TP構造ギャラリー
3W0J
PDB ID | 3W0J | |
Protein | VDR | |
Comment | TTYN8 complex | |
PubMed ID | 23462137 | |
Authors | Asano L, Ito I, Kuwabara N, Waku T, Yanagisawa J, Miyachi H, Shimizu T. | |
Title | Structural basis for vitamin D receptor agonism by novel nonsecosteroidal ligands. | |
Method | X-ray diffraction | |
Resolution | 1.80 |
分子情報[1]
Protein | SRC1 |
Organism | Homo sapiens |
Uniprot | Q15648 |
Sequence | 625-637 |
Ligand | |
Vector | |
Expression host | Synthetic construct |
Cell culture | |
Protein purification |
分子情報[2]
Protein | VDR |
Organism | Rattus norvegicus |
Uniprot | P13053 |
Sequence | ligand binding domain(116-423) lacking the flexible insertion region(165-211) |
Ligand | TTYN8 |
Vector | |
Expression host | Escherichia coli (BL21(DE3)) |
Cell culture | |
Protein purification | Ni-NTA, Superdex 200 |
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