914 62.63 49.35 77.73 73.8 38.56 7.27 d conserved protein Cytoplasmic 53383; PLP-dependent transferases JW3352 ECK3376 b3389 aroB aroB 15.64 24.41 88.14 77.53 1.632 1.287 1.743 1.543 63.39 49.97 67.68 59.94 38.837 6.4 e 3-dehydroquinate synthase Cytoplasmic 56796; Dehydroquinate synthase-like JW3374 ECK3398 b3411 yhgA yhgA 26.27 34.12 50.42 73.31 2.746 2.426 3.024 2.73 91.24 80.62 100.48 90.72 33.233 6.52 ph predicted transposase Cytoplasmic JW3381 ECK3405 b3418 malT malT malA 8.47 11.85 18.93 89.26 0.079 0.13 0.124 0.1 8.14 13.38 12.79 10.25 103.019 6.23 r "DNA-binding transcriptional activator, maltotriose-ATP-binding" Cytoplasmic "52540; P-loop containing nucleotide triphosphate hydrolases -!- 46894; C-terminal, effector domain of the bipartite response regulators -!- 48452; TPR-like" JW3384 ECK3407 b3421 rtcB rtcB yhgL 27.43 61.23 125.66 107.21 0.448 0.364 0.494 0.505 20.23 16.43 22.33 22.81 45.174 6.43 d conserved protein Cytoplasmic 53383; PLP-dependent transferases JW3385 ECK3408 b3422 rtcR rtcR yhgB 8.04 16.74 29.58 47.37 0.506 0.393 0.573 0.591 30.48 23.66 34.53 35.6 60.24 7.3 r sigma 54-dependent transcriptional regulator of rtcBA expression Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW3386 ECK3409 b3423 glpR glpR 17.66 28.22 47.14 75.91 2.205 1.939 3.295 2.341 61.79 54.32 92.31 65.6 28.02 6.36 r DNA-binding transcriptional repressor Cytoplasmic 46785; Winged helix JW3391 ECK3414 b3428 glgP glgP glgY 9.38 17.53 13.26 74.08 0.133 0.18 0.153 0.173 12.36 16.78 14.25 16.1 93.069 5.8 e glycogen phosphorylase Cytoplasmic 53756; UDP-Glycosyltransferase/glycogen phosphorylase JW3392 ECK3415 b3429 glgA glgA 21.21 102.77 62.49 92.71 0.426 0.393 0.513 0.51 22.5 20.73 27.08 26.93 52.771 6.58 e glycogen synthase Cytoplasmic 53756; UDP-Glycosyltransferase/glycogen phosphorylase JW3393 ECK3416 b3430 glgC glgC 12.69 19.39 54.97 74.89 1.289 1.452 1.701 2.001 62.72 70.61 82.75 97.34 48.644 6.29 e glucose-1-phosphate adenylyltransferase Cytoplasmic 53448; Nucleotide-diphospho-sugar transferases JW3394 ECK3417 b3431 glgX glgX 25.58 58.65 85.01 75.59 0.11 0.115 0.144 0.155 8.05 8.48 10.55 11.41 73.501 5.9 e glycogen debranching enzyme Cytoplasmic 51445; (Trans)glycosidases JW3395 ECK3418 b3432 glgB glgB 7.44 50.55 85.69 76.26 0.06 0.041 0.021 0.051 5.06 3.48 1.74 4.28 84.255 6.14 e "1,4-alpha-glucan branching enzyme" Cytoplasmic 1M7X 48726; Immunoglobulin -!- 51445; (Trans)glycosidases JW3396 ECK3419 b3433 asd asd dap -!- hom 12.42 21.47 79.77 93.82 1.886 1.446 2.111 1.049 75.4 57.79 84.39 41.94 39.97 6.16 e "aspartate-semialdehyde dehydrogenase, NAD(P)-binding" Cytoplasmic 1GL3 "51735; NAD(P)-binding Rossmann-fold domains -!- 55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain" JW3406 ECK3428 b3442 yhhZ yhhZ 10.12 32.09 44.92 81 0.51 0.482 0.58 0.654 22.52 21.29 25.64 28.92 44.195 9.29 o conserved protein Cytoplasmic JW3415 ECK3434 b3450 ugpC ugpC 11.74 18.45 57.86 55.6 2.123 1.643 2.336 1.78 83.82 64.86 92.22 70.3 39.487 8.43 t glycerol-3-phosphate transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 50331; MOP-like -!- 52540; P-loop containing nucleotide triphosphate hydrolases JW3419 ECK3438 b3454 livF livF 15.57 21.12 81.82 39.15 4.25 4.104 4.693 3.845 111.69 107.85 123.32 101.05 26.28 6.48 t leucine/isoleucine/valine transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW3420 ECK3439 b3455 livG livG hrbB -!- hrbC -!- hrbD 9.31 17.82 65.37 50.94 1.167 1.303 1.569 1.054 33.13 37.01 44.55 29.94 28.4 7.82 t leucine/isoleucine/valine transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW3428 ECK3447 b3463 ftsE ftsE 12.31 24.96 71.25 50.86 2.593 1.962 2.645 2.191 63.33 47.92 64.61 53.5 24.425 10.04 pt predicted transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW3440 ECK3459 b3475 acpT acpT yhhU 12.64 16.88 43.32 38.3 1.983 1.804 2.114 1.927 43.11 39.22 45.96 41.89 21.743 6.35 e holo-(acyl carrier protein) synthase 2 Cytoplasmic 56214; 4'-phosphopantetheinyl transferase; possibly related to the IspF and YjgF-like s JW3455 ECK3473 b3488 yhiJ yhiJ 8.77 15.48 45.04 75.49 0.351 0.301 0.363 0.411 21.47 18.4 22.19 25.12 61.102 6.51 o predicted protein Cytoplasmic JW3466 ECK3484 b3499 yhiR yhiR 11.64 18.83 78.92 53.48 3.669 3.178 2.803 2.913 117.11 101.43 89.46 92.97 31.918 9.42 pe predicted DNA (exogenous) processing protein Cytoplasmic 53335; S-adenosyl-L-methionine-dependent methyltransferases JW3468 ECK3486 b3501 arsR arsR arsE 15.57 18.3 14.49 16.01 3.785 4.105 4.176 3.914 50.12 54.35 55.29 51.83 13.242 8.19 r DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix JW3471 ECK3489 b3504 yhiS yhiS 17.99 27.98 39.99 85.28 1.235 1.236 1.201 1.277 36.33 36.34 35.31 37.55 29.413 5.92 o predicted protein Cytoplasmic JW3483 ECK3499 b3515 gadW gadW yhiW 5.52 15.91 32.84 38.84 1.449 1.692 1.822 1.7 40.59 47.39 51.04 47.61 28.01 8.85 r DNA-binding transcriptional activator Cytoplasmic 46689; Homeodomain-like JW3488 ECK3505 b3520 yhjB yhjB 22.66 34.42 49.62 78.94 1.565 1.591 1.73 1.25 35.34 35.93 39.06 28.24 22.58 7.79 pr predicted DNA-binding response regulator in two-component regulatory system Cytoplasmic "46894; C-terminal, effector domain of the bipartite response regulators -!- 52172; CheY-like" JW3489 ECK3506 b3521 yhjC yhjC 8.72 14.67 36.31 37.01 1.298 1.524 1.72 1.226 46.79 54.96 62.01 44.21 36.063 8.45 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW3493 ECK3510 b3525 yhjH yhjH 7.54 16.79 49.13 34.17 0.9 1.037 1.267 1.007 26.6 30.67 37.48 29.79 29.569 6.93 r EAL domain containing protein involved in flagellar function Cytoplasmic JW3504 ECK3521 b3536 bcsE bcsE yhjS 18.26 33.39 85.39 91.36 1.013 0.662 0.933 0.741 60.12 39.29 55.38 44.01 59.367 6.6 o conserved protein Cytoplasmic JW3509 ECK3527 b3540 dppF dppF dppE 14.5 25.7 58.57 66.75 1.381 1.511 2.068 1.343 51.84 56.69 77.6 50.41 37.531 9.27 t dipeptide transporter -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW3510 ECK3528 b3541 dppD dppD 13.84 20.47 59.19 57.54 1.822 1.883 2.251 1.863 65.23 67.43 80.61 66.72 35.808 6.8 t dipeptide transporter -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW3519 ECK3537 b3550 yiaC yiaC 13.49 29.98 58.53 52.11 3.274 3.038 2.994 2.338 55.94 51.91 51.15 39.95 17.087 7.8 pe predicted acyltransferase with acyl-CoA N-acyltransferase domain Cytoplasmic 55729; Acyl-CoA N-acyltransferases (Nat) JW3536 ECK3553 b3564 xylB xylB 13.06 15.07 76.14 88.14 0.742 0.988 1.015 0.999 39 51.94 53.35 52.49 52.558 5.99 e xylulokinase Cytoplasmic 53067; Actin-like ATPase domain JW3541 ECK3558 b3569 xylR xylR 38.18 41.57 64.17 69.69 1.098 1.106 1.2 0.944 49.23 49.56 53.8 42.33 44.825 6.62 r "DNA-binding transcriptional activator, xylose-binding" Cytoplasmic 46689; Homeodomain-like -!- 53822; Periplasmic binding protein-like I JW3548 ECK3565 b3576 yiaL yiaL 5.63 10.36 25.53 63.91 4.766 4.075 4.489 3.996 83.54 71.43 78.69 70.03 17.528 6.3 o conserved protein Cytoplasmic JW3552 ECK3569 b3580 lyxK lyxK lyx -!- yiaP -!- sgbK -!- xylK 13.23 19.76 57.78 76 1.071 0.946 1.345 1.059 59.01 52.14 74.12 58.35 55.096 6.04 e L-xylulose kinase Cytoplasmic 53067; Actin-like ATPase domain JW3579 ECK3594 b3604 lldR lldR lctR -!- lct 9.46 16.86 20.79 38.6 2.684 2.925 2.656 2.543 78.23 85.23 77.39 74.1 29.141 7.15 r DNA-binding transcriptional repressor Cytoplasmic 46785; Winged helix JW3580 ECK3595 b3605 lldD lldD lct -!- lctD 5.59 10.27 45.96 38.8 1.69 2.061 1.963 1.425 72.15 87.96 83.77 60.84 42.683 7.32 e "L-lactate dehydrogenase, FMN-linked" Cytoplasmic 51395; FMN-linked oxidoreductases JW3590 ECK3605 b3615 yibD yibD 5.26 9.73 27.6 37.78 1.533 1.954 1.754 1.745 62.09 79.14 71.04 70.66 40.5 9.85 pe predicted glycosyl transferase Cytoplasmic 53448; Nucleotide-diphospho-sugar transferases JW3594 ECK3609 b3619 rfaD rfaD htrM -!- gmhD -!- nbsB -!- waaD -!- hldD 37.86 54.58 95.68 116.51 0.774 0.806 0.958 0.829 26.96 28.09 33.36 28.89 34.844 5.12 e "ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding" Cytoplasmic 1EQ2 51735; NAD(P)-binding Rossmann-fold domains JW3595 ECK3610 b3620 rfaF rfaF waaF 12.3 20.67 84.34 58.23 3.108 2.538 2.756 2.769 121.25 99 107.5 108 39.007 7.85 e ADP-heptose:LPS heptosyltransferase II Cytoplasmic JW3599 ECK3614 b3624 rfaZ rfaZ waaZ 23.8 33.19 48.29 104.84 0.622 0.664 0.633 0.637 20.45 21.85 20.82 20.95 32.898 9.68 pe lipopolysaccharide core biosynthesis protein Cytoplasmic JW3608 ECK3623 b3633 kdtA kdtA waaA 9.89 31.03 22.25 45.16 2.405 2.204 2.194 2.298 113.67 104.19 103.7 108.63 47.264 10.35 e 3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase) Cytoplasmic 53756; UDP-Glycosyltransferase/glycogen phosphorylase JW3622 ECK3637 b3647 ligB ligB yicF 21.25 32.07 41.32 59.04 0.149 0.183 0.212 0.189 9.39 11.53 13.39 11.94 63.123 9.53 e "DNA ligase, NAD(+)-dependent" Cytoplasmic "47781; RuvA domain 2-like -!- 50249; Nucleic acid-binding proteins -!- 56091; DNA ligase/mRNA capping enzyme, catalytic domain" JW3625 ECK3640 b3650 spoT spoT 15.81 33.55 30.55 75.1 0.182 0.131 0.155 0.288 14.4 10.35 12.26 22.84 79.285 9.07 e "bifunctional (p)ppGpp synthetase II -!- guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase" Cytoplasmic 55174; Alpha-L RNA-binding motif JW3626 ECK3641 b3651 trmH trmH spoU 34.79 25.84 96.66 79.59 2.389 1.842 2.384 2.039 60.49 46.64 60.37 51.64 25.321 7.72 e tRNA (Guanosine-2'-O-)-methyltransferase Cytoplasmic JW3646 ECK3662 b3671 ilvB ilvB 35.3 66.94 83.87 63.1 0.201 0.203 0.214 0.279 12.11 12.28 12.91 16.83 60.368 5.69 e "acetolactate synthase I, large subunit" Cytoplasmic 52467; DHS-like NAD/FAD-binding domain -!- 52518; Thiamin diphosphate-binding fold (THDP-binding) JW3650 ECK3665 b3674 yidF yidF 19.41 25.84 51.47 74.78 2.591 2.476 2.791 2.841 49.66 47.45 53.5 54.46 19.168 6.69 pr predicted DNA-binding transcriptional regulator Cytoplasmic JW3654 ECK3669 b3678 yidJ yidJ 18.49 23.46 66.78 69.45 1.988 1.607 1.797 2.091 113.79 91.97 102.82 119.65 57.226 5.51 pe predicted sulfatase/phosphatase Cytoplasmic 53649; Alkaline phosphatase-like JW3656 ECK3671 b3680 yidL yidL 14.46 33.03 42.77 76.36 1.027 0.984 1.038 0.987 36.15 34.64 36.52 34.75 35.199 8.28 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46689; Homeodomain-like JW3661 ECK3676 b3684 yidP yidP 9.02 25.21 26.88 28.96 4.166 3.802 4.444 3.967 113.76 103.82 121.37 108.33 27.309 10.08 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix JW3670 ECK3686 b3693 dgoK dgoK yidV 9.11 16.71 77.44 51.26 2.59 2.231 2.842 2.055 81.16 69.92 89.07 64.42 31.34 6.21 e 2-oxo-3-deoxygalactonate kinase Cytoplasmic 53067; Actin-like ATPase domain JW3677 ECK3692 b3700 recF recF uvrF 5.65 14.9 51.33 54 1.84 1.78 2.173 2.141 74.48 72.06 87.97 86.64 40.476 7.65 cp gap repair protein Cytoplasmic 52540; P-loop containing nucleoside triphosphate hydrolases JW3678 ECK3693 b3701 dnaN dnaN 18.24 20.65 59.99 87.53 2.859 3.165 3.347 3.505 115.91 128.29 135.69 142.08 40.536 5.81 e "DNA polymerase III, beta subunit" Cytoplasmic 1OK7 55979; DNA clamp JW3686 ECK3701 b3708 tnaA tnaA ind -!- tnaR 12.5 21.43 57.7 73.73 1.378 1.208 1.224 1.201 72.64 63.68 64.51 63.31 52.715 6.45 e "tryptophanase/L-cysteine desulfhydrase, PLP-dependent" Cytoplasmic 53383; PLP-dependent transferases JW3689 ECK3704 b3711 yidZ yidZ 5.59 13.87 59.65 34.74 1.898 1.997 1.854 1.767 69.93 73.57 68.33 65.11 36.848 7.93 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW3690 ECK3705 b3712 yieE yieE 8.37 15.23 43.92 39.66 3.77 3.916 4.096 3.651 106.21 110.32 115.4 102.84 28.171 8.2 pe predicted phosphopantetheinyl transferase Cytoplasmic 56214; 4'-phosphopantetheinyl transferase; possibly related to the IspF and YjgF-like s JW3693 ECK3708 b3715 yieH yieH 27.95 38.45 82.04 59.53 5.793 5.207 6.136 6.372 142.7 128.26 151.14 156.95 24.633 5.84 pe predicted hydrolase Cytoplasmic 56784; HAD-like JW3699 ECK3714 b3721 bglB bglB blgA 11.7 27.18 21.01 107.1 1.678 1.172 1.653 1.292 89.09 62.21 87.75 68.63 53.101 5.87 e cryptic phospho-beta-glucosidase B Cytoplasmic 51445; (Trans)glycosidases JW3703 ECK3718 b3725 pstB pstB phoT 16.56 15.06 78.34 80.73 2.036 2.282 2.793 2.108 59.03 66.18 80.97 61.11 28.996 7.24 t phosphate transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW3719 ECK3734 b3741 gidA gidA trmF 8.1 20.79 110.47 91.83 0.217 0.232 0.273 0.288 15.05 16.14 18.99 19.97 69.448 6.71 cp glucose-inhibited cell-division protein Cytoplasmic 51905; FAD/NAD(P)-binding domain JW3725 ECK3740 b3746 yieN yieN 15.01 45.86 67.04 77.41 0.449 0.431 0.492 0.413 25.28 24.27 27.69 23.27 56.329 6.56 pr fused predicted transcriptional regulators Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW3740 ECK3760 b3767 ilvG ilvG_1 ilvO 10.69 21.71 73.84 80.04 2.582 1.847 2.913 2.754 88.99 63.66 100.39 94.91 34.464 5.8 su "acetolactate synthase II, large subunit, N-ter fragment (pseudogene)" Cytoplasmic JW3741 ECK3760 b3768 ilvG ilvG_2 25.96 35.43 95.28 59.37 1.914 2.124 2.365 2.048 40.86 45.35 50.49 43.73 21.349 6.35 su "acetolactate synthase II, large subunit, C-ter fragment (pseudogene)" Cytoplasmic JW3746 ECK3765 b3773 ilvY ilvY 23.21 42.09 47.78 66.99 2.558 2.6 2.744 2.544 84.86 86.24 91.01 84.38 33.173 7.07 r DNA-binding transcriptional dual regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW3749 ECK3768 b3776 yifO yifO 9.9 20.01 14.37 56.61 4.611 3.663 3.928 4.27 49.22 39.1 41.93 45.58 10.674 11.56 o conserved protein Cytoplasmic JW3763 ECK3781 b3789 rffH rffH yifG -!- fcnB 15.77 23.54 79.51 70.84 1.452 1.314 1.637 1.201 47.48 42.97 53.51 39.25 32.694 6.19 e glucose-1-phosphate thymidylyltransferase Cytoplasmic 1MC3 53448; Nucleotide-diphospho-sugar transferases JW3765 ECK3783 b3791 rffA rffA wecE -!- yifI -!- rff 17.33 29.85 91.28 87.03 1.732 2.048 2.076 2.049 72.48 85.71 86.89 85.77 41.855 6.35 e TDP-4-oxo-6-deoxy-D-glucose transaminase Cytoplasmic 53383; PLP-dependent transferases JW3776 ECK3798 b3804 hemD hemD 23.32 50.92 96.23 95.95 1.029 0.903 1.034 0.833 28.57 25.08 28.71 23.13 27.769 6.75 e uroporphyrinogen III synthase Cytoplasmic "69618; Uroporphyrinogen III synthase (U3S, HemD)" JW3780 ECK3802 b3808 yzcX yzcX o161 15.3 37.11 44.58 76.01 1.449 1.291 1.657 1.265 25.11 22.37 28.71 21.92 17.327 7.98 o predicted protein Cytoplasmic JW3783 ECK3805 b3810 yigA yigA 15.98 30.43 52.88 63.04 2.495 3.415 3.297 2.925 66.63 91.18 88.03 78.11 26.703 6.68 o conserved protein Cytoplasmic JW3785 ECK3807 b3812 yigB yigB 27.73 37.57 89.46 41.36 0.658 1.068 1.148 0.919 17.83 28.94 31.09 24.9 27.094 6.77 pe predicted hydrolase Cytoplasmic 56784; HAD-like JW3786 ECK3808 b3813 uvrD uvrD dar-2 -!- dda -!- mutU -!- pdeB -!- rad -!- recL -!- srjC -!- uvr502 -!- uvrE 40.45 54.32 78.81 85.27 0.181 0.169 0.085 0.161 14.79 13.83 6.93 13.18 81.902 6.16 e DNA-dependent ATPase I and helicase II Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW3809 ECK3826 b3832 rmuC rmuC yigN 16.91 35.9 16.86 51.3 1.689 1.847 2.114 1.876 92.37 101.04 115.62 102.61 54.697 5.59 cp predicted recombination limiting protein Cytoplasmic JW3822 ECK3838 b3846 fadB fadB oldB 14.59 29.79 52.55 78.33 0.323 0.307 0.128 0.321 25.7 24.43 10.15 25.54 79.504 6.25 e fused 3-hydroxybutyryl-CoA epimerase/delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase/enoyl-CoA hydratase -!- 3-hydroxyacyl-CoA dehydrogenase Cytoplasmic 52096; ClpP/crotonase -!- 48179; 6-phosphogluconate dehydrogenase C-terminal domain-like -!- 51735; NAD(P)-binding Rossmann-fold domains JW3823 ECK3839 b3847 pepQ pepQ 11.86 17.01 93.29 77.31 1.732 2.451 2.92 2.709 86.83 122.85 146.36 135.78 50.122 5.98 e proline dipeptidase Cytoplasmic 55920; Creatinase/aminopeptidase JW3831 ECK3851 b3859 yihE yihE orfA 11.32 13.5 79.47 50.28 2.258 2.412 2.318 2.077 85.97 91.82 88.24 79.08 38.07 5.41 pe predicted kinase Cytoplasmic 56112; Protein kinase-like (PK-like) JW3834 ECK3854 b3862 yihG yihG 9.65 26.29 18.92 48.07 0.637 0.746 0.726 0.663 23.11 27.07 26.34 24.05 36.275 10.15 pe predicted endonuclease Cytoplasmic JW3850 ECK3872 b3879 yihR yihR 26.8 67.36 84.18 100.45 0.368 0.444 0.679 0.477 12.52 15.1 23.06 16.19 33.979 6.54 pe predicted aldose-1-epimerase Cytoplasmic JW3853 ECK3875 b3882 yihU yihU 14.07 12.48 70.33 68.22 2.011 2.586 2.806 1.983 62.58 80.47 87.34 61.73 31.124 6.72 pe predicted oxidoreductase with NAD(P)-binding Rossmann-fold domain Cytoplasmic 51735; NAD(P)-binding Rossmann-fold domains JW3866 ECK3888 b3895 fdhD fdhD 14.34 23.6 71.72 74.83 1.307 1.558 2.41 1.512 39.89 47.57 73.56 46.16 30.528 6.73 pf formate dehydrogenase formation protein Cytoplasmic JW3875 ECK3897 b3904 rhaB rhaB 5.06 19.5 53.15 76.28 1.357 1.217 1.356 1.318 73.29 65.74 73.22 71.16 54.001 5.39 e rhamnulokinase Cytoplasmic 53067; Actin-like ATPase domain JW3876 ECK3898 b3905 rhaS rhaS rhaC -!- rhaC2 30.57 66.32 77.28 83.97 0.589 0.804 0.948 0.772 19.01 25.97 30.61 24.94 32.289 6.6 r "DNA-binding transcriptional activator, L-rhamnose-binding" Cytoplasmic 46689; Homeodomain-like JW3895 ECK3916 b3924 fpr fpr mvrA -!- flxR 14.78 21.29 74.35 54.28 3.137 3.337 3.76 3.261 86.96 92.5 104.24 90.4 27.723 7.02 e ferredoxin-NADP reductase Cytoplasmic 1FDR "52343; Ferredoxin reductase-like, C-terminal NADP-linked domain -!- 63380; Riboflavin synthase domain-like" JW3897 ECK3918 b3926 glpK glpK 30.57 46.56 64.14 96.83 0.74 0.795 0.778 0.805 41.57 44.63 43.71 45.19 56.163 5.76 e glycerol kinase Cytoplasmic 1BOT 53067; Actin-like ATPase domain JW3913 ECK3933 b3941 metF metF 5.84 10.01 67.86 23.08 3.89 3.997 4.497 3.849 128.64 132.16 148.72 127.28 33.068 6.76 e "5,10-methylenetetrahydrofolate reductase" Cytoplasmic 1B5T 51730; Methylenetetrahydrofolate reductase JW3923 ECK3942 b3951 pflD pflD yijL 12.01 30.95 39.26 97.65 0.09 0.084 0.042 0.082 7.69 7.22 3.63 7.07 85.863 5.91 pe predicted formate acetyltransferase 2 (pyruvate formate lyase II) Cytoplasmic 51998; PFL-like glycyl radical enzymes JW3924 ECK3943 b3952 pflC pflC yijM 28.02 41 69.75 76.75 2.451 1.498 3.562 3.225 79.42 48.52 115.41 104.5 32.398 7.9 e pyruvate formate lyase II activase Cytoplasmic 46548; alpha-helical ferredoxin JW3926 ECK3945 b3954 yijO yijO 20.34 43.17 43.58 55.13 1.517 1.56 1.372 1.629 48.74 50.11 44.07 52.34 32.123 8.64 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46689; Homeodomain-like JW3933 ECK3953 b3961 oxyR oxyR momR -!- mor 14.77 31.94 35.64 65.39 2.118 2.05 2.742 2.684 72.52 70.18 93.88 91.89 34.241 6.46 r DNA-binding transcriptional dual regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW3935 ECK3955 b3963 fabR fabR yijC 6.07 10.32 18.36 25.34 3.926 4.003 4.252 4.049 104.16 106.18 112.8 107.41 26.528 9.77 r DNA-binding transcriptional repressor Cytoplasmic 46689; Homeodomain-like JW3957 ECK3985 b3993 thiE thiE thiA 17.19 30.9 89.92 107.57 1.527 1.331 1.616 1.566 35.12 30.59 37.15 35.99 22.989 6.48 e thiamin phosphate synthase (thiamin phosphate pyrophosphorylase) Cytoplasmic 51391; Thiamin phosphate synthase JW3958 ECK3986 b3994 thiC thiC 18.22 27.34 20.32 80 0.807 0.738 1.099 0.954 57.1 52.26 77.8 67.5 70.774 5.98 e thiamin (pyrimidine moiety) biosynthesis protein Cytoplasmic JW3961 ECK3989 b3997 hemE hemE hemC 9.89 21.17 108.1 60.51 0.818 0.71 0.691 0.69 32.08 27.83 27.09 27.04 39.206 6.49 e uroporphyrinogen decarboxylase Cytoplasmic "51726; Uroporphyrinogen decarboxylase, UROD" JW3976 ECK4008 b4016 aceK aceK 15.81 25.95 66.44 69.42 0.107 0.12 0.106 0.104 7.24 8.11 7.19 7.05 67.631 6.36 e isocitrate dehydrogenase kinase/phosphatase Cytoplasmic JW3978 ECK4010 b4018 iclR iclR 21.57 42.89 49.58 74.95 0.427 0.485 0.54 0.443 12.68 14.43 16.06 13.17 29.719 8.36 r DNA-binding transcriptional repressor Cytoplasmic 46785; Winged helix JW3995 ECK4027 b4035 malK malK malB 11.97 33.2 66.95 86.11 1.029 1.092 1.292 1.25 42.12 44.73 52.9 51.19 40.949 6.85 t "fused maltose transport subunit, ATP-binding component of ABC superfamily -!- regulatory protein" Cytoplasmic 1Q1E 52540; P-loop containing nucleotide triphosphate hydrolases -!- 50331; MOP-like JW3998 ECK4030 b4038 yjbI yjbI 16.15 26.86 63.99 93.24 0.26 0.27 0.273 0.272 13.44 13.96 14.12 14.03 51.652 6.2 o conserved protein Cytoplasmic JW4048 ECK4080 b4087 alsA alsA yjcW 16.33 41.94 52.53 98.6 0.408 0.373 0.423 0.384 23.15 21.14 24 21.75 56.689 7.55 t fused D-allose transporter subunits -!- ATP-binding components of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases -!- 52540; P-loop containing nucleotide triphosphate hydrolases JW4055 ECK4087 b4094 phnN phnN 8.29 17.25 33.75 46.56 2.408 2.395 2.973 2.416 49.9 49.61 61.6 50.05 20.717 8.73 e "ribose 1,5-bisphosphokinase" Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW4056 ECK4088 b4095 phnM phnM 6.8 11.69 50.73 36.1 2.306 2.038 2.79 2.411 96.79 85.56 117.11 101.2 41.972 6.44 e carbon-phosphorus lyase complex subunit Cytoplasmic 51338; Composite domain of metallo-dependent hydrolases JW4057 ECK4089 b4096 phnL phnL 14.28 26.17 61.49 56.25 2.197 1.834 2.272 1.777 54.24 45.28 56.09 43.87 24.687 9.58 e carbon-phosphorus lyase complex subunit Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW4059 ECK4091 b4098 phnJ phnJ 11.38 21.61 60.03 34.47 1.101 0.939 1.302 1.095 35.02 29.87 41.42 34.82 31.804 5.75 e carbon-phosphorus lyase complex subunit Cytoplasmic JW4060 ECK4092 b4099 phnI phnI 14.3 32.47 80.73 86.81 1.061 1.2 1.285 1.418 41.16 46.57 49.86 55.01 38.8 5.22 e carbon-phosphorus lyase complex subunit Cytoplasmic JW4062 ECK4094 b4101 phnG phnG 27.13 32.05 56.92 86.89 4.877 4.593 5.386 5.921 80.59 75.9 89 97.85 16.525 7.97 e carbon-phosphorus lyase complex subunit Cytoplasmic JW4063 ECK4095 b4102 phnF phnF 30.26 55.32 64.37 53.45 2.968 2.179 3.589 3.356 81.94 60.15 99.06 92.65 27.604 8.79 r transcriptional regulator of phosphonate uptake and biodegradation Cytoplasmic 46785; Winged helix JW4067 ECK4099 b4106 phnC phnC 13.32 22.43 61.31 43.73 2.613 2.412 2.376 2.571 76.87 70.94 69.9 75.62 29.416 10.29 t phosphonate/organophosphate ester transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW4070 ECK4102 b4109 yjdA yjdA 30.6 50.74 66.22 68.49 0.122 0.1 0.05 0.161 10.32 8.44 4.25 13.58 84.276 5.8 d conserved protein with nucleoside triphosphate hydrolase domain Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW4077 ECK4109 b4116 adiY adiY 10.81 18.1 53.19 64.97 0.99 0.742 0.941 0.713 28.69 21.51 27.27 20.68 28.984 8.26 r DNA-binding transcriptional activator Cytoplasmic 46689; Homeodomain-like JW4079 ECK4111 b4118 melR melR 11.92 22.21 23.77 48.77 1.344 1.217 1.657 1.322 46.92 42.46 57.82 46.13 34.902 8.66 r DNA-binding transcriptional dual regulator Cytoplasmic 46689; Homeodomain-like JW4080 ECK4112 b4119 melA melA mel-7 22.73 36.75 61.46 57.31 1.836 1.646 2.595 2.847 92.88 83.27 131.3 144.05 50.6 5.91 e "alpha-galactosidase, NAD(P)-binding" Cytoplasmic 51735; NAD(P)-binding Rossmann-fold domains JW4092 ECK4125 b4131 cadA cadA 16.76 73.84 102.09 84.69 0.077 0.061 0.007 0.075 6.25 4.94 0.58 6.06 81.176 6.19 e lysine decarboxylase 1 Cytoplasmic 53383; PLP-dependent transferases -!- 55904; Ornithine decarboxylase C-terminal domain JW4106 ECK4140 b4146 yjeK yjeK 13.99 19.01 77.58 58.18 2.482 2.448 2.667 2.377 96.09 94.76 103.25 92.03 38.712 6.61 pe predicted lysine aminomutase Cytoplasmic JW4124 ECK4162 b4166 yjeS yjeS 11.64 19.26 50.66 79.02 1.426 1.344 1.613 0.885 61.38 57.85 69.42 38.1 43.032 7.4 pc predicted Fe-S electron transport protein Cytoplasmic 54862; 4Fe-4S ferredoxins JW4129 ECK4167 b4171 miaA miaA trpX 20.72 29.06 81.39 86.75 1.91 1.929 2.22 2.021 66.9 67.56 77.75 70.77 35.026 6.32 e delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW4144 ECK4182 b4186 yjfC yjfC 8.13 19.18 64.27 66.72 1.674 1.234 1.575 1.356 75.23 55.49 70.78 60.95 44.951 4.7 pe predicted synthetase/amidase Cytoplasmic JW4149 ECK4187 b4191 ulaR ulaR yjfQ 16.84 23.78 58.49 55.1 3.434 2.928 3.758 2.967 94.7 80.73 103.64 81.82 27.577 8.98 r DNA-binding transriptional dual regulator Cytoplasmic 46785; Winged helix JW4156 ECK4194 b4198 ulaF ulaF sgaE -!- yjfX 13.16 18.63 72.57 31.22 4.931 4.388 6.766 5.226 124.54 110.82 170.88 132 25.256 6.73 e L-ribulose 5-phosphate 4-epimerase Cytoplasmic 53639; Class II aldolase JW4162 ECK4200 b4204 yjfZ yjfZ 9.72 17.19 51.99 22.24 2.336 2.076 2.487 2.042 69.4 61.69 73.88 60.68 29.711 7.01 o predicted protein Cytoplasmic JW4163 ECK4201 b4205 ytfA ytfA 18.17 28.85 32.96 78.59 1.977 1.7 2.531 2.05 24.2 20.81 30.98 25.09 12.24 8.23 pr predicted transcriptional regulator Cytoplasmic JW4194 ECK4230 b4235 pmbA pmbA mcb -!- tldE 15.15 29.67 57.07 79.78 1.311 1.182 1.543 1.162 63.32 57.09 74.57 56.13 48.313 5.9 pe predicted peptidase required for the maturation and secretion of the antibiotic peptide MccB17 Cytoplasmic JW4198 ECK4234 b4239 treC treC olgH -!- treE 26.59 61.55 73.62 61.82 0.26 0.191 0.309 0.263 16.6 12.16 19.73 16.76 63.767 5.86 e trehalose-6-P hydrolase Cytoplasmic "51011; alpha-Amylases, C-terminal beta-sheet domain -!- 51445; (Trans)glycosidases" JW4221 ECK4257 b4264 idnR idnR yjgS -!- gntH 5 14.75 30.91 31.52 1.445 1.498 1.627 1.367 54.25 56.2 61.05 51.31 37.53 6.84 r "DNA-binding transcriptional repressor, 5-gluconate-binding" Cytoplasmic 47413; lambda repressor-like DNA-binding domains -!- 53822; Periplasmic binding protein-like I JW4224 ECK4260 b4267 idnD idnD yjgV 24.85 27.26 67.62 94.23 1.968 2.234 2.667 2.399 73.05 82.9 98.98 89.02 37.108 6.42 e "L-idonate 5-dehydrogenase, NAD-binding" Cytoplasmic 50129; GroES-like -!- 51735; NAD(P)-binding Rossmann-fold domains JW4227 ECK4264 b4271 intB intB int(P4) -!- yjgC 7.68 19.88 26.79 79.16 1.233 1.065 1.413 1.286 56.18 48.52 64.36 58.57 45.559 10.08 h KpLE2 phage-like element; predicted integrase Cytoplasmic 56349; DNA breaking-rejoining enzymes JW4234 ECK4266 b4275 yjgX yjgX_2 yjgY 12.69 35.35 24.38 117.97 1.908 1.521 1.599 1.78 31.23 24.9 26.17 29.13 16.366 6.64 su "KpLE2 phage-like element; predicted protein, middle fragment (pseudogene)" Cytoplasmic 53649; Alkaline phosphatase-like JW4247 ECK4277 b4287 fecE fecE 16.62 18.78 45.91 20.13 3.825 3.211 3.467 3.848 107.73 90.44 97.66 108.37 28.167 8.48 h KpLE2 phage-like element; iron-dicitrate transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW4253 ECK4283 b4293 fecI fecI 22.59 28.85 42.67 86.96 2.787 2.788 1.937 2.413 54.24 54.26 37.69 46.95 19.459 6.92 h "KpLE2 phage-like element; RNA polymerase, sigma 19 factor" Cytoplasmic JW4259 ECK4286 b4297 yjhG yjhG 16.2 60.25 76.39 106.66 0.03 0.031 0.029 0.022 2.07 2.14 2.03 1.57 69.944 6.13 h KpLE2 phage-like element; predicted dehydratase Cytoplasmic JW4261 ECK4288 b4299 yjhI yjhI 13.99 23.13 60.96 42.95 2.234 1.765 2.574 2 66.69 52.7 76.84 59.7 29.854 9.01 h KpLE2 phage-like element; predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix JW4262 ECK4289 b4300 sgcR sgcR yjhJ 11.8 12.54 69.71 47.21 0.606 0.829 0.865 0.753 17.71 24.24 25.3 22.02 29.239 6.95 h KpLE2 phage-like element; predicted DNA-binding transcriptional regulator Cytoplasmic JW4263 ECK4290 b4301 sgcE sgcE yjhK 8.93 23.5 44.26 23.87 2.486 2.291 2.337 2.594 57.66 53.13 54.19 60.16 23.191 6.6 h KpLE2 phage-like element; predicted epimerase Cytoplasmic 51366; Ribulose-phoshate binding barrel JW4265 ECK4292 b4303 sgcQ sgcQ yjhM 7.35 14.91 67.68 29.68 0.876 0.894 1.087 0.747 25.69 26.22 31.87 21.91 29.321 6.35 h KpLE2 phage-like element; predicted nucleoside triphosphatase Cytoplasmic 51395; FMN-linked oxidoreductases JW4268 ECK4296 b4306 yjhP yjhP 9.05 12.03 51.63 42.55 3.372 2.88 3.703 3.23 92.1 78.66 101.15 88.23 27.316 5.46 h KpLE2 phage-like element; predicted methyltransferase Cytoplasmic 53335; S-adenosyl-L-methionine-dependent methyltransferases JW4272 ECK4300 b4309 yjhS yjhS 17.65 91.07 105.63 84.38 0.514 0.499 0.63 0.508 18.92 18.38 23.22 18.72 36.846 6.43 o conserved protein Cytoplasmic JW4276 ECK4304 b4313 fimE fimE pilH -!- hyp 9.19 17.76 39.88 47.4 2.977 3.064 3.095 3.394 68.79 70.81 71.52 78.43 23.108 10.41 r tyrosine recombinase/inversion of on/off regulator of fimA Cytoplasmic 56349; DNA breaking-rejoining enzymes JW4288 ECK4316 b4325 yjiC yjiC 18.12 36.95 67.86 64.74 2.063 2.105 2.154 1.958 63.04 64.33 65.82 59.84 30.56 6.56 o predicted protein Cytoplasmic JW4290 ECK4318 b4327 yjiE yjiE 25.79 60.91 76.43 66.69 0.363 0.402 0.425 0.381 12.58 13.93 14.73 13.19 34.672 6.24 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW4302 ECK4330 b4339 yjiQ yjiQ 25.72 39.01 81.93 79.84 1.961 2.353 2.643 2.681 42.65 51.18 57.48 58.3 21.746 6.96 ph predicted transposase Cytoplasmic JW4303 ECK4331 b4340 yjiR yjiR 5.27 19.05 28.86 56.15 1.487 1.317 1.904 1.474 78.82 69.81 100.93 78.14 53.003 8.18 pr fused predicted DNA-binding transcriptional regulator -!- predicted aminotransferase Cytoplasmic 46785; Winged helix -!- 53383; PLP-dependent transferases JW4314 ECK4341 b4351 mrr mrr mcrF 23.15 35.7 41 70.48 0.625 0.656 0.662 0.68 20.93 21.98 22.15 22.78 33.483 6.32 e methylated adenine and cytosine restriction protein Cytoplasmic JW4329 ECK4355 b4365 yjjQ yjjQ 23.99 30.76 75.95 75.04 0.731 0.886 0.718 0.822 19.74 23.94 19.39 22.2 27.009 8.19 pr predicted DNA-binding transcriptional regulator Cytoplasmic "46894; C-terminal, effector domain of the bipartite response regulators" JW4331 ECK4357 b4367 fhuF fhuF yjjS 36.48 58.37 51.17 96.97 1.885 1.885 1.961 1.606 56.71 56.71 58.99 48.32 30.083 6.65 c ferric iron reductase involved in ferric hydroximate transport Cytoplasmic JW4340 ECK4369 b4377 yjjU yjjU 4.46 20.24 72.48 41.8 0.794 0.753 1.034 1.332 31.6 29.97 41.14 52.99 39.794 8.76 pe predicted esterase Cytoplasmic JW4341 ECK4370 b4378 yjjV yjjV 13.39 21.45 91.25 30.46 1.355 1.244 1.552 1.676 39.13 35.94 44.83 48.4 28.881 6.82 pe predicted DNase Cytoplasmic 51556; Metallo-dependent hydrolases JW4345 ECK4374 b4382 deoA deoA tpp-75 -!- TP -!- tpp -!- ttg 13.73 22.12 85.95 83.14 1.469 1.596 2.059 2.347 69.24 75.24 97.06 110.64 47.148 5.74 e thymidine phosphorylase Cytoplasmic 47648; Pyrimidine nucleoside phosphorylase N-terminal domain -!- 52418; Pyrimidine nucleoside phosphorylase central domain -!- 54680; Pyrimidine nucleoside phosphorylase C-terminal domain JW4348 ECK4377 b4385 yjjJ yjjJ 10.53 27.85 78.47 90.14 0.455 0.571 0.638 0.72 22.62 28.38 31.72 35.8 49.703 6.6 pr predicted DNA-binding transcriptional regulator Cytoplasmic JW4352 ECK4381 b4389 radA radA sms -!- sms_1 32.09 51.89 96.3 99.7 0.877 1.053 1.437 2.076 43.36 52.07 71 102.61 49.424 7.46 cp predicted repair protein Cytoplasmic 48695; Multiheme cytochromes -!- 52540; P-loop containing nucleoside triphosphate hydrolases JW4359 ECK4388 b4396 rob rob cbpB -!- robA 16.84 40.08 58.06 50.4 2.497 2.472 3.194 3.299 82.67 81.86 105.76 109.24 33.113 7.71 r DNA-binding transcriptional activator Cytoplasmic 1D5Y 46689; Homeodomain-like -!- 55136; Probable bacterial effector-binding domain JW4366 ECK4395 b4403 yjtD lasT 28.29 38.02 77.38 76.14 3.918 3.174 4.757 3.79 98.85 80.08 120.02 95.63 25.231 6.31 pe predicted rRNA methyltransferase Cytoplasmic JW5004 ECK0036 b0035 caiE caiE 19.46 26.37 77.59 39.47 3.589 3.09 3.76 4.422 76.18 65.59 79.8 93.86 21.226 7.04 pe predicted acyl transferase Cytoplasmic 51161; Trimeric LpxA-like enzymes JW5010 ECK0131 b0132 yadD yadD 40.66 37.22 53.1 80.11 1.069 1.625 1.963 1.32 36.95 56.17 67.86 45.62 34.564 5.7 ph predicted transposase Cytoplasmic JW5013 ECK0161 b0162 cdaR cdaR yaeG -!- sdaR 12.34 14.64 48.46 78.85 1.646 1.973 2.022 1.291 71.82 86.1 88.25 56.36 43.642 7.06 r DNA-binding transcriptional regulator Cytoplasmic JW5017 ECK0209 b0209 yafD yafD 1.44 3.44 28.62 17.2 3.722 2.838 4.033 3.352 111.56 85.06 120.87 100.46 29.972 10.19 d conserved protein Cytoplasmic 56219; DNase I-like JW5037 ECK0300 b0300 ykgA ykgA 7.1 20.86 81.88 67.72 1.593 1.545 1.426 1.299 43.08 41.8 38.56 35.13 27.047 9.12 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46689; Homeodomain-like -!- 55136; Probable bacterial effector-binding domain JW5041 ECK0305 b0306 ykgE ykgE 10.12 12.49 61.79 69.36 3.176 2.741 2.835 2.406 82.52 71.2 73.66 62.5 25.978 7.79 pe predicted oxidoreductase Cytoplasmic JW5044 ECK0325 b0327 yahM yahM 19.61 58.88 65.6 81.86 2.311 2.119 2.056 2.349 20.54 18.84 18.28 20.88 8.889 11.22 o predicted protein Cytoplasmic JW5071 ECK0526 b0533 sfmH sfmH 15.3 44.37 65.33 97.07 1.355 1.044 1.175 1.343 48.04 37.02 41.65 47.59 35.445 5.32 ps predicted fimbrial-like adhesin protein Cytoplasmic 49401; Bacterial adhesins JW5091 ECK0637 b0644 ybeQ ybeQ 14.2 33.66 29.92 81.4 1.439 1.842 1.407 1.763 53.2 68.11 52.05 65.19 36.984 5.56 d conserved protein Cytoplasmic 48439; Protein prenylyltransferase JW5103 ECK0760 b0771 ybhJ ybhJ 19.09 19.77 83.94 87.48 0.735 0.496 0.575 0.764 59.86 40.41 46.79 62.21 81.409 5.69 pe predicted hydratase Cytoplasmic "52016; Aconitase, C-terminal domain -!- 53732; Aconitase, first 3 domains" JW5105 ECK0793 b0804 ybiX ybiX 15.46 24.47 53 56.64 1.812 1.778 1.942 1.593 46.22 45.35 49.53 40.62 25.503 6.77 o conserved protein Cytoplasmic JW5109 ECK0815 b0825 fsaA fsaA fsa -!- mipB -!- ybiZ 17.28 39.32 89.68 32.98 2.407 1.714 2.302 2.246 55.3 39.38 52.87 51.6 22.971 7.31 e fructose-6-phosphate aldolase 1 Cytoplasmic 51569; Aldolase JW5132 ECK0973 b0982 etp etp yccY -!- epd 21.43 37.21 54.01 96.13 3.63 2.848 3.564 3.611 59.45 46.64 58.37 59.14 16.378 10.01 e phosphotyrosine-protein phosphatase Cytoplasmic 52788; Phosphotyrosine protein phosphatases I JW5138 ECK0998 b1007 ycdH ycdH 10.27 23.29 77.55 47.23 1.842 1.546 2.268 1.643 32.66 27.42 40.22 29.12 17.732 7.14 pc "predicted oxidoreductase, flavin:NADH component" Cytoplasmic 50475; FMN-binding split barrel JW5145 ECK1016 b1028 ymdE ymdE 26.96 58.67 30.67 99.52 2.876 3.437 3.251 3.006 32.41 38.72 36.62 33.87 11.267 7.95 su predicted protein (pseudogene) Cytoplasmic 52151; Catalytic domain of malonyl-CoA ACP transacylase JW5150 ECK1032 b1046 ymdC ymdC 19.06 36.17 85.07 114.97 0.225 0.216 0.222 0.178 12.06 11.6 11.91 9.55 53.623 9.64 pe predicted hydrolase Cytoplasmic 56024; Phospholipase D/nuclease JW5154 ECK1070 b1085 yceQ yceQ 22.43 57.76 55.49 114.82 1.681 1.598 1.887 1.88 20.33 19.33 22.82 22.74 12.096 8.73 o predicted protein Cytoplasmic JW5156 ECK1076 b1090 plsX plsX 16.09 26.08 53.91 81.99 1.612 1.602 1.679 1.637 61.54 61.17 64.12 62.5 38.18 9.77 pe fatty acid/phospholipid synthesis protein Cytoplasmic JW5158 ECK1094 b1108 ycfP ycfP 12.7 20.37 52.24 57.92 1.977 1.874 2.165 1.904 41.93 39.74 45.92 40.38 21.207 6.81 o conserved protein Cytoplasmic 53474; alpha/beta-Hydrolases JW5162 ECK1103 b1117 lolD lolD ycfV 31 36.49 81.66 107.56 3.469 2.933 3.689 2.907 88.18 74.55 93.77 73.88 25.417 8.6 t outer membrane-specific lipoprotein transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW5165 ECK1118 b1132 hflD hflD ycfC -!- hslZ 21.21 56.76 65.34 72.68 2.842 2.348 2.808 2.455 65.17 53.85 64.39 56.29 22.931 9.97 pr predicted lysogenization regulator Cytoplasmic 1SDI JW5179 ECK1160 b4521 ymgH ymgH 13.67 81.8 23.41 120.86 6.086 5.337 6.313 6.789 51.6 45.24 53.52 57.56 8.478 10.29 o predicted protein Cytoplasmic JW5188 ECK1189 b1201 dhaR dhaR ptsD -!- ycgU 4.5 7.24 30.43 55.44 0.594 0.488 0.488 0.542 41.85 34.41 34.4 38.2 70.489 6.54 pr "predicted DNA-binding transcriptional regulator, dihydroxyacetone" Cytoplasmic 48283; FIS-like -!- 52540; P-loop containing nucleotide triphosphate hydrolases -!- 55785; PYP-like sensor domain JW5200 ECK1282 b1287 yciW yciW 8.3 19.81 82.68 80.27 0.679 0.678 0.741 0.718 28.65 28.6 31.26 30.28 42.176 6.51 pe predicted oxidoreductase Cytoplasmic JW5206 ECK1338 b1341 ydaM ydaM 20.57 29.25 78.96 87.5 0.617 0.778 0.781 0.809 28.62 36.11 36.24 37.55 46.412 6.75 pr "predicted diguanylate cyclase, GGDEF domain signalling protein" Cytoplasmic 55785; PYP-like sensor domain JW5226 ECK1416 b1422 ydcI ydcI 9.45 19.12 53.01 48.01 1.301 1.14 1.601 1.239 43.41 38.05 53.44 41.33 33.373 8.36 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW5238 ECK1473 b1479 sfcA sfcA mae -!- maeA 20.58 33.26 61.07 61.15 0.966 0.961 0.937 1.149 60.97 60.64 59.16 72.54 63.118 5.55 e "malate dehydrogenase, NAD-requiring (malic enzyme)" Cytoplasmic "51735; NAD(P)-binding Rossmann-fold domains -!- 53223; Aminoacid dehydrogenase-like, N-terminal domain" JW5241 ECK1484 b1490 yddV yddV 34.19 122.64 38.43 73.56 0.281 0.151 0.252 0.267 11.24 6.02 10.06 10.67 39.988 7.11 pr predicted diguanylate cyclase Cytoplasmic JW5249 ECK1524 b1531 marA marA cfxB -!- norB -!- soxQ -!- inaR -!- nfxC 12 25.94 25.91 104.76 5.107 4.835 5.134 5.43 77.51 73.38 77.91 82.4 15.177 10.03 r DNA-binding transcriptional dual regulator Cytoplasmic 1BL0 46689; Homeodomain-like JW5272 ECK1669 b1673 ydhV ydhV 27.92 40.83 62.62 81.78 0.084 0.141 0.127 0.163 6.53 10.94 9.92 12.65 77.799 6.68 pe predicted oxidoreductase Cytoplasmic "48310; Aldehyde ferredoxin oxidoreductase, C-terminal domains -!- 56228; Aldehyde ferredoxin oxidoreductase, N-terminal domain" JW5277 ECK1712 b1714 pheS pheS phe-act 15.15 25.79 77.7 90.32 2.377 1.953 2.049 1.578 87.47 71.85 75.38 58.06 36.793 6.33 e "phenylalanine tRNA synthetase, alpha subunit" Cytoplasmic 46589; A class II aminoacyl-tRNA synthetase N-domain -!- 55681; Class II aaRS and biotin synthetases JW5286 ECK1754 b1756 ynjD ynjD 10.01 29.58 104.94 65.03 0.78 0.927 0.685 0.639 18.72 22.23 16.43 15.33 23.989 7.23 pt predicted transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW5313 ECK1918 b1919 yedO yedO dcyD 6.14 18.28 67.07 50.8 1.665 1.428 1.584 1.566 58.47 50.12 55.62 54.98 35.106 5.4 e "D-cysteine desulfhydrase, PLP-dependent" Cytoplasmic 53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes JW5319 ECK1962 b1964 yedS yedS_1 yedT 19.56 93.79 34.73 65.38 3.369 3.847 3.954 3.084 58.2 66.45 68.29 53.27 17.272 5.97 su "predicted protein, N-ter fragment (pseudogene)" Cytoplasmic JW5327 ECK1991 b1999 yeeP yeeP 5.91 6.2 12.89 58.9 4.974 5.258 5.076 4.932 78.25 82.73 79.87 77.59 15.734 7.31 h CP4-44 prophage; predicted GTP-binding protein (pseudogene) Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW5328 ECK2000 b4538 yoeF yoeF 18.69 32.62 51.6 36.43 4.089 3.628 4.756 4.633 52.98 47.01 61.63 60.03 12.957 7.61 o conserved protein Cytoplasmic 52540; P-loop containing nucleoside triphosphate hydrolases JW5340 ECK2083 b2087 gatR gatR_1 25.66 32.47 86.92 64.81 1.481 1.203 1.869 1.471 23.45 19.04 29.58 23.29 15.832 7.94 su "DNA-binding transcriptional regulator, N-ter fragment (pseudogene)" Cytoplasmic JW5343 ECK2089 b2096 gatY gatY yegF 6.34 11.16 31.37 39.05 1.181 0.974 1.349 1.243 36.36 29.97 41.54 38.26 30.782 6.38 e "D-tagatose 1,6-bisphosphate aldolase 2, catalytic subunit" Cytoplasmic 51569; Aldolase JW5344 ECK2090 b2097 fbaB fbaB dhnA 8.58 13.03 58.72 26.33 0.936 1.158 1.122 0.798 35.64 44.07 42.7 30.37 38.071 7.02 e fructose-bisphosphate aldolase class I Cytoplasmic 51569; Aldolase JW5349 ECK2111 b2119 yehL yehL 17.38 28.85 93.88 117.98 0.705 0.574 0.994 0.68 27.94 22.74 39.41 26.96 39.641 6.79 pt predicted transporter subunit -!- ATP-binding compoents of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW5350 ECK2113 b2121 yehP yehP 12.85 27.83 51.95 51.35 0.982 0.956 1.047 1.021 41.32 40.24 44.05 42.94 42.075 6.52 d conserved protein Cytoplasmic 53300; Integrin A (or I) domain JW5372 ECK2246 b2253 yfbE yfbE arnB -!- pmrH 12.94 16.79 57.26 49.79 0.106 0.118 0.157 0.117 4.46 4.97 6.64 4.95 42.199 6.94 e "uridine 5'-(beta-1-threo-pentapyranosyl-4-ulose diphosphate) aminotransferase, PLP-dependent" Cytoplasmic 53383; PLP-dependent transferases JW5374 ECK2258 b2264 menD menD 9.95 22.82 83.32 85.86 0.435 0.5 0.507 0.499 26.66 30.64 31.11 30.58 61.307 6.46 e bifunctional 2-oxoglutarate decarboxylase -!- SHCHC synthase Cytoplasmic 52518; Thiamin diphosphate-binding fold (THDP-binding) JW5375 ECK2280 b2286 nuoC nuoC nuoCD -!- nuoD 19.05 40.24 75.51 101.76 0.216 0.251 0.275 0.282 14.79 17.26 18.9 19.36 68.624 6.32 c "NADH:ubiquinone oxidoreductase, chain C,D" Cytoplasmic "56762; Nickel-iron hydrogenase, large subunit" JW5384 ECK2349 b2355 yfdL yfdL 14.31 25.92 60.2 34.21 3.008 1.607 2.01 2.097 54.84 29.3 36.65 38.23 18.232 7.91 h CPS-53 (KpLE1) prophage; conserved protein Cytoplasmic JW5405 ECK2546 b2549 yphG yphG 4.87 10.12 80.71 100.25 0.045 0.053 0.048 0.043 5.6 6.61 5.88 5.26 123.698 5.86 d conserved protein Cytoplasmic 48452; TPR-like JW5406 ECK2547 b2550 yphH yphH 8.79 20.1 60.76 70.23 1.101 1.115 0.808 0.746 48.97 49.58 35.95 33.18 44.474 6.73 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix JW5416 ECK2612 b2616 recN recN radB 11.56 24.5 21.06 52.61 0.812 0.918 1.239 1.204 49.81 56.27 75.96 73.85 61.325 5.61 cp recombination and repair protein Cytoplasmic 52540; P-loop containing nucleoside triphosphate hydrolases JW5426 ECK2651 b2657 yqaC yqaC 10.66 28.24 48.83 80.48 2.285 2.064 2.083 1.748 52.26 47.2 47.64 39.99 22.873 8.88 su conserved protein (pseudogene) Cytoplasmic 51445; (Trans)glycosidases JW5434 ECK2709 b2714 ascG ascG sac 32.36 41.53 78.33 100.26 1.183 1.571 1.652 1.301 43.67 57.97 60.98 48.01 36.907 6.83 r DNA-binding transcriptional regulator Cytoplasmic 47413; lambda repressor-like DNA-binding domains -!- 53822; Periplasmic binding protein-like I JW5441 ECK2765 b2770 ygcR ygcR 20.86 31.96 64.19 50.27 1.216 1.236 1.426 0.979 34.88 35.46 40.92 28.08 28.69 7.49 pc predicted flavoprotein Cytoplasmic 52431; ETFP adenine nucleotide-binding domain-like JW5442 ECK2767 b4463 ygcU ygcU ygcT -!- ygcV 12.64 22.16 71.97 84.96 0.391 0.324 0.392 0.568 20.99 17.41 21.06 30.49 53.683 6.33 pe predicted FAD containing dehydrogenase Cytoplasmic JW5454 ECK2844 b2846 yqeH yqeH 11.19 21.71 30.8 28.18 1.352 1.263 1.396 1.396 32.81 30.66 33.86 33.86 24.264 7.7 d conserved protein with bipartite regulator domain Cytoplasmic "46894; C-terminal, effector domain of the bipartite response regulators" JW5457 ECK2852 b2854 pbl pbl ygeJ 11.67 25.73 41.89 76.05 2.657 2.178 3.032 2.571 38.48 31.54 43.91 37.23 14.48 10.08 su predicted peptidoglycan-binding enzyme (pseudogene) Cytoplasmic 53955; Lysozyme-like JW5458 ECK2853 b2855 ygeK ygeK 19.99 44.62 55.01 85.62 2.095 1.716 1.686 1.766 34.71 28.43 27.93 29.26 16.569 9.64 pr predicted DNA-binding transcriptional regulator Cytoplasmic "46894; C-terminal, effector domain of the bipartite response regulators -!- 52172; CheY-like" JW5462 ECK2862 b2866 xdhA xdhA ygeS 12.58 29.44 35.88 80.25 0.311 0.409 0.525 0.364 25.26 33.21 42.66 29.54 81.236 6.19 e "xanthine dehydrogenase, molybdenum binding subunit" Cytoplasmic 54665; CO dehydrogenase molybdoprotein N-domain-like -!- 56003; Molybdemum cofactor-binding domain JW5464 ECK2872 b2876 yqeC yqeC 24.15 35.87 95.36 73.03 0.893 0.802 0.882 0.86 25.08 22.51 24.75 24.14 28.08 7.46 d conserved protein Cytoplasmic "53623; MurD-like peptide ligases, catalytic domain" JW5469 ECK2882 b2887 ygfT ygfT 21.88 60.54 68.02 88 0.463 0.3 0.421 0.546 31.97 20.72 29.04 37.66 69.017 6.27 pe fused predicted oxidoreductase Fe-S subunit -!- nucleotide-binding subunit Cytoplasmic 54862; 4Fe-4S ferredoxins -!- 51971; Nucleotide-binding domain JW5476 ECK2917 b2921 ygfI ygfI 8.88 21.54 45.23 69.8 0.962 0.79 0.895 0.888 33.34 27.38 31.01 30.78 34.642 7.96 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix -!- 53850; Periplasmic binding protein-like II JW5482 ECK2960 b2965 speC speC 4.21 9.89 53.52 65.31 0.343 0.379 0.324 0.345 27.24 30.05 25.69 27.34 79.331 5.93 e "ornithine decarboxylase, constitutive" Cytoplasmic 53383; PLP-dependent transferases -!- 55904; Ornithine decarboxylase C-terminal domain JW5486 ECK2972 b4467 glcF glcF b2978 -!- yghL -!- gox 9.86 20.29 51.93 60.85 0.733 0.558 0.692 0.76 33.05 25.14 31.21 34.25 45.073 7.87 c glycolate oxidase iron-sulfur subunit Cytoplasmic JW5487 ECK2973 b4468 glcE glcE b2978 -!- yghL -!- gox 19.16 38.61 90.25 125.71 0.547 0.438 0.451 0.401 20.95 16.78 17.28 15.35 38.32 6.92 e glycolate oxidase FAD binding subunit Cytoplasmic JW5499 ECK3004 b3012 dkgA dkgA yqhE 25.75 42.82 96.22 74.85 0.498 0.528 0.582 0.486 15.47 16.42 18.08 15.09 31.078 6.65 e "2,5-diketo-D-gluconate reductase A" Cytoplasmic 51430; NAD(P)-linked oxidoreductase JW5501 ECK3007 b4469 ygiQ ygiQ ygiR 14.46 49.7 40.65 102.77 0.101 0.164 0.16 0.132 8.42 13.68 13.39 10.99 83.425 9.56 o conserved protein Cytoplasmic JW5502 ECK3014 b3023 ygiV ygiV 21.26 39.44 65.39 77.67 3.946 2.944 4.553 3.534 70.26 52.42 81.06 62.92 17.806 6.3 pr predicted transcriptional regulator Cytoplasmic 55136; Probable bacterial effector-binding domain JW5511 ECK3066 b3076 ebgA ebgA 18.62 25.76 28.72 93.71 0.043 0.053 0.055 0.048 5.03 6.29 6.53 5.62 117.742 5.38 e "cryptic beta-D-galactosidase, alpha subunit" Cytoplasmic 49303; beta-Galactosidase/glucuronidase domain -!- 49785; Galactose-binding domain-like -!- 51445; (Trans)glycosidases JW5520 ECK3101 b4471 tdcG tdcG yhaP -!- yhaQ 10.13 12.47 78.21 80.23 0.265 0.376 0.373 0.31 12.86 18.22 18.08 15.01 48.469 6.26 e L-serine dehydratase 3 Cytoplasmic JW5522 ECK3103 b3114 tdcE tdcE yhaS 21.35 28.52 16.18 71.89 0.328 0.447 0.79 0.6 28.13 38.38 67.79 51.48 85.837 5.75 e pyruvate formate-lyase 4/2-ketobutyrate formate-lyase Cytoplasmic 51998; PFL-like glycyl radical enzymes JW5527 ECK3123 b3135 agaA agaA yraA 11.64 16.36 59.79 25.56 4.862 4.629 5.658 5.303 85.11 81.05 99.05 92.84 17.507 7.28 pe predicted truncated N-acetylgalactosamine-6-phosphate deacetylase Cytoplasmic JW5528 ECK3140 b3152 yraR yraR 10.1 17.39 49.39 28.62 4.574 4.225 5.72 5.523 106.01 97.93 132.58 128.03 23.179 9.17 pe predicted nucleoside-diphosphate-sugar epimerase Cytoplasmic 51735; NAD(P)-binding Rossmann-fold domains JW5530 ECK3147 b3159 yhbV yhbV 11.19 22.71 83.14 50.34 2.212 2.176 2.382 3.583 71.89 70.72 77.39 116.43 32.494 6.09 pe predicted protease Cytoplasmic JW5543 ECK3249 b3262 yhdJ yhdJ ccrM 12.57 32.53 74.5 64.3 1.496 1.347 1.902 1.772 49.94 44.93 63.48 59.14 33.37 9.33 pe predicted methyltransferase Cytoplasmic 53335; S-adenosyl-L-methionine-dependent methyltransferases JW5547 ECK3990 b3998 nfi nfi yjaF 20.88 31.03 80.92 43.8 3.279 3.204 4.043 2.735 80.84 78.99 99.67 67.41 24.65 8.68 e endonuclease V Cytoplasmic JW5549 ECK3982 b3991 thiG thiG thiA -!- thiB 13.56 23.61 96.33 76.07 2.046 1.694 2.212 1.997 54.95 45.52 59.41 53.66 26.864 6.21 pe thiamin biosynthesis ThiGH complex subunit Cytoplasmic JW5551 ECK3954 b3962 sthA sthA udhA -!- sth 21.31 25.45 55.63 60.56 2.633 2.063 2.357 2.174 135.62 106.28 121.39 111.97 51.513 6.42 e "pyridine nucleotide transhydrogenase, soluble" Cytoplasmic "51905; FAD/NAD(P)-binding domain -!- 55424; FAD/NAD-linked reductases, dimerisation (C-terminal) domain" JW5569 ECK3873 b3880 yihS yihS 18.55 30.49 50.65 84.52 1.034 0.901 1.009 1.015 48.99 42.69 47.82 48.09 47.383 6.11 pe predicted glucosamine isomerase Cytoplasmic 48208; Six-hairpin glycosyltransferases JW5578 ECK3837 b3845 fadA fadA oldA 8.42 14.39 88.81 31.79 1.702 1.472 1.828 1.431 69.52 60.13 74.64 58.44 40.837 6.87 e 3-ketoacyl-CoA thiolase (thiolase I) Cytoplasmic 53901; Thiolase-like JW5588 ECK3814 b3820 yigI yigI 8.74 13.56 67.13 53.73 3.23 2.898 3.282 3.096 55.38 49.68 56.27 53.09 17.146 7.95 o conserved protein Cytoplasmic JW5592 ECK3804 b3809 dapF dapF 21.09 40.81 70.75 63.11 3.467 2.959 3.836 2.921 104.62 89.3 115.77 88.13 30.177 6.48 e diaminopimelate epimerase Cytoplasmic 54506; Diaminopimelate epimerase JW5594 ECK3793 b3800 aslB aslB atsB -!- gppB 13.19 21.43 57.94 71.9 0.639 0.617 0.789 0.67 29.7 28.67 36.66 31.12 46.476 6.85 pr predicted regulator of arylsulfatase activity Cytoplasmic JW5597 ECK3782 b3790 rffC rffC wecD -!- yifH -!- rff 9.46 26.98 47.77 63.54 3.558 3.38 3.326 3.686 69.47 65.99 64.94 71.97 19.525 9.06 e TDP-fucosamine acetyltransferase Cytoplasmic 55729; Acyl-CoA N-acyltransferases (Nat) JW5604 ECK3770 b3778 rep rep dasC -!- mbrA -!- mmrA 17.11 70.85 87.4 84.43 0.05 0.059 0.045 0.045 3.85 4.55 3.45 3.44 76.949 7.38 e DNA helicase and single-stranded DNA-dependent ATPase Cytoplasmic 1UAA 52540; P-loop containing nucleotide triphosphate hydrolases JW5605 ECK3763 b3771 ilvD ilvD 33.49 48.91 58.84 72.72 0.336 0.323 0.356 0.357 21.99 21.14 23.3 23.35 65.457 6.05 e dihydroxyacid dehydratase Cytoplasmic JW5607 ECK3756 b4480 hdfR hdfR yifA -!- yifD 8.76 19.16 52.73 50.89 1.839 1.692 1.681 1.963 58.33 53.66 53.32 62.28 31.718 8.19 r DNA-binding transcriptional regulator Cytoplasmic JW5613 ECK3711 b3718 yieK yieK 32.86 48.35 78 92.27 1.35 1.438 1.653 1.665 35.44 37.74 43.4 43.7 26.25 6.31 pe predicted 6-phosphogluconolactonase Cytoplasmic 52512; Glucosamine 6-phosphate deaminase/isomerase JW5629 ECK3684 b4478 dgoD dgoD dgoD -!- yidU 5.85 15.49 79.68 58.64 0.768 0.764 0.735 0.451 32.6 32.46 31.21 19.15 42.47 5.77 e galactonate dehydratase Cytoplasmic JW5643 ECK3628 b3638 yicR yicR radC 9.39 16.59 25.4 40.97 2.904 2.735 2.774 2.223 73.55 69.27 70.25 56.3 25.324 9.03 cp "protein associated with replication fork, possible DNA repair protein" Cytoplasmic 47781; RuvA domain 2-like JW5676 ECK3471 b3486 rbbA rbbA yhiH -!- yhiG_1 -!- yhiG 19.83 25.77 110.83 102.91 0.06 0.046 0.011 0.048 6.03 4.63 1.1 4.81 100.672 6.1 e fused ribosome-associated ATPases Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases -!- 52540; P-loop containing nucleotide triphosphate hydrolases -!- 52540; P-loop containing nucleotide triphosphate hydrolases JW5705 ECK3320 b3333 gspL gspL yheK 18.28 33.37 46.26 72.47 0.46 0.584 0.685 0.597 20.45 25.97 30.48 26.56 44.499 6.8 pt "general secretory pathway component, cryptic" Cytoplasmic JW5727 ECK4090 b4097 phnK phnK 6.51 15 60.12 41.3 3.635 2.797 4.266 3.451 101.07 77.76 118.63 95.96 27.805 7.13 e carbon-phosphorus lyase complex subunit Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW5729 ECK4103 b4110 yjcZ yjcZ 11.24 28.61 63.33 32.83 1.005 0.955 1.196 1.235 33.05 31.39 39.3 40.59 32.872 8.31 d conserved protein Cytoplasmic 51679; Bacterial luciferase-like JW5748 ECK4211 b4215 ytfI ytfI 11.07 27.92 21.96 77.79 0.904 1.041 0.989 0.846 32.44 37.36 35.49 30.36 35.897 6.96 o predicted protein Cytoplasmic JW5752 ECK4224 b4485 ytfR ytfR ytfS 23.99 35.99 112.48 77.98 0.248 0.29 0.303 0.324 13.69 15.99 16.75 17.91 55.202 7.57 pt predicted sugar transporter subunit -! ATP-binding component of ABC superfamily Cytoplasmic JW5770 ECK4271 b4281 yjhD yjhD 12.43 28.01 25.48 119.3 4.77 3.006 5.756 5.556 42.04 26.49 50.73 48.96 8.812 8.03 h KpLE2 phage-like element; predicted protein (pseudogene) Cytoplasmic JW5775 ECK4287 b4298 yjhH yjhH 7.86 9.31 83.11 30.09 3.872 2.808 2.939 2.469 126.56 91.78 96.04 80.68 32.682 6.15 h KpLE2 phage-like element; predicted lyase/synthase Cytoplasmic 51569; Aldolase JW5776 ECK4295 b4305 sgcX sgcX yjhO 32.62 54.43 73.41 81.02 2.416 2.066 2.655 2.429 98 83.8 107.71 98.55 40.566 5.88 h KpLE2 phage-like element; predicted endoglucanase with Zn-dependent exopeptidase domain Cytoplasmic 53187; Zn-dependent exopeptidases JW5785 ECK4325 b4334 yjiL yjiL 9.87 15.26 67.99 26.85 3.349 2.989 3.038 2.767 91.2 81.38 82.71 75.32 27.227 7.2 pe "predicted ATPase, activator of (R)-hydroxyglutaryl-CoA dehydratase" Cytoplasmic 53067; Actin-like ATPase domain JW5789 ECK4335 b4345 mcrC mcrC 7.15 21.63 55.87 112.1 1.335 1.055 1.516 0.741 54.15 42.8 61.48 30.06 40.561 9.51 e "5-methylcytosine-specific restriction enzyme McrBC, subunit McrC" Cytoplasmic JW5792 ECK4347 b4357 yjjM yjjM 12.58 16.13 55.88 31.63 0.93 1.114 1.046 1.049 32.88 39.4 36.98 37.1 35.37 7.2 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46785; Winged helix JW5804 ECK1324 b1327 ycjY ycjY 14.83 24.21 76.43 88.48 1.118 1.174 1.135 1.159 38.11 40.01 38.66 39.48 34.075 5.88 pe predicted hydrolase Cytoplasmic 53474; alpha/beta-Hydrolases JW5808 ECK0142 b0143 pcnB pcnB 43.69 101.51 69.98 93.57 0.701 0.236 0.808 0.613 37.74 12.68 43.49 33.03 53.833 10.2 e poly(A) polymerase I Cytoplasmic JW5813 ECK0260 b0258 ykfC ykfC 11.8 53.49 23.48 56.24 1.313 1.615 1.817 1.83 57.4 70.61 79.45 80.02 43.723 10.82 h CP4-6 prophage; conserved protein Cytoplasmic 56672; DNA/RNA polymerases JW5818 ECK0846 b0855 potG potG 6.38 9.06 48.62 82.63 3.536 3.374 4.509 4.321 148.11 141.32 188.87 181.02 41.891 7.07 t putrescine transporter subunit -!- ATP-binding component of ABC superfamily Cytoplasmic 52540; P-loop containing nucleotide triphosphate hydrolases JW5819 ECK0859 b0868 ybjS ybjS 1.51 3.43 36.4 14.96 3.935 4.103 4.367 3.88 149.75 156.15 166.22 147.68 38.061 9.03 pe predicted NAD(P)H oxidoreductase with NAD(P)-binding Rossmann-fold domain Cytoplasmic 51735; NAD(P)-binding Rossmann-fold domains JW5838 ECK2131 b2138 yohG yohG yohH 4.59 18.37 50.77 87.07 0.808 0.682 0.816 0.679 31.72 26.75 32.01 26.62 39.236 9.7 pm predicted outer membrane protein Cytoplasmic "56954; Integral outer membrane protein TolC, efflux pump component" JW5842 ECK2542 b2545 yphC yphC 7.77 11.96 75.56 37.67 1.218 1.098 1.701 1.385 46.32 41.75 64.65 52.65 38.016 6.74 pe "predicted oxidoreductase, Zn-dependent and NAD(P)-binding" Cytoplasmic 50129; GroES-like -!- 51735; NAD(P)-binding Rossmann-fold domains JW5844 ECK2752 b2757 ygcI ygcI 9.07 13.4 70.19 32.68 1.106 1.168 1.238 1.126 27.86 29.43 31.19 28.36 25.186 7.84 o predicted protein Cytoplasmic JW5846 ECK2857 b2859 ygeO ygeO 24.4 44.53 71.41 44.49 1.685 1.422 1.752 1.444 27.62 23.3 28.71 23.66 16.39 8.39 o predicted protein Cytoplasmic JW5848 ECK2976 b2981 yghO yghO 5.39 10.82 53.43 32.21 0.588 0.625 0.702 0.731 26.22 27.88 31.32 32.64 44.631 8.03 pr predicted DNA-binding transcriptional regulator Cytoplasmic JW5849 ECK3002 b3010 yqhC yqhC 11.44 34.59 34.94 51.35 1.638 1.54 1.515 1.661 58.84 55.31 54.44 59.68 35.925 8.37 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46689; Homeodomain-like JW5867 ECK4183 b4187 aidB aidB 5.21 12.74 46.02 41.2 0.381 0.345 0.363 0.34 23.09 20.9 21.98 20.57 60.537 7.83 e isovaleryl CoA dehydrogenase Cytoplasmic "47203; Acyl-CoA dehydrogenase (flavoprotein), C-terminal domain -!- 56645; Acyl-CoA dehydrogenase (flavoprotein), N-terminal and middle domains" JW5873 ECK4366 b4375 prfC prfC tos -!- miaD 50.04 69.38 73.58 93.54 0.517 0.562 0.667 0.568 30.78 33.46 39.71 33.78 59.507 6.06 f peptide chain release factor RF-3 Cytoplasmic "50447; Translation proteins -!- 52540; P-loop containing nucleotide triphosphate hydrolases -!- 54980; Elongation factor G (EF-G), domains III and V" JW5874 ECK1645 b1649 ydhM ydhM 10.56 18.71 33.89 86.04 3.065 2.658 3.522 2.393 58.4 50.64 67.11 45.59 19.053 7.56 pr predicted DNA-binding transcriptional regulator Cytoplasmic 46689; Homeodomain-like JW5878 ECK2532 b2535 csiE csiE csi-16 9.17 11.39 36.6 42.13 0.754 0.82 0.773 0.781 36.97 40.19 37.89 38.27 48.998 7.87 cp stationary phase inducible protein Cytoplasmic "63520; PTS-regulatory domain, PRD"